ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MAPK3
Previous Symbol	PRKM3
Symbol Alias	ERK1, p44mapk, p44erk1
Approved Name	mitogen-activated protein kinase 3
Location	16p11.2
Position	chr16:30125426-30134827, -1
External Links	HGNC: 6877 Entrez Gene: 5595 Ensembl: ENSG00000102882 UCSC: uc002dws.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 4)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_16	chr16:29563594-30367556 (NCBI Build 36.1 (hg18))	803963	16p11.2	Loss
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Williams[2010]_39	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813247	16p11.2	Gain
CNV_Jarick[2012]_35	chr16:29554843-30085308 (NCBI36 / hg18)	530466	16p11.2	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 73)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051493	regulation of cytoskeleton organization	biological process	TAS[19565474]	5

GO terms by database search (count: 72)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0031143	pseudopodium	cellular component	IEA	4
GO:0019233	sensory perception of pain	biological process	IEA	18
GO:0008543	fibroblast growth factor receptor signaling pathway	biological process	TAS	33
GO:0007265	Ras protein signal transduction	biological process	TAS	15
GO:0006915	apoptotic process	biological process	IEA	127
GO:0043330	response to exogenous dsRNA	biological process	IEA	2
GO:0001934	positive regulation of protein phosphorylation	biological process	IMP[19664780]	24
GO:0000165	MAPK cascade	biological process	NAS; TAS	10
GO:0034138	toll-like receptor 3 signaling pathway	biological process	TAS	11
GO:0002756	MyD88-independent toll-like receptor signaling pathway	biological process	TAS	9
GO:2000641	regulation of early endosome to late endosome transport	biological process	TAS[19565474]	2
GO:0031663	lipopolysaccharide-mediated signaling pathway	biological process	IEA	5
GO:0034142	toll-like receptor 4 signaling pathway	biological process	TAS	11
GO:0005925	focal adhesion	cellular component	TAS[19565474]	26
GO:0019902	phosphatase binding	molecular function	IPI[19494114]	9
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0005730	nucleolus	cellular component	IDA	271
GO:0000187	activation of MAPK activity	biological process	TAS	22
GO:0005829	cytosol	cellular component	TAS	485
GO:0034130	toll-like receptor 1 signaling pathway	biological process	TAS	10
GO:0005856	cytoskeleton	cellular component	TAS[19565474]	56
GO:0000186	activation of MAPKK activity	biological process	TAS	9
GO:0015630	microtubule cytoskeleton	cellular component	IDA	35
GO:0004707	MAP kinase activity	molecular function	IDA[8388392]; NAS[7687743]; TAS	3
GO:0005739	mitochondrion	cellular component	TAS[19565474]	221
GO:0030168	platelet activation	biological process	TAS	38
GO:0007264	small GTPase mediated signal transduction	biological process	TAS	65
GO:0033129	positive regulation of histone phosphorylation	biological process	IMP	2
GO:0005769	early endosome	cellular component	TAS[19565474]	27
GO:0070849	response to epidermal growth factor stimulus	biological process	IDA[18794356]	2
GO:0006468	protein phosphorylation	biological process	IDA[7687743]	58
GO:0070374	positive regulation of ERK1 and ERK2 cascade	biological process	IMP[19664780]	23
GO:0006361	transcription initiation from RNA polymerase I promoter	biological process	TAS	6
GO:2000657	negative regulation of apolipoprotein binding	biological process	IEA	1
GO:0007411	axon guidance	biological process	TAS	71
GO:0008286	insulin receptor signaling pathway	biological process	TAS	37
GO:0007596	blood coagulation	biological process	TAS	85
GO:0070498	interleukin-1-mediated signaling pathway	biological process	IMP	2
GO:0051216	cartilage development	biological process	IEA	12
GO:0008063	Toll signaling pathway	biological process	TAS	11
GO:0001784	phosphotyrosine binding	molecular function	IEA	4
GO:0005515	protein binding	molecular function	IPI[19776015]	1015
GO:0071260	cellular response to mechanical stimulus	biological process	IEP[19593445]	14
GO:0005770	late endosome	cellular component	TAS[19565474]	15
GO:0005794	Golgi apparatus	cellular component	TAS[19565474]	174
GO:0009887	organ morphogenesis	biological process	IEA	19
GO:0048011	nerve growth factor receptor signaling pathway	biological process	TAS	51
GO:0072584	caveolin-mediated endocytosis	biological process	TAS[19565474]	2
GO:0019221	cytokine-mediated signaling pathway	biological process	TAS	33
GO:0005524	ATP binding	molecular function	NAS	265
GO:0002224	toll-like receptor signaling pathway	biological process	TAS	10
GO:0045087	innate immune response	biological process	TAS	57
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological process	IMP	141
GO:0006974	response to DNA damage stimulus	biological process	IEA	41
GO:0030509	BMP signaling pathway	biological process	IMP[19664780]	4
GO:0090170	regulation of Golgi inheritance	biological process	TAS[19565474]	2
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	biological process	TAS	6
GO:0051403	stress-activated MAPK cascade	biological process	TAS	10
GO:0005901	caveola	cellular component	TAS[19565474]	13
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	biological process	TAS	17
GO:0010467	gene expression	biological process	TAS	154
GO:0006360	transcription from RNA polymerase I promoter	biological process	TAS	6
GO:0007049	cell cycle	biological process	IEA	36
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	biological process	TAS	10
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	biological process	TAS	10
GO:0019048	virus-host interaction	biological process	IEA	61
GO:0034134	toll-like receptor 2 signaling pathway	biological process	TAS	10
GO:0038083	peptidyl-tyrosine autophosphorylation	biological process	IDA[8388392]	1
GO:0032872	regulation of stress-activated MAPK cascade	biological process	TAS[19565474]	4
GO:0005634	nucleus	cellular component	IDA; TAS[19565474]	877
GO:0035066	positive regulation of histone acetylation	biological process	IMP	3
