ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003677
Name DNA binding
Type molecular function
No. of Genes in ADHDgene  257
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 257)

Literature-origin genes (count: 21)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NFIL3 nuclear factor, interleukin 3 regulated 9q22 2(1/1/0) TAS[1620116]
ZNF423 zinc finger protein 423 16q12 1(0/0/1) IEA
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) TAS[12072434]
ZNF75A zinc finger protein 75a 16p13.11 1(0/0/1) IEA
MYT1L myelin transcription factor 1-like 2p25.3 1(0/0/1) IEA
FOXP2 forkhead box P2 7q31 1(1/0/0) IDA[16407075]
ETV5 ets variant 5 3q28 1(1/0/0) TAS[8152800]
NEUROD6 neuronal differentiation 6 7p15.1 1(0/1/0) IEA
HES1 hes family bHLH transcription factor 1 3q28-q29 1(1/0/0) TAS[7906273]
ZNF516 zinc finger protein 516 18q23 1(0/1/0) IEA
ATXN1 ataxin 1 6p23 1(0/0/1) IEA
ZNF544 zinc finger protein 544 19q13.43 1(0/0/1) IEA
ZNF805 zinc finger protein 805 19q13.43 1(0/0/1) IEA
GFI1B growth factor independent 1B transcription repressor 9q34.13 1(0/1/0) IEA
NPAS3 neuronal PAS domain protein 3 14q13.1 1(1/0/0) IEA
HOXB1 homeobox B1 17q21.32 1(0/0/1) IDA[10052460]
TMEM18 transmembrane protein 18 2p25.3 1(0/1/0) IEA
NUCB1 nucleobindin 1 19q13.33 1(0/0/1) IEA
HES6 hes family bHLH transcription factor 6 2q37.3 1(0/1/0) IEA
H2AFY H2A histone family, member Y 5q31.1 1(0/1/0) NAS[9714746]
DSCC1 DNA replication and sister chromatid cohesion 1 8q24.12 1(0/1/0) IEA

Genes from other sources Help (count: 236)

Approved Symbol Approved Name Source Evidence[PMID]
TIGD7 tigger transposable element derived 7 Mapped by LD-proxy; Mapped by significant region IEA
TIGD2 tigger transposable element derived 2 Mapped by CNV IEA
ZFP2 ZFP2 zinc finger protein Mapped by CNV IEA
ZNF618 zinc finger protein 618 Mapped by significant region IEA
CIITA class II, major histocompatibility complex, transactivator Mapped by significant region TAS[15771576]
TBX1 T-box 1 Mapped by CNV IDA[17273972]
DEAF1 DEAF1 transcription factor Mapped by Literature SNP IEA
PRM2 protamine 2 Mapped by significant region IEA
PRPF19 pre-mRNA processing factor 19 Mapped by significant region IEA
ARID3C AT rich interactive domain 3C (BRIGHT-like) Mapped by LD-proxy IEA
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa Mapped by significant region IDA[15601843]
FOXG1 forkhead box G1 Mapped by significant region TAS[7959731]
ZNF646 zinc finger protein 646 Mapped by CNV IEA
ZNF57 zinc finger protein 57 Mapped by CNV IEA
ZNF785 zinc finger protein 785 Mapped by CNV IEA
ZNF676 zinc finger protein 676 Mapped by CNV IEA
NHEJ1 nonhomologous end-joining factor 1 Mapped by significant region IEA
TAL2 T-cell acute lymphocytic leukemia 2 Mapped by significant region IEA
MYRF myelin regulatory factor Mapped by LD-proxy; Mapped by significant region IEA
ZNF648 zinc finger protein 648 Mapped by significant region IEA
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa Mapped by significant region TAS[9674425]
E2F6 E2F transcription factor 6 Mapped by significant region IEA
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV IEA
OTUD7A OTU deubiquitinase 7A Mapped by CNV; Mapped by significant region IEA
ZFPL1 zinc finger protein-like 1 Mapped by significant region NAS[9653652]
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV TAS[9874765]
E4F1 E4F transcription factor 1 Mapped by significant region TAS[10869426]
ZNF500 zinc finger protein 500 Mapped by significant region IEA
HNF1B HNF1 homeobox B Mapped by CNV IDA[1677179]
