ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol GRIN2A
Previous Symbol NMDAR2A
Symbol Alias GluN2A
Approved Name glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Location 16p13.2
Position chr16:9852376-10276611, -1
External Links HGNC: 4585
Entrez Gene: 2903
Ensembl: ENSG00000183454
UCSC: uc002czo.4
No. of Studies 4 (significant: 1; non-significant: 3; trend: 0)
Source Literature-origin; Mapped by Literature SNP; Mapped by significant region

Gene related studies (count: 4)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Nyman ES, 2007 No evidence of association was seen. Non-significant
Park, S.,2013 There were no significant differences in the genotype or allele frequencies of the GRIN2A rs8049651 polymorphisms between the ADHD and control groups. Non-significant
Turic D, 2004 (a) TRANSMIT genotype analysis: P=0.34 in the initial sample. Overall data of current study suggest that genetic variation in GRIN2A may confer increased risk of ADHD Significant
Adams J, 2004 TRANSMIT analysis, smallest P=0.15, no significant evidence for biased transmission of haplotypes Non-significant

Gene related SNPs (count: 166)

Literature-origin SNPs (count: 10)

LD-proxies (count: 156)


Gene related CNVs (count: 0)

Gene related other variant (count: 4)

Gene related regions (count: 1)

Gene related GO terms (count: 37)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

GO terms by database search (count: 36)


Gene related KEGG pathways (count: 3)

Genes shared at least 5 GO terms with GRIN2A (count: 60)

Genes shared at least 2 KEGG pathways with GRIN2A (count: 37)

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Region: chr16:9852376..10276611 View in gBrowse
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