GO:0007173	epidermal growth factor receptor signaling pathway	biological process	TAS	32

Gene related KEGG pathways (count: 31)

ID	Name	No. of Genes in ADHDgene
hsa04370	VEGF signaling pathway	18
hsa04360	Axon guidance	26
hsa04510	Focal adhesion	40
hsa04520	Adherens junction	15
hsa04540	Gap junction	30
hsa04150	mTOR signaling pathway	15
hsa04350	TGF-beta signaling pathway	11
hsa04664	Fc epsilon RI signaling pathway	19
hsa04720	Long-term potentiation	16
hsa04730	Long-term depression	27
hsa04620	Toll-like receptor signaling pathway	14
hsa04650	Natural killer cell mediated cytotoxicity	15
hsa04916	Melanogenesis	18
hsa04912	GnRH signaling pathway	30
hsa04910	Insulin signaling pathway	29
hsa04810	Regulation of actin cytoskeleton	49
hsa04930	Type II diabetes mellitus	13
hsa05218	Melanoma	13
hsa04010	MAPK signaling pathway	68
hsa05219	Bladder cancer	7
hsa05216	Thyroid cancer	3
hsa05223	Non-small cell lung cancer	10
hsa05220	Chronic myeloid leukemia	12
hsa05221	Acute myeloid leukemia	10
hsa05210	Colorectal cancer	13
hsa05211	Renal cell carcinoma	15
hsa05214	Glioma	8
hsa05215	Prostate cancer	16
hsa05212	Pancreatic cancer	13
hsa04012	ErbB signaling pathway	20
hsa05213	Endometrial cancer	14

Genes shared at least 5 GO terms with MAPK3 (count: 221)

Gene Symbol	Pathway Count	Pathway List
MAPK1	57	pseudopodium; sensory perception of pain; fibroblast growth factor receptor signaling pathway; Ras protein signal transduction; apoptotic process; response to exogenous dsRNA; MAPK cascade; toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; regulation of early endosome to late endosome transport; lipopolysaccharide-mediated signaling pathway; toll-like receptor 4 signaling pathway; focal adhesion; phosphatase binding; nucleoplasm; nucleolus; activation of MAPK activity; cytosol; toll-like receptor 1 signaling pathway; cytoskeleton; activation of MAPKK activity; microtubule cytoskeleton; MAP kinase activity; mitochondrion; platelet activation; small GTPase mediated signal transduction; early endosome; response to epidermal growth factor stimulus; axon guidance; insulin receptor signaling pathway; blood coagulation; regulation of cytoskeleton organization; Toll signaling pathway; phosphotyrosine binding; protein binding; late endosome; Golgi apparatus; organ morphogenesis; nerve growth factor receptor signaling pathway; caveolin-mediated endocytosis; ATP binding; toll-like receptor signaling pathway; innate immune response; response to DNA damage stimulus; regulation of Golgi inheritance; JAK-STAT cascade involved in growth hormone signaling pathway; stress-activated MAPK cascade; caveola; regulation of sequence-specific DNA binding transcription factor activity; cell cycle; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; virus-host interaction; toll-like receptor 2 signaling pathway; regulation of stress-activated MAPK cascade; nucleus; epidermal growth factor receptor signaling pathway;
UBC	22	fibroblast growth factor receptor signaling pathway; apoptotic process; toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; activation of MAPK activity; cytosol; toll-like receptor 1 signaling pathway; Toll signaling pathway; protein binding; nerve growth factor receptor signaling pathway; cytokine-mediated signaling pathway; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; stress-activated MAPK cascade; gene expression; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway; epidermal growth factor receptor signaling pathway;
UBB	22	fibroblast growth factor receptor signaling pathway; apoptotic process; toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; activation of MAPK activity; cytosol; toll-like receptor 1 signaling pathway; Toll signaling pathway; protein binding; nerve growth factor receptor signaling pathway; cytokine-mediated signaling pathway; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; stress-activated MAPK cascade; gene expression; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway; epidermal growth factor receptor signaling pathway;
MAPK7	21	apoptotic process; toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; cytosol; toll-like receptor 1 signaling pathway; MAP kinase activity; Toll signaling pathway; protein binding; nerve growth factor receptor signaling pathway; ATP binding; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; stress-activated MAPK cascade; cell cycle; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway; nucleus;
RELA	19	toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; cytosol; toll-like receptor 1 signaling pathway; Toll signaling pathway; protein binding; organ morphogenesis; nerve growth factor receptor signaling pathway; cytokine-mediated signaling pathway; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; virus-host interaction; toll-like receptor 2 signaling pathway; nucleus;
MAPK9	18	positive regulation of protein phosphorylation; toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; cytosol; toll-like receptor 1 signaling pathway; mitochondrion; Toll signaling pathway; protein binding; ATP binding; toll-like receptor signaling pathway; innate immune response; stress-activated MAPK cascade; regulation of sequence-specific DNA binding transcription factor activity; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway;
MAP2K3	16	toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; activation of MAPK activity; cytosol; toll-like receptor 1 signaling pathway; Toll signaling pathway; protein binding; ATP binding; toll-like receptor signaling pathway; innate immune response; stress-activated MAPK cascade; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway;
TLR4	15	toll-like receptor 3 signaling pathway; lipopolysaccharide-mediated signaling pathway; toll-like receptor 4 signaling pathway; activation of MAPK activity; toll-like receptor 1 signaling pathway; positive regulation of ERK1 and ERK2 cascade; Toll signaling pathway; protein binding; cellular response to mechanical stimulus; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway;
