ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005730
Name nucleolus
Type cellular component
No. of Genes in ADHDgene  271
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 271)

Literature-origin genes (count: 19)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ATXN1 ataxin 1 6p23 1(0/0/1) IDA
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) IDA
ATXN2 ataxin 2 12q23-q24.1 1(0/0/1) IDA
HKDC1 hexokinase domain containing 1 10q22.1 1(0/1/0) IDA
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) IDA
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 2(2/0/0) IDA
HOXB1 homeobox B1 17q21.32 1(0/0/1) IDA
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) IDA
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 1(0/0/1) IDA
MED27 mediator complex subunit 27 9q34.13 1(0/1/0) IDA
CLOCK clock circadian regulator 4q12 2(2/0/0) IDA
XPO1 exportin 1 2p15 1(0/0/1) IEA
NPAS3 neuronal PAS domain protein 3 14q13.1 1(1/0/0) IDA
FOXP1 forkhead box P1 3p14.1 1(0/0/1) IDA
TDP2 tyrosyl-DNA phosphodiesterase 2 6p22.3-p22.1 1(0/1/0) IEA
PHLDA1 pleckstrin homology-like domain, family A, member 1 12q15 1(0/1/0) IDA
HK1 hexokinase 1 10q22 1(0/1/0) IDA
GPRC5B G protein-coupled receptor, class C, group 5, member B 16p12 1(1/0/0) IDA
MOBP myelin-associated oligodendrocyte basic protein 3p21.33 1(0/0/1) IDA

Genes from other sources Help (count: 252)

Approved Symbol Approved Name Source Evidence[PMID]
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mapped by CNV; Mapped by significant region IDA
TCF25 transcription factor 25 (basic helix-loop-helix) Mapped by significant region IDA
MPHOSPH6 M-phase phosphoprotein 6 Mapped by significant region IDA
MIDN midnolin Mapped by CNV IEA
TMEM109 transmembrane protein 109 Mapped by significant region IDA
USP28 ubiquitin specific peptidase 28 Mapped by significant region IDA; IDA
INIP INTS3 and NABP interacting protein Mapped by significant region IDA
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) Mapped by significant region IDA
SPATA13 spermatogenesis associated 13 Mapped by Literature SNP; Mapped by CNV IDA
CDC14B cell division cycle 14B Mapped by significant region IDA[18662541]
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway IDA
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IDA[16387653]; IDA
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) Mapped by CNV; Mapped by significant region IDA
MPHOSPH8 M-phase phosphoprotein 8 Mapped by significant region IDA
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 Mapped by significant region IEA
C16orf46 chromosome 16 open reading frame 46 Mapped by significant region IDA
IMP4 IMP4, U3 small nucleolar ribonucleoprotein Mapped by significant region IDA[12655004]
RILPL1 Rab interacting lysosomal protein-like 1 Mapped by CNV IDA
POLD3 polymerase (DNA-directed), delta 3, accessory subunit Mapped by significant region IDA
TSPYL1 TSPY-like 1 Mapped by significant region IDA
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) Mapped by CNV; Mapped by significant region IDA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IDA
BRIX1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) Mapped by significant region IDA
HINFP histone H4 transcription factor Mapped by significant region IDA[11553631]
ZBTB9 zinc finger and BTB domain containing 9 Mapped by LD-proxy IDA
KATNBL1 katanin p80 subunit B-like 1 Mapped by CNV IDA
BCAS2 breast carcinoma amplified sequence 2 Mapped by PBA pathway IEA
NCOR2 nuclear receptor corepressor 2 Mapped by CNV IDA
NUMA1 nuclear mitotic apparatus protein 1 Mapped by significant region IDA
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) Mapped by CNV IDA
NOL10 nucleolar protein 10 Mapped by significant region IEA
MUS81 MUS81 structure-specific endonuclease subunit Mapped by significant region IEA
