ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	YKT6
Approved Name	YKT6 v-SNARE homolog (S. cerevisiae)
Name Alias	R-SNARE
Location	7p13
Position	chr7:44240567-44253893, +
External Links	HGNC: 16959 Entrez Gene: 10652 Ensembl: ENSG00000106636 UCSC: uc003tkm.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005739	mitochondrion	Cellular Component		183
GO:0005768	endosome	Cellular Component	IDA[15215310]	27
GO:0005783	endoplasmic reticulum	Cellular Component	IDA[9211930]	100
GO:0005794	Golgi apparatus	Cellular Component	IDA[15215310]	157
GO:0005829	cytosol	Cellular Component		447
GO:0005887	integral to plasma membrane	Cellular Component	IDA[9211930]	220
GO:0006888	ER to Golgi vesicle-mediated transport	Biological Process	IDA[9211930]	24
GO:0006903	vesicle targeting	Biological Process	IDA[9211930]	5
GO:0000139	Golgi membrane	Cellular Component		95
GO:0005484	SNAP receptor activity	Molecular Function	IDA[15215310]	13
GO:0005737	cytoplasm	Cellular Component		690
GO:0015031	protein transport	Biological Process		75
GO:0006904	vesicle docking involved in exocytosis	Biological Process	IDA[9211930]	8
GO:0030659	cytoplasmic vesicle membrane	Cellular Component		18
GO:0019706	protein-cysteine S-palmitoleyltransferase activity	Molecular Function	IDA[15479160]	1
GO:0042147	retrograde transport, endosome to Golgi	Biological Process	IDA[15215310]	5
GO:0031201	SNARE complex	Cellular Component	TAS[15215310]	13

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04130	SNARE interactions in vesicular transport	20

Genes shared at least 5 GO terms with YKT6 (count: 13)

Gene Symbol	Pathway Count	Pathway List
STX5	8	endoplasmic reticulum; Golgi apparatus; ER to Golgi vesicle-mediated transport; vesicle targeting; Golgi membrane; SNAP receptor activity; retrograde transport, endosome to Golgi; SNARE complex;
GOSR1	8	Golgi apparatus; ER to Golgi vesicle-mediated transport; Golgi membrane; SNAP receptor activity; protein transport; retrograde transport, endosome to Golgi; SNARE complex; Golgi vesicle transport;
STX16	7	Golgi apparatus; Golgi membrane; SNAP receptor activity; cytoplasm; retrograde transport, endosome to Golgi; SNARE complex; Golgi vesicle transport;
STX6	6	Golgi apparatus; Golgi membrane; SNAP receptor activity; retrograde transport, endosome to Golgi; SNARE complex; Golgi vesicle transport;
PARK2	5	mitochondrion; endoplasmic reticulum; Golgi apparatus; cytosol; cytoplasm;
BACE1	5	endosome; endoplasmic reticulum; Golgi apparatus; integral to plasma membrane; cytoplasmic vesicle membrane;
STX18	5	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; Golgi membrane; SNAP receptor activity; Golgi vesicle transport;
ZW10	5	endoplasmic reticulum; cytosol; ER to Golgi vesicle-mediated transport; protein transport; Golgi vesicle transport;
GABARAPL2	5	Golgi apparatus; cytosol; Golgi membrane; cytoplasm; protein transport;
GOPC	5	Golgi apparatus; ER to Golgi vesicle-mediated transport; Golgi membrane; cytoplasm; protein transport;
LMAN2L	5	Golgi apparatus; ER to Golgi vesicle-mediated transport; Golgi membrane; protein transport; Golgi vesicle transport;
PRKD1	5	Golgi apparatus; cytosol; integral to plasma membrane; cytoplasm; Golgi vesicle transport;
ARRB1	5	cytosol; Golgi membrane; cytoplasm; protein transport; cytoplasmic vesicle membrane;

Genes shared at least 2 KEGG pathways with YKT6 (count: 0)

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Region: chr7:44240567..44253893 View in gBrowse