IRF7	14	toll-like receptor 3 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; nucleoplasm; cytosol; protein phosphorylation; Toll signaling pathway; protein binding; cytokine-mediated signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; TRIF-dependent toll-like receptor signaling pathway; nucleus;
GSK3B	12	fibroblast growth factor receptor signaling pathway; nucleolus; cytosol; protein phosphorylation; axon guidance; protein binding; organ morphogenesis; nerve growth factor receptor signaling pathway; ATP binding; positive regulation of transcription from RNA polymerase II promoter; nucleus; epidermal growth factor receptor signaling pathway;
PDPK1	12	fibroblast growth factor receptor signaling pathway; focal adhesion; nucleoplasm; cytosol; platelet activation; protein phosphorylation; insulin receptor signaling pathway; blood coagulation; protein binding; nerve growth factor receptor signaling pathway; ATP binding; epidermal growth factor receptor signaling pathway;
PIK3R1	11	fibroblast growth factor receptor signaling pathway; cytosol; platelet activation; protein phosphorylation; insulin receptor signaling pathway; blood coagulation; protein binding; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; virus-host interaction; epidermal growth factor receptor signaling pathway;
TSC2	10	fibroblast growth factor receptor signaling pathway; phosphatase binding; cytosol; insulin receptor signaling pathway; protein binding; Golgi apparatus; nerve growth factor receptor signaling pathway; caveola; nucleus; epidermal growth factor receptor signaling pathway;
RPS6KA4	10	nucleolus; positive regulation of histone phosphorylation; protein phosphorylation; axon guidance; interleukin-1-mediated signaling pathway; protein binding; ATP binding; positive regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of histone acetylation;
ARRB1	9	pseudopodium; cytosol; platelet activation; positive regulation of ERK1 and ERK2 cascade; blood coagulation; protein binding; positive regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of histone acetylation;
BAD	9	fibroblast growth factor receptor signaling pathway; apoptotic process; cytosol; mitochondrion; protein binding; cellular response to mechanical stimulus; nerve growth factor receptor signaling pathway; cytokine-mediated signaling pathway; epidermal growth factor receptor signaling pathway;
PAK1	9	apoptotic process; MAPK cascade; focal adhesion; cytosol; protein phosphorylation; axon guidance; protein binding; Golgi apparatus; ATP binding;
AATF	9	apoptotic process; focal adhesion; nucleolus; protein binding; Golgi apparatus; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; nucleus;
MEN1	9	MAPK cascade; nucleoplasm; nucleolus; cytosol; protein binding; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; gene expression; nucleus;
TIRAP	9	toll-like receptor 4 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of ERK1 and ERK2 cascade; Toll signaling pathway; protein binding; toll-like receptor signaling pathway; innate immune response; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 2 signaling pathway;
SYK	9	cytosol; platelet activation; protein phosphorylation; blood coagulation; protein binding; organ morphogenesis; ATP binding; innate immune response; virus-host interaction;
SQSTM1	8	apoptotic process; positive regulation of protein phosphorylation; nucleoplasm; cytosol; protein binding; late endosome; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter;
PSMC3	8	apoptotic process; nucleoplasm; cytosol; protein binding; ATP binding; gene expression; virus-host interaction; nucleus;
TAOK2	8	apoptotic process; nucleolus; cytoskeleton; activation of MAPKK activity; ATP binding; response to DNA damage stimulus; stress-activated MAPK cascade; nucleus;
PRKD1	8	apoptotic process; cytosol; protein binding; Golgi apparatus; ATP binding; innate immune response; positive regulation of transcription from RNA polymerase II promoter; nucleus;
BCAR1	8	focal adhesion; cytosol; platelet activation; insulin receptor signaling pathway; blood coagulation; protein binding; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
STK11	8	cytosol; mitochondrion; protein phosphorylation; insulin receptor signaling pathway; protein binding; ATP binding; response to DNA damage stimulus; nucleus;
CEP57	7	fibroblast growth factor receptor signaling pathway; nucleolus; cytosol; microtubule cytoskeleton; protein binding; Golgi apparatus; nucleus;
FGF4	7	fibroblast growth factor receptor signaling pathway; positive regulation of protein phosphorylation; cytosol; positive regulation of ERK1 and ERK2 cascade; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; nucleus;
WWOX	7	apoptotic process; cytosol; mitochondrion; protein binding; Golgi apparatus; positive regulation of transcription from RNA polymerase II promoter; nucleus;
TRIO	7	apoptotic process; cytosol; small GTPase mediated signal transduction; axon guidance; protein binding; nerve growth factor receptor signaling pathway; ATP binding;
SGK1	7	apoptotic process; mitochondrion; protein phosphorylation; ATP binding; response to DNA damage stimulus; regulation of sequence-specific DNA binding transcription factor activity; nucleus;
FADD	7	apoptotic process; cytosol; protein binding; cellular response to mechanical stimulus; innate immune response; positive regulation of transcription from RNA polymerase II promoter; virus-host interaction;
BNIP3	7	apoptotic process; nucleoplasm; mitochondrion; protein binding; cellular response to mechanical stimulus; virus-host interaction; nucleus;
ERBB2	7	positive regulation of protein phosphorylation; protein phosphorylation; axon guidance; protein binding; ATP binding; nucleus; epidermal growth factor receptor signaling pathway;
FES	7	focal adhesion; cytosol; microtubule cytoskeleton; protein phosphorylation; axon guidance; Golgi apparatus; ATP binding;
