ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	STX5
Previous Symbol	STX5A
Symbol Alias	SED5
Approved Name	syntaxin 5
Previous Name	syntaxin 5A
Location	11q12.3
Position	chr11:62574369-62599560, -
External Links	HGNC: 11440 Entrez Gene: 6811 Ensembl: ENSG00000162236 UCSC: uc001nvh.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048280	vesicle fusion with Golgi apparatus	Biological Process		3
GO:0042147	retrograde transport, endosome to Golgi	Biological Process	IDA[15215310]	5
GO:0047485	protein N-terminus binding	Molecular Function	IPI[19536132]	23
GO:0031201	SNARE complex	Cellular Component	TAS[15215310]	13
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular Component		10
GO:0006903	vesicle targeting	Biological Process	TAS[9188044]	5
GO:0016021	integral to membrane	Cellular Component		845
GO:0006886	intracellular protein transport	Biological Process		43
GO:0006888	ER to Golgi vesicle-mediated transport	Biological Process		24
GO:0005783	endoplasmic reticulum	Cellular Component		100
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0000139	Golgi membrane	Cellular Component		95
GO:0005484	SNAP receptor activity	Molecular Function	IDA[15215310]	13

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04130	SNARE interactions in vesicular transport	20

Genes shared at least 5 GO terms with STX5 (count: 11)

Gene Symbol	Pathway Count	Pathway List
STX16	8	retrograde transport, endosome to Golgi; SNARE complex; integral to membrane; intracellular protein transport; Golgi apparatus; nucleolus; Golgi membrane; SNAP receptor activity;
YKT6	8	retrograde transport, endosome to Golgi; SNARE complex; vesicle targeting; ER to Golgi vesicle-mediated transport; endoplasmic reticulum; Golgi apparatus; Golgi membrane; SNAP receptor activity;
GOSR1	7	retrograde transport, endosome to Golgi; SNARE complex; integral to membrane; ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi membrane; SNAP receptor activity;
STX6	7	retrograde transport, endosome to Golgi; SNARE complex; integral to membrane; intracellular protein transport; Golgi apparatus; Golgi membrane; SNAP receptor activity;
TMED10	6	endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; intracellular protein transport; ER to Golgi vesicle-mediated transport; endoplasmic reticulum; Golgi apparatus;
TMED2	6	endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; intracellular protein transport; ER to Golgi vesicle-mediated transport; endoplasmic reticulum; Golgi apparatus;
STX18	6	integral to membrane; intracellular protein transport; ER to Golgi vesicle-mediated transport; endoplasmic reticulum; Golgi membrane; SNAP receptor activity;
STX1A	5	protein N-terminus binding; SNARE complex; integral to membrane; intracellular protein transport; SNAP receptor activity;
STX17	5	SNARE complex; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; intracellular protein transport; SNAP receptor activity;
FKTN	5	integral to membrane; endoplasmic reticulum; Golgi apparatus; nucleus; Golgi membrane;
COG3	5	intracellular protein transport; ER to Golgi vesicle-mediated transport; Golgi apparatus; nucleus; nucleolus;

Genes shared at least 2 KEGG pathways with STX5 (count: 0)

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Region: chr11:62574369..62599560 View in gBrowse