ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SYTL2
Symbol Alias	FLJ20163, FLJ21219, KIAA1597, exophilin-4, CHR11SYT, SLP2, SGA72M, MGC102768
Approved Name	synaptotagmin-like 2
Name Alias	chromosome 11 synaptotagmin, "breast cancer-associated antigen SGA-72M"
Location	11
Position	chr11:85405264-85522184, -
External Links	HGNC: 15585 Entrez Gene: 54843 Ensembl: ENSG00000137501 UCSC: uc001pbb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 19)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 19)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Molecular Function	IMP[17182843]	4
GO:0005515	protein binding	Molecular Function	IPI[18940603]	910
GO:0001786	phosphatidylserine binding	Molecular Function	IMP[17182843]	3
GO:0005737	cytoplasm	Cellular Component		690
GO:0005634	nucleus	Cellular Component		770
GO:0005886	plasma membrane	Cellular Component		772
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0006887	exocytosis	Biological Process	IDA[18812475]	14
GO:0006886	intracellular protein transport	Biological Process		43
GO:0010923	negative regulation of phosphatase activity	Biological Process	IDA[19389623]	8
GO:0006904	vesicle docking involved in exocytosis	Biological Process	IDA[18812475]	8
GO:0016192	vesicle-mediated transport	Biological Process		28
GO:0016020	membrane	Cellular Component		139
GO:0019897	extrinsic to plasma membrane	Cellular Component		3
GO:0017137	Rab GTPase binding	Molecular Function		8
GO:0042043	neurexin family protein binding	Molecular Function		2
GO:0019902	phosphatase binding	Molecular Function	IDA[19389623]	5
GO:0042470	melanosome	Cellular Component		22
GO:0070382	exocytic vesicle	Cellular Component	IDA[18812475]	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SYTL2 (count: 18)

Gene Symbol	Pathway Count	Pathway List
COG3	6	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus; intracellular protein transport;
ACHE	5	protein binding; nucleus; plasma membrane; Golgi apparatus; membrane;
ARF6	5	protein binding; plasma membrane; Golgi apparatus; vesicle-mediated transport; membrane;
BICD2	5	protein binding; cytoplasm; plasma membrane; Golgi apparatus; Rab GTPase binding;
CRYAB	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;
GOPC	5	protein binding; cytoplasm; plasma membrane; Golgi apparatus; membrane;
MAGI2	5	protein binding; cytoplasm; nucleus; plasma membrane; phosphatase binding;
MAPK1	5	protein binding; cytoplasm; nucleus; Golgi apparatus; phosphatase binding;
PAK1	5	protein binding; cytoplasm; plasma membrane; Golgi apparatus; exocytosis;
PDE2A	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;
PRKD1	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;
RAB27A	5	protein binding; Golgi apparatus; exocytosis; melanosome; exocytic vesicle;
SNAP23	5	protein binding; nucleus; plasma membrane; Golgi apparatus; exocytosis;
SNCA	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;
STRN3	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;
STXBP3	5	protein binding; cytoplasm; nucleus; plasma membrane; vesicle docking involved in exocytosis;
TMED10	5	protein binding; plasma membrane; Golgi apparatus; intracellular protein transport; melanosome;
WWOX	5	protein binding; cytoplasm; nucleus; plasma membrane; Golgi apparatus;

Genes shared at least 2 KEGG pathways with SYTL2 (count: 0)

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Region: chr11:85405264..85522184 View in gBrowse