ASXL3 additional sex combs like 3 (Drosophila) Mapped by significant region IEA
ZNF629 zinc finger protein 629 Mapped by CNV IEA
FBXL19 F-box and leucine-rich repeat protein 19 Mapped by CNV IEA
TOP3A topoisomerase (DNA) III alpha Mapped by significant region TAS[8622991]
ZNF367 zinc finger protein 367 Mapped by significant region IEA
PRDM10 PR domain containing 10 Mapped by significant region IEA
ZNF131 zinc finger protein 131 Mapped by significant region IEA
TBX6 T-box 6 Mapped by CNV IEA
BANP BTG3 associated nuclear protein Mapped by significant region IEA
ZBTB3 zinc finger and BTB domain containing 3 Mapped by significant region IEA
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 Mapped by significant region IEA
OLIG3 oligodendrocyte transcription factor 3 Mapped by significant region IEA
ZNF670 zinc finger protein 670 Mapped by CNV IEA
ZNF689 zinc finger protein 689 Mapped by CNV IEA
OVOL1 ovo-like zinc finger 1 Mapped by significant region IEA
DNASE1L2 deoxyribonuclease I-like 2 Mapped by significant region TAS[9205125]
SSRP1 structure specific recognition protein 1 Mapped by significant region IEA
PGR progesterone receptor Mapped by significant region TAS[3551956]
ZNF213 zinc finger protein 213 Mapped by significant region IEA
ERCC6L2 excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2 Mapped by significant region IEA
ZFP1 ZFP1 zinc finger protein Mapped by significant region IEA
FOXF1 forkhead box F1 Mapped by significant region IDA[9769171]
ZSCAN29 zinc finger and SCAN domain containing 29 Mapped by LD-proxy IEA
PKNOX2 PBX/knotted 1 homeobox 2 Mapped by significant region IDA[12412021]
BARX2 BARX homeobox 2 Mapped by significant region IDA[10854790]
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) Mapped by significant region TAS[8670811]
ZNF669 zinc finger protein 669 Mapped by CNV IEA
TNP1 transition protein 1 (during histone to protamine replacement) Mapped by significant region IMP[12743712]
PNN pinin, desmosome associated protein Mapped by LD-proxy IEA
AKNA AT-hook transcription factor Mapped by significant region IEA
RMI2 RecQ mediated genome instability 2 Mapped by significant region IEA
PHF5A PHD finger protein 5A Mapped by PBA pathway IEA
ZNF736 zinc finger protein 736 Mapped by CNV IEA
ZBTB34 zinc finger and BTB domain containing 34 Mapped by significant region IEA
SP4 Sp4 transcription factor Mapped by significant region IEA
TRDMT1 tRNA aspartic acid methyltransferase 1 Mapped by CNV IEA
ZNF624 zinc finger protein 624 Mapped by significant region IEA
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IDA[12802276]; NAS[9294197]
CENPBD1 CENPB DNA-binding domains containing 1 Mapped by significant region IEA
TADA2A transcriptional adaptor 2A Mapped by CNV IEA
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) Mapped by significant region IEA
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region TAS[8798680]
ZFP37 ZFP37 zinc finger protein Mapped by significant region IEA
ZNF215 zinc finger protein 215 Mapped by CNV IEA
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) Mapped by Literature SNP IEA
ZNF521 zinc finger protein 521 Mapped by significant region IEA
MCM9 minichromosome maintenance complex component 9 Mapped by significant region IEA
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa Mapped by significant region IEA
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) Mapped by significant region IEA
ZNF484 zinc finger protein 484 Mapped by significant region IEA
ZNF70 zinc finger protein 70 Mapped by CNV IEA
ZNF729 zinc finger protein 729 Mapped by CNV IEA
