ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0001975
Name response to amphetamine
Type biological process
No. of Genes in ADHDgene  16
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 16)

Literature-origin genes (count: 14)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) IEA
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17q12 1(0/1/0) IEA
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) ISS
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0) IEA
DRD1 dopamine receptor D1 5q34-q35 8(5/3/0) IEA
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 2(0/2/0) IEA
ADRA1B adrenoceptor alpha 1B 5q33.3 2(1/1/0) IEA
OXTR oxytocin receptor 3p25 1(0/1/0) IEA
DRD5 dopamine receptor D5 4p16.1 22(14/6/2) IEA
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IEA
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IEA
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) IEA

Genes from other sources Help (count: 2)

Approved Symbol Approved Name Source Evidence[PMID]
ADORA2A adenosine A2a receptor Mapped by CNV IEA
TRDMT1 tRNA aspartic acid methyltransferase 1 Mapped by CNV IEA