ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	NFRKB
Symbol Alias	DKFZp547B2013, INO80G
Approved Name	nuclear factor related to kappaB binding protein
Name Alias	nuclear factor related to kappa B binding protein, "DNA-binding protein R kappa B", "INO80 complex subunit G"
Location	11q24-q25
Position	chr11:129733670-129765490, -
External Links	HGNC: 7802 Entrez Gene: 4798 Ensembl: ENSG00000170322 UCSC: uc001qfg.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0002020	protease binding	Molecular Function	IPI[18922472]	13
GO:0005515	protein binding	Molecular Function	IPI[19615732]	910
GO:0003677	DNA binding	Molecular Function		220
GO:0005730	nucleolus	Cellular Component		243
GO:0005634	nucleus	Cellular Component		770
GO:0006310	DNA recombination	Biological Process		14
GO:0006281	DNA repair	Biological Process		62
GO:0006954	inflammatory response	Biological Process	TAS[1777480]	51
GO:0031011	Ino80 complex	Cellular Component	IDA[18922472]	3
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS[1777480]	62

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NFRKB (count: 20)

Gene Symbol	Pathway Count	Pathway List
INO80E	7	protein binding; nucleolus; nucleus; DNA recombination; DNA repair; Ino80 complex; regulation of transcription, DNA-dependent;
SSRP1	7	protein binding; DNA binding; nucleolus; nucleus; DNA repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter;
HINFP	6	protein binding; DNA binding; nucleolus; nucleus; DNA repair; regulation of transcription, DNA-dependent;
IGHMBP2	6	protein binding; DNA binding; nucleus; DNA recombination; DNA repair; regulation of transcription, DNA-dependent;
MRE11A	6	protein binding; DNA binding; nucleolus; nucleus; DNA recombination; DNA repair;
XRCC5	6	protein binding; DNA binding; nucleolus; nucleus; DNA recombination; DNA repair;
TNFAIP3	5	protease binding; protein binding; DNA binding; nucleus; inflammatory response;
CHD1L	5	protein binding; DNA binding; nucleolus; nucleus; DNA repair;
FEN1	5	protein binding; DNA binding; nucleolus; nucleus; DNA repair;
MUS81	5	protein binding; DNA binding; nucleolus; DNA recombination; DNA repair;
NCOA6	5	protein binding; nucleolus; nucleus; DNA recombination; DNA repair;
NDNL2	5	protein binding; nucleus; DNA recombination; DNA repair; regulation of transcription, DNA-dependent;
PTTG1	5	protein binding; nucleus; DNA repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter;
RBM14	5	protein binding; nucleolus; nucleus; DNA recombination; DNA repair;
RBPJ	5	protein binding; DNA binding; nucleolus; nucleus; DNA recombination;
RPS6KA4	5	protein binding; nucleolus; nucleus; inflammatory response; regulation of transcription, DNA-dependent;
SMC1A	5	protein binding; nucleolus; nucleus; DNA recombination; DNA repair;
TAF13	5	protein binding; DNA binding; nucleolus; nucleus; transcription from RNA polymerase II promoter;
TAF4B	5	DNA binding; nucleolus; nucleus; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter;
INO80C	5	nucleolus; DNA recombination; DNA repair; Ino80 complex; regulation of transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with NFRKB (count: 0)

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Region: chr11:129733670..129765490 View in gBrowse