ELP2 elongator acetyltransferase complex subunit 2 Mapped by significant region IC[11714725]
RNF2 ring finger protein 2 Mapped by significant region IDA
CELF4 CUGBP, Elav-like family member 4 Mapped by significant region IDA
ZNF263 zinc finger protein 263 Mapped by LD-proxy; Mapped by significant region IDA
NCL nucleolin Mapped by Literature SNP IDA
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 Mapped by PBA pathway IDA
POU2F3 POU class 2 homeobox 3 Mapped by significant region IDA
TRIM66 tripartite motif containing 66 Mapped by LD-proxy IDA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region IDA
RNF40 ring finger protein 40, E3 ubiquitin protein ligase Mapped by CNV IDA
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 Mapped by significant region IEA
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) Mapped by CNV IDA
KLHL7 kelch-like family member 7 Mapped by significant region IDA; IDA
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 Mapped by PBA pathway IDA; IDA
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 Mapped by significant region IDA
TNR tenascin R Mapped by significant region IDA
PARN poly(A)-specific ribonuclease Mapped by significant region IEA
RPS2 ribosomal protein S2 Mapped by significant region IDA[16263090]
BSPRY B-box and SPRY domain containing Mapped by significant region IDA
VWA5A von Willebrand factor A domain containing 5A Mapped by significant region IDA
RBM4B RNA binding motif protein 4B Mapped by significant region IEA
TSEN15 TSEN15 tRNA splicing endonuclease subunit Mapped by significant region IEA
MTA2 metastasis associated 1 family, member 2 Mapped by significant region IDA
ALKBH8 alkB, alkylation repair homolog 8 (E. coli) Mapped by significant region IDA
RAB11FIP3 RAB11 family interacting protein 3 (class II) Mapped by significant region IDA
CENPW centromere protein W Mapped by significant region IEA
MTA3 metastasis associated 1 family, member 3 Mapped by Literature SNP IDA
RBM14 RNA binding motif protein 14 Mapped by significant region IDA
APRT adenine phosphoribosyltransferase Mapped by significant region IDA
COG3 component of oligomeric golgi complex 3 Mapped by PBA pathway IDA
SAP18 Sin3A-associated protein, 18kDa Mapped by significant region IDA
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 Mapped by significant region IDA
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) Mapped by CNV IDA
DPF2 D4, zinc and double PHD fingers family 2 Mapped by significant region IDA
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) Mapped by significant region IDA
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) Mapped by significant region IDA
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa Mapped by significant region IDA; IDA
PRPF4 pre-mRNA processing factor 4 Mapped by significant region IDA
NMRAL1 NmrA-like family domain containing 1 Mapped by significant region IDA
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway IDA
HOXA3 homeobox A3 Mapped by significant region IDA
U2AF1 U2 small nuclear RNA auxiliary factor 1 Mapped by PBA pathway IDA
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region IDA
RPL35 ribosomal protein L35 Mapped by significant region TAS[2891103]
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) Mapped by significant region IDA
AATF apoptosis antagonizing transcription factor Mapped by CNV IDA
NCF2 neutrophil cytosolic factor 2 Mapped by significant region IDA
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region IDA
HSF2 heat shock transcription factor 2 Mapped by significant region IDA
NEK4 NIMA-related kinase 4 Mapped by LD-proxy IDA
SART1 squamous cell carcinoma antigen recognized by T cells Mapped by significant region IDA
BCLAF1 BCL2-associated transcription factor 1 Mapped by significant region IDA; IDA
FNBP4 formin binding protein 4 Mapped by LD-proxy IDA
