ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol HTR3B
Symbol Alias 5-HT3B
Approved Name 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Previous Name "5-hydroxytryptamine (serotonin) receptor 3B"
Location 11q23.1
Position chr11:113775399-113817287, 1
External Links HGNC: 5298
Entrez Gene: 9177
Ensembl: ENSG00000149305
UCSC: uc001pok.3
No. of Studies 3 (significant: 1; non-significant: 2; trend: 0)
Source Literature-origin; Mapped by Literature SNP; Mapped by significant region

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Ribases M, 2009(b) little evidence of association with ADHD was found. Non-significant
Brookes K, 2006 UNPHASED TDT P-value=0.121, global P-value=0.778, WHAP TDT P_sum P-value=0.81, no SNP with nominal P-value<0.05 located in this gene Non-significant
Oades RD, 2008 2 SNPs showed significant association Significant

Gene related SNPs (count: 6)

Literature-origin SNPs (count: 2)

LD-proxies (count: 4)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)


Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HTR3B (count: 12)

Genes shared at least 2 KEGG pathways with HTR3B (count: 0)

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Region: chr11:113775399..113817287 View in gBrowse
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