RCOR2 REST corepressor 2 Mapped by significant region IEA
ZBTB20 zinc finger and BTB domain containing 20 Mapped by LD-proxy IEA
OASL 2'-5'-oligoadenylate synthetase-like Mapped by PBA pathway IDA[9826176]
PRM3 protamine 3 Mapped by significant region IEA
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region IEA
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa Mapped by CNV IEA
HMGB4 high mobility group box 4 Mapped by LD-proxy IEA
ZSCAN30 zinc finger and SCAN domain containing 30 Mapped by significant region IEA
ZNF532 zinc finger protein 532 Mapped by significant region IEA
ZNF664 zinc finger protein 664 Mapped by CNV IEA
HINFP histone H4 transcription factor Mapped by significant region IDA[18850719]
SNAI3 snail family zinc finger 3 Mapped by significant region IEA
ZNF883 zinc finger protein 883 Mapped by significant region IEA
RC3H2 ring finger and CCCH-type domains 2 Mapped by significant region IDA[10938276]
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region NAS[1537839]
ZNF879 zinc finger protein 879 Mapped by CNV IEA
FOXL1 forkhead box L1 Mapped by significant region IDA[7957066]
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1 Mapped by significant region IEA
ZNF74 zinc finger protein 74 Mapped by CNV IEA
SPIN1 spindlin 1 Mapped by significant region IEA
PAIP1 poly(A) binding protein interacting protein 1 Mapped by significant region IEA
ZBTB44 zinc finger and BTB domain containing 44 Mapped by significant region IEA
TIGD3 tigger transposable element derived 3 Mapped by significant region IEA
ZNF24 zinc finger protein 24 Mapped by significant region TAS[2288909]
ZNF124 zinc finger protein 124 Mapped by CNV IEA
POLA2 polymerase (DNA directed), alpha 2, accessory subunit Mapped by significant region IEA
POU2AF1 POU class 2 associating factor 1 Mapped by significant region IEA
RABGAP1 RAB GTPase activating protein 1 Mapped by significant region IEA
CENPW centromere protein W Mapped by significant region IEA
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 Mapped by significant region IDA[10581025]
STRBP spermatid perinuclear RNA binding protein Mapped by significant region IEA
FUS fused in sarcoma Mapped by CNV IEA
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Mapped by CNV; Mapped by significant region IEA
NCBP1 nuclear cap binding protein subunit 1, 80kDa Mapped by significant region IEA
SOX8 SRY (sex determining region Y)-box 8 Mapped by significant region NAS[10684944]
ZNF354B zinc finger protein 354B Mapped by CNV IEA
ZFPM1 zinc finger protein, FOG family member 1 Mapped by significant region IEA
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region IDA[19158098]
ZNF397 zinc finger protein 397 Mapped by significant region IEA
HOXA13 homeobox A13 Mapped by significant region TAS[9020844]
ZNF189 zinc finger protein 189 Mapped by significant region IEA
CENPC centromere protein C Mapped by significant region IEA
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region IDA[15790808]
TCF25 transcription factor 25 (basic helix-loop-helix) Mapped by significant region IEA
CREBZF CREB/ATF bZIP transcription factor Mapped by significant region NAS[10871379]
NDN necdin, melanoma antigen (MAGE) family member Mapped by CNV; Mapped by significant region IEA
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region ISS
TNP2 transition protein 2 (during histone to protamine replacement) Mapped by significant region IEA
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) Mapped by significant region IEA
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region IDA[11714725]