YAP1	7	nucleoplasm; cytosol; protein binding; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; gene expression; nucleus;
SNW1	7	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; virus-host interaction; nucleus;
MAML1	7	nucleoplasm; nucleolus; protein phosphorylation; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
DDX23	7	nucleoplasm; nucleolus; mitochondrion; protein binding; ATP binding; gene expression; nucleus;
SMARCB1	7	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; cell cycle; virus-host interaction; nucleus;
CHEK1	7	nucleoplasm; cytosol; protein binding; cellular response to mechanical stimulus; ATP binding; response to DNA damage stimulus; nucleus;
HSPA8	7	nucleolus; cytosol; protein binding; ATP binding; gene expression; virus-host interaction; nucleus;
PRKAA1	7	activation of MAPK activity; cytosol; protein phosphorylation; insulin receptor signaling pathway; protein binding; ATP binding; nucleus;
MAP2K5	7	activation of MAPK activity; cytosol; protein binding; nerve growth factor receptor signaling pathway; ATP binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
CRYAB	7	cytosol; microtubule cytoskeleton; mitochondrion; protein binding; Golgi apparatus; stress-activated MAPK cascade; nucleus;
PIK3C3	7	cytosol; insulin receptor signaling pathway; protein binding; late endosome; ATP binding; innate immune response; cell cycle;
KARS	7	cytosol; microtubule cytoskeleton; mitochondrion; ATP binding; gene expression; virus-host interaction; nucleus;
NGF	6	sensory perception of pain; Ras protein signal transduction; apoptotic process; activation of MAPKK activity; small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway;
RAB14	6	fibroblast growth factor receptor signaling pathway; cytosol; small GTPase mediated signal transduction; early endosome; protein binding; late endosome;
ADRBK1	6	fibroblast growth factor receptor signaling pathway; cytosol; protein binding; nerve growth factor receptor signaling pathway; ATP binding; epidermal growth factor receptor signaling pathway;
CTGF	6	fibroblast growth factor receptor signaling pathway; positive regulation of protein phosphorylation; cytosol; positive regulation of ERK1 and ERK2 cascade; Golgi apparatus; gene expression;
MLST8	6	fibroblast growth factor receptor signaling pathway; cytosol; insulin receptor signaling pathway; protein binding; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
CBL	6	fibroblast growth factor receptor signaling pathway; cytosol; phosphotyrosine binding; protein binding; nucleus; epidermal growth factor receptor signaling pathway;
ITPR1	6	fibroblast growth factor receptor signaling pathway; platelet activation; blood coagulation; protein binding; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
FGF10	6	fibroblast growth factor receptor signaling pathway; activation of MAPK activity; positive regulation of ERK1 and ERK2 cascade; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; nucleus;
SHC3	6	Ras protein signal transduction; cytosol; insulin receptor signaling pathway; protein binding; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
EGLN3	6	apoptotic process; nucleoplasm; cytosol; protein binding; response to DNA damage stimulus; nucleus;
ARHGEF2	6	apoptotic process; cytosol; small GTPase mediated signal transduction; protein binding; Golgi apparatus; nerve growth factor receptor signaling pathway;
FGD3	6	apoptotic process; cytosol; cytoskeleton; small GTPase mediated signal transduction; Golgi apparatus; nerve growth factor receptor signaling pathway;
PMAIP1	6	apoptotic process; cytosol; mitochondrion; protein binding; response to DNA damage stimulus; nucleus;
ARHGEF12	6	apoptotic process; cytosol; small GTPase mediated signal transduction; axon guidance; protein binding; nerve growth factor receptor signaling pathway;
GATA6	6	apoptotic process; nucleoplasm; blood coagulation; protein binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
DAXX	6	apoptotic process; nucleolus; cytosol; protein binding; virus-host interaction; nucleus;
PSMB7	6	apoptotic process; nucleoplasm; cytosol; protein binding; gene expression; virus-host interaction;
ADAM17	6	positive regulation of protein phosphorylation; focal adhesion; protein binding; nerve growth factor receptor signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; epidermal growth factor receptor signaling pathway;
CCND1	6	positive regulation of protein phosphorylation; nucleoplasm; cytosol; protein binding; response to DNA damage stimulus; nucleus;
MAP3K5	6	MAPK cascade; activation of MAPKK activity; protein binding; ATP binding; innate immune response; virus-host interaction;
NCOA6	6	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; nucleus;
RBPJ	6	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
CREBBP	6	nucleoplasm; protein binding; innate immune response; gene expression; virus-host interaction; nucleus;
SNRNP200	6	nucleoplasm; nucleolus; protein binding; ATP binding; gene expression; nucleus;
ESRRA	6	nucleoplasm; cartilage development; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
RAN	6	nucleoplasm; cytosol; small GTPase mediated signal transduction; protein binding; gene expression; virus-host interaction;
XPO1	6	nucleoplasm; nucleolus; cytosol; protein binding; gene expression; virus-host interaction;
SART1	6	nucleoplasm; nucleolus; cytosol; protein binding; Golgi apparatus; nucleus;
NEDD4L	6	nucleoplasm; cytosol; protein binding; gene expression; virus-host interaction; nucleus;
DGCR8	6	nucleoplasm; nucleolus; microtubule cytoskeleton; protein binding; gene expression; nucleus;
KIF23	6	nucleoplasm; cytosol; blood coagulation; protein binding; ATP binding; nucleus;
DHX9	6	nucleoplasm; nucleolus; protein binding; ATP binding; gene expression; nucleus;
SMC1A	6	nucleoplasm; nucleolus; protein binding; ATP binding; gene expression; nucleus;
MED1	6	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
PLK1	6	nucleoplasm; cytosol; protein phosphorylation; protein binding; ATP binding; nucleus;
