ADHDgene Database

SNP Report

Basic Info

Name	rs2284411 dbSNP Ensembl
Location	chr12:13866172(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000609686)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Dorval KM, 2007	T/C	C	Allelic TDT P-value=0.005 Allelic TDT P-value=0.005	Significant TDT results Significant TDT results	Significant
Park, S.,2013	C/T		allelic P-value=0.281 (Cohen`s w=0.04;X²=1.16);ge...... allelic P-value=0.281 (Cohen`s w=0.04;X²=1.16);genotypic P-value=0.469 (Cohen`s w=0.06;X²=1.52);TDT P-value=0.331,Cohen`s w=0.06, X²=0.94. More...	This SNP was not significant associated with ADHD This SNP was not significant associated with ADHD	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	12p12	2(1/1/0)

SNPs in LD with rs2284411 (count: 10) View in gBrowse (chr12:13857007..13872044 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.