ZNF768 zinc finger protein 768 Mapped by CNV IEA
NPAS2 neuronal PAS domain protein 2 Mapped by CNV IPI[9576906]
ZNF764 zinc finger protein 764 Mapped by CNV IEA
TBPL1 TBP-like 1 Mapped by significant region IEA
MAP1S microtubule-associated protein 1S Mapped by PBA pathway IDA[15907802]
IKZF1 IKAROS family zinc finger 1 (Ikaros) Mapped by LD-proxy TAS[8543809]
ZBTB37 zinc finger and BTB domain containing 37 Mapped by significant region IEA
ZNF462 zinc finger protein 462 Mapped by significant region IEA
ZNF264 zinc finger protein 264 Mapped by LD-proxy IEA
FEN1 flap structure-specific endonuclease 1 Mapped by Literature SNP; Mapped by significant region IMP[11986308]
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Mapped by significant region IEA
ZNF469 zinc finger protein 469 Mapped by significant region IEA
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa Mapped by significant region IEA
GSC2 goosecoid homeobox 2 Mapped by CNV TAS[9441739]
MYB v-myb avian myeloblastosis viral oncogene homolog Mapped by significant region IEA
ZNF705E zinc finger protein 705E Mapped by significant region IEA
ZNF48 zinc finger protein 48 Mapped by CNV IEA
ZBTB9 zinc finger and BTB domain containing 9 Mapped by LD-proxy IEA
ZNF257 zinc finger protein 257 Mapped by CNV NAS
PRM1 protamine 1 Mapped by significant region IEA
FLI1 Fli-1 proto-oncogene, ETS transcription factor Mapped by significant region TAS[1522903]
PALB2 partner and localizer of BRCA2 Mapped by significant region IDA
ZNF597 zinc finger protein 597 Mapped by significant region IEA
ZNF778 zinc finger protein 778 Mapped by significant region IEA
NR6A1 nuclear receptor subfamily 6, group A, member 1 Mapped by significant region ISS
KLF13 Kruppel-like factor 13 Mapped by CNV; Mapped by significant region IEA
ZFR zinc finger RNA binding protein Mapped by significant region IEA
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) Mapped by significant region IDA[9931457]
ZNF77 zinc finger protein 77 Mapped by CNV IEA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
TOP3B topoisomerase (DNA) III beta Mapped by Literature SNP TAS[9786843]
UBN1 ubinuclein 1 Mapped by significant region IEA
ZNF202 zinc finger protein 202 Mapped by significant region IEA
ZNF263 zinc finger protein 263 Mapped by LD-proxy; Mapped by significant region IEA
ESRRA estrogen-related receptor alpha Mapped by significant region TAS[9286700]
PBRM1 polybromo 1 Mapped by LD-proxy IEA
CDT1 chromatin licensing and DNA replication factor 1 Mapped by significant region ISS
ZNF510 zinc finger protein 510 Mapped by significant region IEA
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway TAS[10871404]
ZBTB22 zinc finger and BTB domain containing 22 Mapped by LD-proxy IEA
FLYWCH1 FLYWCH-type zinc finger 1 Mapped by significant region IEA
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region IEA
ZNF782 zinc finger protein 782 Mapped by significant region IEA
ZNF287 zinc finger protein 287 Mapped by significant region IEA
ZNF354C zinc finger protein 354C Mapped by CNV IEA
TBX10 T-box 10 Mapped by significant region IEA
THAP7 THAP domain containing 7 Mapped by CNV IEA
CARHSP1 calcium regulated heat stable protein 1, 24kDa Mapped by significant region IEA
HOXA5 homeobox A5 Mapped by significant region IDA[8657138]
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IDA[15790681]
ZNF79 zinc finger protein 79 Mapped by significant region IEA
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IEA
EME2 essential meiotic structure-specific endonuclease subunit 2 Mapped by significant region IEA