STXBP3	6	nucleolus; cytosol; platelet activation; blood coagulation; protein binding; nucleus;
ALKBH8	6	nucleolus; cytosol; microtubule cytoskeleton; protein binding; response to DNA damage stimulus; nucleus;
KAT5	6	nucleolus; cytosol; protein binding; positive regulation of transcription from RNA polymerase II promoter; virus-host interaction; nucleus;
IARS	6	nucleolus; cytosol; protein binding; ATP binding; gene expression; nucleus;
DCPS	6	nucleolus; cytosol; mitochondrion; protein binding; gene expression; nucleus;
TRIM5	6	nucleolus; protein binding; Golgi apparatus; innate immune response; virus-host interaction; nucleus;
HK1	6	nucleolus; cytosol; mitochondrion; protein binding; ATP binding; nucleus;
PIK3CG	6	cytosol; platelet activation; blood coagulation; protein binding; ATP binding; innate immune response;
HABP4	6	cytosol; platelet activation; blood coagulation; protein binding; cellular response to mechanical stimulus; nucleus;
PRKG1	6	cytosol; protein phosphorylation; blood coagulation; protein binding; Golgi apparatus; ATP binding;
ROCK2	6	cytosol; protein phosphorylation; axon guidance; protein binding; ATP binding; nucleus;
ARRB2	6	cytosol; platelet activation; positive regulation of ERK1 and ERK2 cascade; blood coagulation; protein binding; nucleus;
PDE2A	6	cytosol; blood coagulation; protein binding; cellular response to mechanical stimulus; Golgi apparatus; nucleus;
PYCARD	6	cytosol; mitochondrion; positive regulation of ERK1 and ERK2 cascade; protein binding; innate immune response; nucleus;
RNASEL	6	cytosol; mitochondrion; protein phosphorylation; cytokine-mediated signaling pathway; ATP binding; positive regulation of transcription from RNA polymerase II promoter;
KIF2C	6	cytosol; microtubule cytoskeleton; blood coagulation; protein binding; ATP binding; nucleus;
CFL1	6	platelet activation; protein phosphorylation; axon guidance; blood coagulation; protein binding; nucleus;
SIK2	6	protein phosphorylation; insulin receptor signaling pathway; protein binding; Golgi apparatus; ATP binding; nucleus;
ADCY4	5	fibroblast growth factor receptor signaling pathway; protein binding; nerve growth factor receptor signaling pathway; ATP binding; epidermal growth factor receptor signaling pathway;
MAPKAP1	5	fibroblast growth factor receptor signaling pathway; cytosol; nerve growth factor receptor signaling pathway; nucleus; epidermal growth factor receptor signaling pathway;
ITPR2	5	fibroblast growth factor receptor signaling pathway; platelet activation; blood coagulation; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
RICTOR	5	fibroblast growth factor receptor signaling pathway; cytosol; protein binding; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
PRKAR2B	5	fibroblast growth factor receptor signaling pathway; cytosol; blood coagulation; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway;
RPS6KB2	5	fibroblast growth factor receptor signaling pathway; nucleoplasm; nerve growth factor receptor signaling pathway; ATP binding; epidermal growth factor receptor signaling pathway;
PLCE1	5	Ras protein signal transduction; activation of MAPK activity; cytosol; protein binding; epidermal growth factor receptor signaling pathway;
APC	5	apoptotic process; cytosol; protein binding; response to DNA damage stimulus; nucleus;
APBB1	5	apoptotic process; axon guidance; protein binding; response to DNA damage stimulus; nucleus;
PSMD7	5	apoptotic process; nucleoplasm; cytosol; protein binding; gene expression;
ARF6	5	apoptotic process; small GTPase mediated signal transduction; early endosome; protein binding; Golgi apparatus;
AXIN1	5	apoptotic process; positive regulation of protein phosphorylation; cytosol; protein binding; nucleus;
KRT18	5	apoptotic process; nucleolus; protein binding; cell cycle; virus-host interaction;
ARHGEF4	5	apoptotic process; cytosol; small GTPase mediated signal transduction; protein binding; nerve growth factor receptor signaling pathway;
PERP	5	apoptotic process; nucleolus; mitochondrion; Golgi apparatus; nucleus;
TGFBR1	5	apoptotic process; activation of MAPKK activity; protein phosphorylation; protein binding; ATP binding;
NET1	5	apoptotic process; cytosol; small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; nucleus;
POLR2G	5	apoptotic process; nucleoplasm; protein phosphorylation; gene expression; nucleus;
PDCD4	5	apoptotic process; nucleolus; cytosol; protein binding; nucleus;
CASP1	5	apoptotic process; cytosol; protein binding; cellular response to mechanical stimulus; innate immune response;
PSMD5	5	apoptotic process; nucleoplasm; cytosol; protein binding; gene expression;
MCF2L	5	apoptotic process; cytosol; small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter;
NEK6	5	apoptotic process; protein phosphorylation; protein binding; ATP binding; nucleus;
VEGFA	5	positive regulation of protein phosphorylation; platelet activation; blood coagulation; protein binding; positive regulation of transcription from RNA polymerase II promoter;
MAVS	5	positive regulation of protein phosphorylation; protein binding; innate immune response; positive regulation of transcription from RNA polymerase II promoter; virus-host interaction;
FLT4	5	positive regulation of protein phosphorylation; positive regulation of ERK1 and ERK2 cascade; protein binding; ATP binding; nucleus;
GAK	5	focal adhesion; protein binding; Golgi apparatus; ATP binding; cell cycle;
SORBS3	5	focal adhesion; cytosol; cytoskeleton; protein binding; nucleus;
KIF22	5	focal adhesion; cytosol; blood coagulation; ATP binding; nucleus;
ILK	5	focal adhesion; cytosol; protein phosphorylation; protein binding; ATP binding;
MAML2	5	nucleoplasm; Golgi apparatus; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
RAD9A	5	nucleoplasm; nucleolus; protein binding; response to DNA damage stimulus; nucleus;
NCOR2	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
U2AF1	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