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV IDA
FHOD3 formin homology 2 domain containing 3 Mapped by significant region IDA
SF3B2 splicing factor 3b, subunit 2, 145kDa Mapped by significant region; Mapped by PBA pathway IDA
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region IDA
TEX10 testis expressed 10 Mapped by significant region IEA
NOL8 nucleolar protein 8 Mapped by significant region IDA
SRP19 signal recognition particle 19kDa Mapped by LD-proxy IDA[10618370]
TUBGCP2 tubulin, gamma complex associated protein 2 Mapped by Literature SNP; Mapped by CNV; Mapped by PBA pathway IDA
ATF7IP2 activating transcription factor 7 interacting protein 2 Mapped by significant region IDA
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme Mapped by significant region IEA
RAD23B RAD23 homolog B (S. cerevisiae) Mapped by significant region IDA
YPEL3 yippee-like 3 (Drosophila) Mapped by CNV IEA
CRBN cereblon Mapped by CNV IDA
RBMXL2 RNA binding motif protein, X-linked-like 2 Mapped by CNV IDA
RPS9 ribosomal protein S9 Mapped by CNV IDA[18420587]
HYLS1 hydrolethalus syndrome 1 Mapped by significant region IDA
CABIN1 calcineurin binding protein 1 Mapped by CNV IDA
TMUB1 transmembrane and ubiquitin-like domain containing 1 Mapped by Literature SNP IDA
FEN1 flap structure-specific endonuclease 1 Mapped by Literature SNP; Mapped by significant region IEA
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) Mapped by LD-proxy IDA
HOXA11 homeobox A11 Mapped by significant region IDA
ZFP91 ZFP91 zinc finger protein Mapped by significant region IDA
OSBPL1A oxysterol binding protein-like 1A Mapped by significant region IDA
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific Mapped by significant region IDA[16790842]
SNAP29 synaptosomal-associated protein, 29kDa Mapped by CNV IDA
AIP aryl hydrocarbon receptor interacting protein Mapped by significant region IDA
NOL4 nucleolar protein 4 Mapped by significant region IEA
SF3A3 splicing factor 3a, subunit 3, 60kDa Mapped by PBA pathway IDA
FLYWCH1 FLYWCH-type zinc finger 1 Mapped by significant region IDA
PHF2 PHD finger protein 2 Mapped by significant region IDA
SRRM2 serine/arginine repetitive matrix 2 Mapped by significant region IDA
ZNF622 zinc finger protein 622 Mapped by significant region IDA
GPSM2 G-protein signaling modulator 2 Mapped by CNV IDA
ZEB2 zinc finger E-box binding homeobox 2 Mapped by PBA pathway IDA
TBL3 transducin (beta)-like 3 Mapped by significant region IDA
PSPC1 paraspeckle component 1 Mapped by significant region IDA; IDA
ALAS1 aminolevulinate, delta-, synthase 1 Mapped by LD-proxy IDA
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) Mapped by CNV IEA
NMD3 NMD3 ribosome export adaptor Mapped by CNV IDA
MED4 mediator complex subunit 4 Mapped by PBA pathway IDA
HSPA8 heat shock 70kDa protein 8 Mapped by significant region IDA
ZMAT5 zinc finger, matrin-type 5 Mapped by PBA pathway IDA
GATAD2A GATA zinc finger domain containing 2A Mapped by LD-proxy IDA
INO80E INO80 complex subunit E Mapped by CNV IDA
TAOK2 TAO kinase 2 Mapped by CNV IDA
DCPS decapping enzyme, scavenger Mapped by significant region IDA
REXO2 RNA exonuclease 2 Mapped by significant region IDA
RCC1 regulator of chromosome condensation 1 Mapped by PBA pathway IDA
STX16 syntaxin 16 Mapped by PBA pathway IDA
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) Mapped by CNV IDA
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 Mapped by CNV; Mapped by significant region; Mapped by PBA pathway IDA
ZNF74 zinc finger protein 74 Mapped by CNV IDA
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 Mapped by CNV; Mapped by PBA pathway IEA
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 Mapped by LD-proxy IDA
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV IDA; IDA
SNAP23 synaptosomal-associated protein, 23kDa Mapped by PBA pathway IDA
