ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	GOPC
Symbol Alias	dJ94G16.2, PIST, FIG, GOPC1, CAL
Approved Name	golgi-associated PDZ and coiled-coil motif containing
Location	6q21
Position	chr6:117639374-117923705, -
External Links	HGNC: 17643 Entrez Gene: 57120 Ensembl: ENSG00000047932
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 23)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 23)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007289	spermatid nucleus differentiation	Biological Process		3
GO:0008022	protein C-terminus binding	Molecular Function		32
GO:0014069	postsynaptic density	Cellular Component		23
GO:0015031	protein transport	Biological Process		75
GO:0016020	membrane	Cellular Component	IDA[11707463]	139
GO:0030054	cell junction	Cellular Component		77
GO:0030140	trans-Golgi network transport vesicle	Cellular Component	IDA[11707463]; NAS[11384996]	7
GO:0042803	protein homodimerization activity	Molecular Function		113
GO:0043004	cytoplasmic sequestering of CFTR protein	Biological Process	NAS[11707463]	1
GO:0043234	protein complex	Cellular Component	IDA[18468998]	45
GO:0044325	ion channel binding	Molecular Function	IPI[11707463]	15
GO:0045176	apical protein localization	Biological Process	NAS[11707463]	4
GO:0045211	postsynaptic membrane	Cellular Component		41
GO:0051260	protein homooligomerization	Biological Process	IPI[11707463]	34
GO:0000139	Golgi membrane	Cellular Component		95
GO:0005109	frizzled binding	Molecular Function		3
GO:0005083	small GTPase regulator activity	Molecular Function		5
GO:0005737	cytoplasm	Cellular Component		690
GO:0005515	protein binding	Molecular Function	IPI[11707463]	910
GO:0005886	plasma membrane	Cellular Component	NAS[11707463]	772
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0006893	Golgi to plasma membrane transport	Biological Process	NAS[11707463]	3
GO:0006888	ER to Golgi vesicle-mediated transport	Biological Process	NAS[11707463]	24

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GOPC (count: 33)

Gene Symbol	Pathway Count	Pathway List
ACHE	7	membrane; cell junction; protein homodimerization activity; postsynaptic membrane; protein binding; plasma membrane; Golgi apparatus;
CORO1A	6	protein C-terminus binding; protein homodimerization activity; protein complex; cytoplasm; protein binding; plasma membrane;
ARHGAP32	6	postsynaptic density; cell junction; postsynaptic membrane; Golgi membrane; protein binding; plasma membrane;
ARRB2	6	postsynaptic density; protein transport; postsynaptic membrane; cytoplasm; protein binding; plasma membrane;
SHANK2	6	postsynaptic density; cell junction; postsynaptic membrane; cytoplasm; protein binding; plasma membrane;
CRYAB	6	protein homodimerization activity; protein homooligomerization; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
BAIAP2	5	protein C-terminus binding; cell junction; cytoplasm; protein binding; plasma membrane;
CAV3	5	protein C-terminus binding; ion channel binding; Golgi membrane; protein binding; plasma membrane;
TJP1	5	protein C-terminus binding; cell junction; cytoplasm; protein binding; plasma membrane;
ADORA2A	5	postsynaptic density; membrane; postsynaptic membrane; protein binding; plasma membrane;
CHRM1	5	postsynaptic density; membrane; cell junction; postsynaptic membrane; plasma membrane;
DLG2	5	postsynaptic density; cell junction; postsynaptic membrane; protein binding; plasma membrane;
GRIN2A	5	postsynaptic density; cell junction; postsynaptic membrane; protein binding; plasma membrane;
GRIN2B	5	postsynaptic density; cell junction; postsynaptic membrane; protein binding; plasma membrane;
GRIN3A	5	postsynaptic density; membrane; cell junction; postsynaptic membrane; protein binding;
ARF6	5	protein transport; membrane; protein binding; plasma membrane; Golgi apparatus;
ARRB1	5	protein transport; Golgi membrane; cytoplasm; protein binding; plasma membrane;
GABARAPL2	5	protein transport; Golgi membrane; cytoplasm; protein binding; Golgi apparatus;
RAB14	5	protein transport; trans-Golgi network transport vesicle; Golgi membrane; protein binding; plasma membrane;
SNAP23	5	protein transport; cell junction; protein binding; plasma membrane; Golgi apparatus;
YKT6	5	protein transport; Golgi membrane; cytoplasm; Golgi apparatus; ER to Golgi vesicle-mediated transport;
RYR2	5	membrane; protein complex; ion channel binding; protein binding; plasma membrane;
SNAP25	5	membrane; cell junction; cytoplasm; protein binding; plasma membrane;
SYTL2	5	membrane; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
DTNA	5	cell junction; protein complex; cytoplasm; protein binding; plasma membrane;
RAPSN	5	cell junction; postsynaptic membrane; cytoplasm; plasma membrane; Golgi apparatus;
SNCA	5	cell junction; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
TMED10	5	trans-Golgi network transport vesicle; protein binding; plasma membrane; Golgi apparatus; ER to Golgi vesicle-mediated transport;
CEP57	5	protein homodimerization activity; protein homooligomerization; cytoplasm; protein binding; Golgi apparatus;
PDE2A	5	protein homodimerization activity; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
PAK1	5	protein complex; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
STRN3	5	protein complex; cytoplasm; protein binding; plasma membrane; Golgi apparatus;
COG3	5	cytoplasm; protein binding; plasma membrane; Golgi apparatus; ER to Golgi vesicle-mediated transport;

Genes shared at least 2 KEGG pathways with GOPC (count: 0)

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Region: chr6:117639374..117923705 View in gBrowse