NXF1	5	nucleoplasm; cytosol; protein binding; gene expression; virus-host interaction;
RBM4	5	nucleoplasm; nucleolus; protein binding; stress-activated MAPK cascade; nucleus;
HNRNPH1	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
RAD1	5	nucleoplasm; nucleolus; protein binding; response to DNA damage stimulus; nucleus;
POLD3	5	nucleoplasm; nucleolus; mitochondrion; protein binding; nucleus;
RRN3	5	nucleoplasm; nucleolus; transcription initiation from RNA polymerase I promoter; gene expression; transcription from RNA polymerase I promoter;
TP53BP1	5	nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; nucleus;
NR5A1	5	nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
POLR3E	5	nucleoplasm; nucleolus; innate immune response; gene expression; nucleus;
MRE11A	5	nucleoplasm; nucleolus; protein binding; response to DNA damage stimulus; nucleus;
RNPS1	5	nucleoplasm; cytosol; protein binding; gene expression; nucleus;
GTF2H3	5	nucleoplasm; protein phosphorylation; transcription initiation from RNA polymerase I promoter; gene expression; transcription from RNA polymerase I promoter;
TCEB1	5	nucleoplasm; cytosol; protein binding; gene expression; virus-host interaction;
SSRP1	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
KDM1A	5	nucleoplasm; blood coagulation; protein binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
SF3A1	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
FEN1	5	nucleoplasm; nucleolus; mitochondrion; protein binding; nucleus;
TXN	5	nucleoplasm; cytosol; mitochondrion; protein binding; innate immune response;
CAMK2D	5	nucleoplasm; cytosol; protein phosphorylation; cytokine-mediated signaling pathway; ATP binding;
SF3A3	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
RPS2	5	nucleoplasm; nucleolus; cytosol; protein binding; gene expression;
USP28	5	nucleoplasm; nucleolus; protein binding; response to DNA damage stimulus; nucleus;
SF3B2	5	nucleoplasm; nucleolus; gene expression; virus-host interaction; nucleus;
SNRPD1	5	nucleoplasm; cytosol; protein binding; gene expression; nucleus;
TAF1B	5	nucleoplasm; transcription initiation from RNA polymerase I promoter; gene expression; transcription from RNA polymerase I promoter; nucleus;
NUMA1	5	nucleoplasm; nucleolus; cytosol; protein binding; nucleus;
PRPF4	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
TAF13	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
TLE1	5	nucleoplasm; cytosol; protein binding; organ morphogenesis; nucleus;
STRN3	5	nucleoplasm; protein binding; Golgi apparatus; positive regulation of transcription from RNA polymerase II promoter; nucleus;
PGR	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
NCBP1	5	nucleoplasm; cytosol; protein binding; gene expression; nucleus;
HMGA1	5	nucleoplasm; cytosol; protein binding; virus-host interaction; nucleus;
ATXN1	5	nucleoplasm; nucleolus; protein binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
XRCC5	5	nucleoplasm; nucleolus; protein binding; ATP binding; nucleus;
HNRNPA1	5	nucleoplasm; nucleolus; gene expression; virus-host interaction; nucleus;
CIITA	5	nucleoplasm; protein binding; cytokine-mediated signaling pathway; ATP binding; positive regulation of transcription from RNA polymerase II promoter;
MED15	5	nucleoplasm; protein binding; Golgi apparatus; gene expression; nucleus;
POLR1A	5	nucleoplasm; transcription initiation from RNA polymerase I promoter; protein binding; gene expression; transcription from RNA polymerase I promoter;
HNRNPA2B1	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
IRF9	5	nucleoplasm; cytosol; protein binding; cytokine-mediated signaling pathway; nucleus;
FUS	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
MED4	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
GEMIN2	5	nucleoplasm; cytosol; protein binding; gene expression; nucleus;
EFTUD2	5	nucleoplasm; nucleolus; protein binding; gene expression; nucleus;
PRPF6	5	nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
NR4A2	5	nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus;
PARN	5	nucleolus; cytosol; protein binding; gene expression; nucleus;
MALT1	5	nucleolus; cytosol; protein binding; innate immune response; nucleus;
COG5	5	nucleolus; cytosol; protein binding; Golgi apparatus; nucleus;
FOXD4	5	nucleolus; cartilage development; positive regulation of transcription from RNA polymerase II promoter; regulation of sequence-specific DNA binding transcription factor activity; nucleus;
NF2	5	nucleolus; cytoskeleton; early endosome; protein binding; nucleus;
SRP19	5	nucleolus; cytosol; mitochondrion; gene expression; nucleus;
HKDC1	5	nucleolus; cytosol; mitochondrion; ATP binding; nucleus;
CHD1L	5	nucleolus; protein binding; ATP binding; response to DNA damage stimulus; nucleus;
PPP1CA	5	nucleolus; cytosol; protein binding; cell cycle; nucleus;
THRAP3	5	nucleolus; protein binding; ATP binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
BAIAP2	5	nucleolus; cytosol; insulin receptor signaling pathway; protein binding; nucleus;
GHR	5	activation of MAPK activity; mitochondrion; protein binding; JAK-STAT cascade involved in growth hormone signaling pathway; nucleus;
USP7	5	cytosol; protein binding; regulation of sequence-specific DNA binding transcription factor activity; virus-host interaction; nucleus;
LATS2	5	cytosol; protein phosphorylation; protein binding; ATP binding; nucleus;
CSNK1E	5	cytosol; protein phosphorylation; protein binding; ATP binding; nucleus;
HERC5	5	cytosol; protein binding; cytokine-mediated signaling pathway; innate immune response; nucleus;
GSTP1	5	cytosol; mitochondrion; protein binding; regulation of stress-activated MAPK cascade; nucleus;
TH	5	cytosol; mitochondrion; protein binding; organ morphogenesis; nucleus;
NCK2	5	cytosol; axon guidance; protein binding; positive regulation of transcription from RNA polymerase II promoter; epidermal growth factor receptor signaling pathway;
RQCD1	5	cytosol; protein binding; cytokine-mediated signaling pathway; gene expression; nucleus;
