ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043005
Name neuron projection
Type cellular component
No. of Genes in ADHDgene  38
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 16)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ITGA1 integrin, alpha 1 5q11.1 2(0/2/0) IEA
TENM4 teneurin transmembrane protein 4 11q13 1(0/1/0) ISS
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 2(1/1/0) ISS
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0) IEA
TPH2 tryptophan hydroxylase 2 12q15 11(8/3/0) IEA
NRSN1 neurensin 1 6p22.1 1(1/0/0) ISS
CDH13 cadherin 13 16q23.3 4(1/2/1) IDA[10737605]
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IDA[17135716]
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) ISS
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 17q11.2 26(13/13/0) IEA
SNPH syntaphilin 20p13 1(1/0/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) IEA
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) IEA
STX1A syntaxin 1A (brain) 7q11.2 3(2/1/0) IDA[12115694]
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 2(0/2/0) IEA
TPH1 tryptophan hydroxylase 1 11p15.3-p14 6(2/4/0) IEA

Genes from other sources Help (count: 22)

Approved Symbol Approved Name Source Evidence[PMID]
RNF40 ring finger protein 40, E3 ubiquitin protein ligase Mapped by CNV ISS
CYFIP1 cytoplasmic FMR1 interacting protein 1 Mapped by significant region ISS
SYT4 synaptotagmin IV Mapped by significant region IEA
MYO10 myosin X Mapped by significant region IEA
DOC2A double C2-like domains, alpha Mapped by CNV IEA
KLHL14 kelch-like family member 14 Mapped by significant region IEA
ARG1 arginase 1 Mapped by significant region IEA
ABAT 4-aminobutyrate aminotransferase Mapped by significant region IEA
FADD Fas (TNFRSF6)-associated via death domain Mapped by significant region IEA
KLC2 kinesin light chain 2 Mapped by significant region IEA
STX3 syntaxin 3 Mapped by significant region ISS
MARK4 MAP/microtubule affinity-regulating kinase 4 Mapped by PBA pathway IDA[14594945]
SNAP23 synaptosomal-associated protein, 23kDa Mapped by PBA pathway IEA
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Mapped by significant region IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IDA[17658481]
CTSV cathepsin V Mapped by significant region IEA
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region IEA
CYFIP2 cytoplasmic FMR1 interacting protein 2 Mapped by significant region IEA
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region ISS
FOSL1 FOS-like antigen 1 Mapped by significant region IEA
SNAP29 synaptosomal-associated protein, 29kDa Mapped by CNV IEA
CACYBP calcyclin binding protein Mapped by significant region IEA