ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol GRIN2B
Previous Symbol NMDAR2B
Symbol Alias GluN2B
Approved Name glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Location 12p12
Position chr12:13693165-14133053, -1
External Links HGNC: 4586
Entrez Gene: 2904
Ensembl: ENSG00000150086
UCSC: uc001rbt.2
No. of Studies 2 (significant: 1; non-significant: 1; trend: 0)
Source Literature-origin

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Park, S.,2013 There were no significant differences in the genotype or allele frequencies of the GRIN2B rs2284411 polymorphisms between the ADHD and control groups. Non-significant
Dorval KM, 2007 In haplotype analysis, the most significant P-value=0.013 . The global transmit results were significant for haplotypes with a frequency greater than 10%(P-value=0.008) and for all haplotypes(P-value=0.003). Significant

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 32)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

GO terms by database search (count: 31)


Gene related KEGG pathways (count: 3)

Genes shared at least 5 GO terms with GRIN2B (count: 50)

Genes shared at least 2 KEGG pathways with GRIN2B (count: 4)

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Region: chr12:13693165..14133053 View in gBrowse
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