ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SP4
Symbol Alias	SPR-1, HF1B, MGC130008, MGC130009
Approved Name	Sp4 transcription factor
Location	7p15
Position	chr7:21467652-21554440, +
External Links	HGNC: 11209 Entrez Gene: 6671 Ensembl: ENSG00000105866 UCSC: uc003sva.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 7)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0003677	DNA binding	Molecular Function		220
GO:0005634	nucleus	Cellular Component		770
GO:0003713	transcription coactivator activity	Molecular Function	TAS[7559627]	52
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[12560508]	42
GO:0008270	zinc ion binding	Molecular Function		323

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SP4 (count: 23)

Gene Symbol	Pathway Count	Pathway List
HINFP	6	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription coactivator activity; transcription, DNA-dependent; zinc ion binding;
ZNF367	6	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; zinc ion binding;
ATF6	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription coactivator activity; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter;
IKZF1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
MYT1L	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
SREBF1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter;
TBX1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter;
TBX10	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter;
ZFP37	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF169	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF189	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF215	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF24	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF263	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF287	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF396	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF397	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF483	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF70	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZNF75CP	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZSCAN29	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
ZSCAN30	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription, DNA-dependent; zinc ion binding;
SRCAP	5	DNA binding; nucleus; transcription coactivator activity; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter;

Genes shared at least 2 KEGG pathways with SP4 (count: 0)

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Region: chr7:21467652..21554440 View in gBrowse