DNAJA3	5	cytosol; small GTPase mediated signal transduction; protein binding; ATP binding; nucleus;
RPS3	5	cytosol; protein binding; response to DNA damage stimulus; gene expression; nucleus;
SMG1	5	cytosol; protein binding; ATP binding; gene expression; nucleus;
CLNS1A	5	cytosol; cytoskeleton; protein binding; gene expression; nucleus;
SNCA	5	cytosol; mitochondrion; protein binding; Golgi apparatus; nucleus;
RIPK3	5	cytosol; mitochondrion; protein binding; ATP binding; innate immune response;
UBE3A	5	cytosol; protein binding; positive regulation of transcription from RNA polymerase II promoter; virus-host interaction; nucleus;
SOCS1	5	cytosol; protein binding; cytokine-mediated signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; nucleus;
POTEKP	5	cytosol; cytoskeleton; platelet activation; blood coagulation; ATP binding;
PARK2	5	cytosol; mitochondrion; protein binding; Golgi apparatus; nucleus;
NCK1	5	cytosol; axon guidance; protein binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
GLYCTK	5	mitochondrion; protein phosphorylation; protein binding; Golgi apparatus; ATP binding;
DARS2	5	mitochondrion; protein binding; ATP binding; gene expression; nucleus;
CYBA	5	mitochondrion; protein binding; cellular response to mechanical stimulus; Golgi apparatus; innate immune response;
HSPA5	5	platelet activation; blood coagulation; protein binding; ATP binding; nucleus;
RAB27A	5	small GTPase mediated signal transduction; blood coagulation; protein binding; late endosome; Golgi apparatus;
STK36	5	protein phosphorylation; protein binding; ATP binding; regulation of sequence-specific DNA binding transcription factor activity; nucleus;
MARK2	5	protein phosphorylation; regulation of cytoskeleton organization; protein binding; ATP binding; nucleus;
ITGA2	5	axon guidance; blood coagulation; protein binding; organ morphogenesis; virus-host interaction;

Genes shared at least 2 KEGG pathways with MAPK3 (count: 99)

Gene Symbol	Pathway Count	Pathway List
MAPK1	31	VEGF signaling pathway; Axon guidance; Focal adhesion; Adherens junction; Gap junction; mTOR signaling pathway; TGF-beta signaling pathway; Fc epsilon RI signaling pathway; Long-term potentiation; Long-term depression; Toll-like receptor signaling pathway; Natural killer cell mediated cytotoxicity; Melanogenesis; GnRH signaling pathway; Insulin signaling pathway; Regulation of actin cytoskeleton; Type II diabetes mellitus; Melanoma; MAPK signaling pathway; Bladder cancer; Thyroid cancer; Non-small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Colorectal cancer; Renal cell carcinoma; Glioma; Prostate cancer; Pancreatic cancer; ErbB signaling pathway; Endometrial cancer;
PIK3CG	20	VEGF signaling pathway; Focal adhesion; mTOR signaling pathway; Fc epsilon RI signaling pathway; Toll-like receptor signaling pathway; Natural killer cell mediated cytotoxicity; Insulin signaling pathway; Regulation of actin cytoskeleton; Type II diabetes mellitus; Melanoma; Non-small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Colorectal cancer; Renal cell carcinoma; Glioma; Prostate cancer; Pancreatic cancer; ErbB signaling pathway; Endometrial cancer;
PIK3R1	20	VEGF signaling pathway; Focal adhesion; mTOR signaling pathway; Fc epsilon RI signaling pathway; Toll-like receptor signaling pathway; Natural killer cell mediated cytotoxicity; Insulin signaling pathway; Regulation of actin cytoskeleton; Type II diabetes mellitus; Melanoma; Non-small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Colorectal cancer; Renal cell carcinoma; Glioma; Prostate cancer; Pancreatic cancer; ErbB signaling pathway; Endometrial cancer;
BAD	12	VEGF signaling pathway; Focal adhesion; Insulin signaling pathway; Melanoma; Non-small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Colorectal cancer; Prostate cancer; Pancreatic cancer; ErbB signaling pathway; Endometrial cancer;
CCND1	12	Focal adhesion; Melanoma; Bladder cancer; Thyroid cancer; Non-small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Colorectal cancer; Glioma; Prostate cancer; Pancreatic cancer; Endometrial cancer;
MAPK9	10	Focal adhesion; Fc epsilon RI signaling pathway; Toll-like receptor signaling pathway; GnRH signaling pathway; Insulin signaling pathway; Type II diabetes mellitus; MAPK signaling pathway; Colorectal cancer; Pancreatic cancer; ErbB signaling pathway;
GSK3B	8	Axon guidance; Focal adhesion; Melanogenesis; Insulin signaling pathway; Colorectal cancer; Prostate cancer; ErbB signaling pathway; Endometrial cancer;
ERBB2	8	Focal adhesion; Adherens junction; Bladder cancer; Non-small cell lung cancer; Prostate cancer; Pancreatic cancer; ErbB signaling pathway; Endometrial cancer;
PAK1	7	Axon guidance; Focal adhesion; Natural killer cell mediated cytotoxicity; Regulation of actin cytoskeleton; MAPK signaling pathway; Renal cell carcinoma; ErbB signaling pathway;
CRKL	7	Focal adhesion; Insulin signaling pathway; Regulation of actin cytoskeleton; MAPK signaling pathway; Chronic myeloid leukemia; Renal cell carcinoma; ErbB signaling pathway;
VEGFA	6	VEGF signaling pathway; Focal adhesion; mTOR signaling pathway; Bladder cancer; Renal cell carcinoma; Pancreatic cancer;
PLCG2	6	VEGF signaling pathway; Fc epsilon RI signaling pathway; Natural killer cell mediated cytotoxicity; Non-small cell lung cancer; Glioma; ErbB signaling pathway;
SHC3	6	Focal adhesion; Natural killer cell mediated cytotoxicity; Insulin signaling pathway; Chronic myeloid leukemia; Glioma; ErbB signaling pathway;
PDPK1	6	Focal adhesion; mTOR signaling pathway; Insulin signaling pathway; Non-small cell lung cancer; Prostate cancer; Endometrial cancer;
TGFBR1	6	Adherens junction; TGF-beta signaling pathway; MAPK signaling pathway; Chronic myeloid leukemia; Colorectal cancer; Pancreatic cancer;
CREBBP	6	Adherens junction; TGF-beta signaling pathway; Long-term potentiation; Melanogenesis; Renal cell carcinoma; Prostate cancer;