CRAMP1L Crm, cramped-like (Drosophila) Mapped by significant region IEA
RREB1 ras responsive element binding protein 1 Mapped by CNV IEA
MUS81 MUS81 structure-specific endonuclease subunit Mapped by significant region IEA
APLP2 amyloid beta (A4) precursor-like protein 2 Mapped by significant region NAS[7702756]
THAP6 THAP domain containing 6 Mapped by CNV IEA
NRF1 nuclear respiratory factor 1 Mapped by LD-proxy IEA
HBP1 HMG-box transcription factor 1 Mapped by CNV IEA
ZNF679 zinc finger protein 679 Mapped by CNV IEA
BCLAF1 BCL2-associated transcription factor 1 Mapped by significant region IDA[10330179]
NUSAP1 nucleolar and spindle associated protein 1 Mapped by PBA pathway IEA
PC pyruvate carboxylase Mapped by significant region IEA
KIF22 kinesin family member 22 Mapped by CNV IEA
ZNF142 zinc finger protein 142 Mapped by significant region IEA
ZNF276 zinc finger protein 276 Mapped by significant region IEA
ZBTB43 zinc finger and BTB domain containing 43 Mapped by significant region IEA
SRCAP Snf2-related CREBBP activator protein Mapped by CNV IEA
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region ISS
ZNF483 zinc finger protein 483 Mapped by significant region IEA
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Mapped by significant region IEA
ELP2 elongator acetyltransferase complex subunit 2 Mapped by significant region IDA[11714725]
ZNF396 zinc finger protein 396 Mapped by significant region IEA
ZNF771 zinc finger protein 771 Mapped by CNV IEA
ZNF286B zinc finger protein 286B Mapped by significant region IEA
NCOR2 nuclear receptor corepressor 2 Mapped by CNV IEA
AHRR aryl-hydrocarbon receptor repressor Mapped by significant region IEA
FAN1 FANCD2/FANCI-associated nuclease 1 Mapped by CNV; Mapped by significant region IEA
EBF1 early B-cell factor 1 Mapped by significant region IEA
ZBTB6 zinc finger and BTB domain containing 6 Mapped by significant region IEA
GTF3A general transcription factor IIIA Mapped by LD-proxy IEA
NR5A1 nuclear receptor subfamily 5, group A, member 1 Mapped by significant region IDA[10567391]
GRHL1 grainyhead-like 1 (Drosophila) Mapped by significant region IEA
ZBTB26 zinc finger and BTB domain containing 26 Mapped by significant region IEA
ZSCAN32 zinc finger and SCAN domain containing 32 Mapped by significant region IEA
H2AFX H2A histone family, member X Mapped by significant region NAS[2587254]
FOXE1 forkhead box E1 (thyroid transcription factor 2) Mapped by significant region IDA[9697705]
ZNF511 zinc finger protein 511 Mapped by Literature SNP; Mapped by CNV IEA
PAPD7 PAP associated domain containing 7 Mapped by significant region IEA
IRF7 interferon regulatory factor 7 Mapped by LD-proxy IMP[12374802]
SETBP1 SET binding protein 1 Mapped by significant region IEA
POLR1A polymerase (RNA) I polypeptide A, 194kDa Mapped by CNV IEA
SCYL1 SCY1-like 1 (S. cerevisiae) Mapped by significant region IEA
ZNF205 zinc finger protein 205 Mapped by significant region NAS
ZNF454 zinc finger protein 454 Mapped by CNV IEA
ZNF214 zinc finger protein 214 Mapped by CNV NAS
BANF1 barrier to autointegration factor 1 Mapped by significant region IEA
ZNF169 zinc finger protein 169 Mapped by significant region IEA
JRKL jerky homolog-like (mouse) Mapped by significant region IEA
SSH3 slingshot protein phosphatase 3 Mapped by significant region IEA
NPAS4 neuronal PAS domain protein 4 Mapped by significant region IEA
FMN1 formin 1 Mapped by CNV; Mapped by significant region IEA
ZNF668 zinc finger protein 668 Mapped by CNV IEA
ZNF688 zinc finger protein 688 Mapped by CNV IEA