SNX15 sorting nexin 15 Mapped by significant region IDA
SLU7 SLU7 splicing factor homolog (S. cerevisiae) Mapped by significant region; Mapped by PBA pathway IDA
PHF7 PHD finger protein 7 Mapped by LD-proxy IDA
DROSHA drosha, ribonuclease type III Mapped by significant region IEA
ZBTB20 zinc finger and BTB domain containing 20 Mapped by LD-proxy IDA
DGCR8 DGCR8 microprocessor complex subunit Mapped by CNV IDA
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) Mapped by significant region IDA; IDA
PNN pinin, desmosome associated protein Mapped by LD-proxy IDA
BYSL bystin-like Mapped by CNV IDA
IGFALS insulin-like growth factor binding protein, acid labile subunit Mapped by significant region IDA
TACC2 transforming, acidic coiled-coil containing protein 2 Mapped by PBA pathway IDA
RBM4 RNA binding motif protein 4 Mapped by significant region IDA[12628928]
CDK12 cyclin-dependent kinase 12 Mapped by LD-proxy IDA
SCAF8 SR-related CTD-associated factor 8 Mapped by Literature SNP IDA
RAD1 RAD1 homolog (S. pombe) Mapped by significant region IDA
FAM129A family with sequence similarity 129, member A Mapped by significant region IDA
ZNF77 zinc finger protein 77 Mapped by CNV IDA
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV IDA
SUB1 SUB1 homolog (S. cerevisiae) Mapped by significant region IDA
ZFR zinc finger RNA binding protein Mapped by significant region IDA
RNF20 ring finger protein 20, E3 ubiquitin protein ligase Mapped by significant region IDA[19037095]
PERP PERP, TP53 apoptosis effector Mapped by significant region IDA
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway IDA[12466272]
CRYM crystallin, mu Mapped by significant region IDA
PRC1 protein regulator of cytokinesis 1 Mapped by PBA pathway IDA
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region IDA[11714725]
TRIM5 tripartite motif containing 5 Mapped by CNV IDA
COG5 component of oligomeric golgi complex 5 Mapped by CNV IDA
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 Mapped by significant region IDA[17071714]
CCDC86 coiled-coil domain containing 86 Mapped by significant region IDA
API5 apoptosis inhibitor 5 Mapped by PBA pathway IDA
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa Mapped by CNV IDA
YPEL4 yippee-like 4 (Drosophila) Mapped by significant region IEA
FUS fused in sarcoma Mapped by CNV IDA
HOXA2 homeobox A2 Mapped by significant region IDA
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway IDA
SERGEF secretion regulating guanine nucleotide exchange factor Mapped by LD-proxy IDA
MEN1 multiple endocrine neoplasia I Mapped by significant region IDA
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 Mapped by significant region IDA
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV IDA
SETD1A SET domain containing 1A Mapped by CNV IDA
FLII flightless I homolog (Drosophila) Mapped by significant region IDA
THRSP thyroid hormone responsive Mapped by significant region IDA
CEP164 centrosomal protein 164kDa Mapped by significant region IDA
AP3B2 adaptor-related protein complex 3, beta 2 subunit Mapped by PBA pathway IDA
INO80C INO80 complex subunit C Mapped by significant region IDA
ZC3H18 zinc finger CCCH-type containing 18 Mapped by significant region IDA
G2E3 G2/M-phase specific E3 ubiquitin protein ligase Mapped by significant region IEA
DPP3 dipeptidyl-peptidase 3 Mapped by significant region IDA
TERT telomerase reverse transcriptase Mapped by significant region IEA
ELMOD1 ELMO/CED-12 domain containing 1 Mapped by significant region IDA
KNOP1 lysine-rich nucleolar protein 1 Mapped by significant region IEA
CDCA5 cell division cycle associated 5 Mapped by significant region IDA
SCAMP2 secretory carrier membrane protein 2 Mapped by PBA pathway IDA
SUGP1 SURP and G patch domain containing 1 Mapped by LD-proxy IDA