PLA2G6	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PPP3R2	5	VEGF signaling pathway; Axon guidance; Long-term potentiation; Natural killer cell mediated cytotoxicity; MAPK signaling pathway;
PLA2G2D	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G5	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G2E	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G10	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G4B	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G2A	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G1B	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PLA2G3	5	VEGF signaling pathway; Fc epsilon RI signaling pathway; Long-term depression; GnRH signaling pathway; MAPK signaling pathway;
PAK7	5	Axon guidance; Focal adhesion; Regulation of actin cytoskeleton; Renal cell carcinoma; ErbB signaling pathway;
VEGFB	5	Focal adhesion; mTOR signaling pathway; Bladder cancer; Renal cell carcinoma; Pancreatic cancer;
PLCB2	5	Gap junction; Long-term potentiation; Long-term depression; Melanogenesis; GnRH signaling pathway;
PLCB3	5	Gap junction; Long-term potentiation; Long-term depression; Melanogenesis; GnRH signaling pathway;
INS	5	mTOR signaling pathway; Insulin signaling pathway; Regulation of actin cytoskeleton; Type II diabetes mellitus; Prostate cancer;
RPS6KB2	5	mTOR signaling pathway; TGF-beta signaling pathway; Insulin signaling pathway; Acute myeloid leukemia; ErbB signaling pathway;
CAMK2D	5	Long-term potentiation; Melanogenesis; GnRH signaling pathway; Glioma; ErbB signaling pathway;
RELA	5	Toll-like receptor signaling pathway; Chronic myeloid leukemia; Acute myeloid leukemia; Prostate cancer; Pancreatic cancer;
NFATC4	4	VEGF signaling pathway; Axon guidance; Natural killer cell mediated cytotoxicity; MAPK signaling pathway;
ROCK2	4	Axon guidance; Focal adhesion; TGF-beta signaling pathway; Regulation of actin cytoskeleton;
PPP1CA	4	Focal adhesion; Long-term potentiation; Insulin signaling pathway; Regulation of actin cytoskeleton;
PDGFD	4	Focal adhesion; Gap junction; Melanoma; Prostate cancer;
ITPR1	4	Gap junction; Long-term potentiation; Long-term depression; GnRH signaling pathway;
ADCY3	4	Gap junction; Long-term potentiation; Melanogenesis; GnRH signaling pathway;
ITPR2	4	Gap junction; Long-term potentiation; Long-term depression; GnRH signaling pathway;
MAP2K3	4	Fc epsilon RI signaling pathway; Toll-like receptor signaling pathway; GnRH signaling pathway; MAPK signaling pathway;
CACNA1C	4	Long-term potentiation; GnRH signaling pathway; Type II diabetes mellitus; MAPK signaling pathway;
ACTN3	3	Focal adhesion; Adherens junction; Regulation of actin cytoskeleton;
ADCY4	3	Gap junction; Melanogenesis; GnRH signaling pathway;
GRM5	3	Gap junction; Long-term potentiation; Long-term depression;
MAPK7	3	Gap junction; GnRH signaling pathway; MAPK signaling pathway;
ADCY2	3	Gap junction; Melanogenesis; GnRH signaling pathway;
ADCY9	3	Gap junction; Melanogenesis; GnRH signaling pathway;
GRM1	3	Gap junction; Long-term potentiation; Long-term depression;
CACNA1A	3	Long-term depression; Type II diabetes mellitus; MAPK signaling pathway;
CACNA1D	3	GnRH signaling pathway; Type II diabetes mellitus; MAPK signaling pathway;
CBL	3	Insulin signaling pathway; Chronic myeloid leukemia; ErbB signaling pathway;
FGF10	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
FGF3	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
APC	3	Regulation of actin cytoskeleton; Colorectal cancer; Endometrial cancer;
FGF19	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
FGF4	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
FGF9	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
FGF12	3	Regulation of actin cytoskeleton; Melanoma; MAPK signaling pathway;
RASA1	2	Axon guidance; MAPK signaling pathway;
CFL1	2	Axon guidance; Regulation of actin cytoskeleton;
NCK2	2	Axon guidance; ErbB signaling pathway;
NCK1	2	Axon guidance; ErbB signaling pathway;
ARHGEF12	2	Axon guidance; Regulation of actin cytoskeleton;
FLNC	2	Focal adhesion; MAPK signaling pathway;
FN1	2	Focal adhesion; Regulation of actin cytoskeleton;
ITGA11	2	Focal adhesion; Regulation of actin cytoskeleton;
MYLPF	2	Focal adhesion; Regulation of actin cytoskeleton;
ILK	2	Focal adhesion; Endometrial cancer;
ITGA2	2	Focal adhesion; Regulation of actin cytoskeleton;
BCAR1	2	Focal adhesion; Regulation of actin cytoskeleton;
ITGA1	2	Focal adhesion; Regulation of actin cytoskeleton;
CTNNA2	2	Adherens junction; Endometrial cancer;
WASL	2	Adherens junction; Regulation of actin cytoskeleton;
CTNNA3	2	Adherens junction; Endometrial cancer;
TJP1	2	Adherens junction; Gap junction;
BAIAP2	2	Adherens junction; Regulation of actin cytoskeleton;
GUCY1A2	2	Gap junction; Long-term depression;
PRKG1	2	Gap junction; Long-term depression;
MAP2K5	2	Gap junction; MAPK signaling pathway;
PRKAA1	2	mTOR signaling pathway; Insulin signaling pathway;
TSC2	2	mTOR signaling pathway; Insulin signaling pathway;
TSC1	2	mTOR signaling pathway; Insulin signaling pathway;
PPP2R2C	2	TGF-beta signaling pathway; Long-term depression;
PPP2R1B	2	TGF-beta signaling pathway; Long-term depression;
SYK	2	Fc epsilon RI signaling pathway; Natural killer cell mediated cytotoxicity;
GAB2	2	Fc epsilon RI signaling pathway; Chronic myeloid leukemia;
GNAO1	2	Long-term depression; Melanogenesis;
ITGAL	2	Natural killer cell mediated cytotoxicity; Regulation of actin cytoskeleton;
FZD4	2	Melanogenesis; Colorectal cancer;
PLD1	2	GnRH signaling pathway; Pancreatic cancer;
CACNA1S	2	GnRH signaling pathway; MAPK signaling pathway;
CACNA1F	2	GnRH signaling pathway; MAPK signaling pathway;
SOCS1	2	Insulin signaling pathway; Type II diabetes mellitus;
CACNA1G	2	Type II diabetes mellitus; MAPK signaling pathway;
CACNA1B	2	Type II diabetes mellitus; MAPK signaling pathway;
CACNA1E	2	Type II diabetes mellitus; MAPK signaling pathway;
AXIN1	2	Colorectal cancer; Endometrial cancer;

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Region: chr16:30125426..30134827 View in gBrowse