KRT18 keratin 18 Mapped by PBA pathway IEA
SDHAF2 succinate dehydrogenase complex assembly factor 2 Mapped by significant region IDA
CAPG capping protein (actin filament), gelsolin-like Mapped by PBA pathway IDA; IDA
FOXD4 forkhead box D4 Mapped by CNV IDA
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway IDA
POLA2 polymerase (DNA directed), alpha 2, accessory subunit Mapped by significant region IDA
VPS9D1 VPS9 domain containing 1 Mapped by significant region IDA
SYVN1 synovial apoptosis inhibitor 1, synoviolin Mapped by significant region IDA
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) Mapped by LD-proxy IDA
SSRP1 structure specific recognition protein 1 Mapped by significant region IEA
SF3A1 splicing factor 3a, subunit 1, 120kDa Mapped by PBA pathway IDA
HNF1B HNF1 homeobox B Mapped by CNV IDA
ZNF174 zinc finger protein 174 Mapped by significant region IDA
ASRGL1 asparaginase like 1 Mapped by significant region IDA
EIF6 eukaryotic translation initiation factor 6 Mapped by LD-proxy IDA
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV IDA[9874765]
HINT3 histidine triad nucleotide binding protein 3 Mapped by significant region IDA
RPS25 ribosomal protein S25 Mapped by significant region IDA[10050887]
NUSAP1 nucleolar and spindle associated protein 1 Mapped by PBA pathway IDA
WDR74 WD repeat domain 74 Mapped by significant region IDA[12429849]
KLHL20 kelch-like family member 20 Mapped by significant region IDA
STXBP3 syntaxin binding protein 3 Mapped by CNV IDA
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 Mapped by CNV IEA
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase Mapped by CNV IDA
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) Mapped by LD-proxy IBA; ISS
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IDA[9537418]
CENPV centromere protein V Mapped by significant region IDA
RSL1D1 ribosomal L1 domain containing 1 Mapped by significant region IEA
EPB41L2 erythrocyte membrane protein band 4.1-like 2 Mapped by significant region IDA
DAXX death-domain associated protein Mapped by PBA pathway IEA
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IDA
STX5 syntaxin 5 Mapped by significant region IDA
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 Mapped by significant region IDA
GSTT2 glutathione S-transferase theta 2 Mapped by CNV IDA
CDCA7L cell division cycle associated 7-like Mapped by significant region IDA
OASL 2'-5'-oligoadenylate synthetase-like Mapped by PBA pathway IDA[9826176]
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region IDA
SNW1 SNW domain containing 1 Mapped by PBA pathway IDA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway IDA
ZBTB34 zinc finger and BTB domain containing 34 Mapped by significant region IDA
STAP1 signal transducing adaptor family member 1 Mapped by significant region IDA
CEP57 centrosomal protein 57kDa Mapped by significant region IDA
RPS10 ribosomal protein S10 Mapped by LD-proxy IDA
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[16314496]
MYO10 myosin X Mapped by significant region IDA
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Mapped by significant region IDA
FAM71B family with sequence similarity 71, member B Mapped by significant region IDA
PGR progesterone receptor Mapped by significant region IDA
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 Mapped by significant region TAS[7639753]
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 Mapped by PBA pathway IDA
BCL9L B-cell CLL/lymphoma 9-like Mapped by significant region IDA
SF1 splicing factor 1 Mapped by significant region; Mapped by PBA pathway IDA
ZNF367 zinc finger protein 367 Mapped by significant region IDA
MTG1 mitochondrial ribosome-associated GTPase 1 Mapped by CNV IDA
NOP10 NOP10 ribonucleoprotein Mapped by CNV IEA
IARS isoleucyl-tRNA synthetase Mapped by significant region IDA