ADHDgene Database
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  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006351
Name transcription, DNA-dependent
Type Biological Process
No. of Genes in ADHDgene  247
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 247)

Literature-origin genes (count: 20)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HES6 hairy and enhancer of split 6 (Drosophila) 2q37.3 1(0/1/0)
ZNF805 zinc finger protein 805 19q13.43 1(0/0/1)
MYT1L myelin transcription factor 1-like 2p25.3 1(0/0/1)
HOXB1 homeobox B1 17q21.32 1(0/0/1)
ZNF75A zinc finger protein 75a 16p13.11 1(0/0/1)
NEUROD6 neurogenic differentiation 6 7p15.1 1(0/1/0)
ZNF544 zinc finger protein 544 19q13.43 1(0/0/1)
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17 1(0/1/0)
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 2(0/2/0) IDA[17184956]
ZNF423 zinc finger protein 423 16q12 1(0/0/1)
TFEB transcription factor EB 6p21 1(0/0/1)
DMRT2 doublesex and mab-3 related transcription factor 2 9p24.3 1(0/0/1)
IL16 interleukin 16 (lymphocyte chemoattractant factor) 15q26.3 1(0/0/1)
NPAS3 neuronal PAS domain protein 3 14q12-q13 1(1/0/0)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 2(2/0/0)
PER2 period homolog 2 (Drosophila) 2q37.3 1(1/0/0)
PER1 period homolog 1 (Drosophila) 17p13.1 1(0/1/0)
ATXN1 ataxin 1 6p23 1(0/0/1)
KANK2 KN motif and ankyrin repeat domains 2 19p13.2 1(0/1/0)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2p16.1 1(0/0/1)

Genes from other sources Help (count: 227)

Approved Symbol Approved Name Source Evidence[PMID]
ZNF764 zinc finger protein 764 Mapped by CNV
PRDM10 PR domain containing 10 Mapped by significant region
SRCAP Snf2-related CREBBP activator protein Mapped by CNV
ZNF75CP zinc finger protein 75C, pseudogene Mapped by significant region
HOXA3 homeobox A3 Mapped by significant region
TXN thioredoxin Mapped by significant region
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway NAS[11071939]
CNOT6 CCR4-NOT transcription complex, subunit 6 Mapped by CNV
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV
BARX2 BARX homeobox 2 Mapped by significant region
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like Mapped by significant region
LMX1B LIM homeobox transcription factor 1, beta Mapped by significant region
ZNF77 zinc finger protein 77 Mapped by CNV
PHF1 PHD finger protein 1 Mapped by LD-proxy
PHF19 PHD finger protein 19 Mapped by significant region
BARX1 BARX homeobox 1 Mapped by significant region
HOXA2 homeobox A2 Mapped by significant region
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region
PHF2 PHD finger protein 2 Mapped by significant region
ZNF782 zinc finger protein 782 Mapped by significant region
FLII flightless I homolog (Drosophila) Mapped by significant region
ZNF778 zinc finger protein 778 Mapped by significant region
ZNF771 zinc finger protein 771 Mapped by CNV
PHF3 PHD finger protein 3 Mapped by significant region
C11orf30 chromosome 11 open reading frame 30 Mapped by significant region
HOXA5 homeobox A5 Mapped by significant region
TCF25 transcription factor 25 (basic helix-loop-helix) Mapped by significant region
TRIM22 tripartite motif containing 22 Mapped by CNV
BATF2 basic leucine zipper transcription factor, ATF-like 2 Mapped by significant region
PHF5A PHD finger protein 5A Mapped by PBA pathway
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region
ZNF79 zinc finger protein 79 Mapped by significant region
ZNF785 zinc finger protein 785 Mapped by CNV
HOXA4 homeobox A4 Mapped by significant region
FLI1 Friend leukemia virus integration 1 Mapped by significant region
ZNF669 zinc finger protein 669 Mapped by CNV
RAX retina and anterior neural fold homeobox Mapped by LD-proxy; Mapped by significant region
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway
E2F5 E2F transcription factor 5, p130-binding Mapped by CNV
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) Mapped by significant region
ZBTB44 zinc finger and BTB domain containing 44 Mapped by significant region
BSX brain-specific homeobox Mapped by significant region
ZBTB6 zinc finger and BTB domain containing 6 Mapped by significant region
HOXA7 homeobox A7 Mapped by significant region
NRIP1 nuclear receptor interacting protein 1 Mapped by PBA pathway
ZNF664 zinc finger protein 664 Mapped by CNV
CREBZF CREB/ATF bZIP transcription factor Mapped by significant region IDA[10871379]
ZNF668 zinc finger protein 668 Mapped by CNV
ZBTB9 zinc finger and BTB domain containing 9 Mapped by LD-proxy
HOXA6 homeobox A6 Mapped by significant region
E2F6 E2F transcription factor 6 Mapped by significant region
ZNF688 zinc finger protein 688 Mapped by CNV
TERF2IP telomeric repeat binding factor 2, interacting protein Mapped by significant region
ZNF670 zinc finger protein 670 Mapped by CNV
PHOX2A paired-like homeobox 2a Mapped by significant region
ZNF676 zinc finger protein 676 Mapped by CNV
DPF2 D4, zinc and double PHD fingers family 2 Mapped by significant region
ZNF70 zinc finger protein 70 Mapped by CNV
BRMS1 breast cancer metastasis suppressor 1 Mapped by significant region
ZBTB22 zinc finger and BTB domain containing 22 Mapped by LD-proxy
ZNF705E zinc finger protein 705E Mapped by significant region
CHMP1A chromatin modifying protein 1A Mapped by significant region
EBF1 early B-cell factor 1 Mapped by significant region
ZNF689 zinc finger protein 689 Mapped by CNV
ZBTB26 zinc finger and BTB domain containing 26 Mapped by significant region
ZBTB3 zinc finger and BTB domain containing 3 Mapped by significant region
OLIG3 oligodendrocyte transcription factor 3 Mapped by significant region
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) Mapped by LD-proxy
PRDM1 PR domain containing 1, with ZNF domain Mapped by CNV
BANP BTG3 associated nuclear protein Mapped by significant region
WASL Wiskott-Aldrich syndrome-like Mapped by CNV
ZBTB34 zinc finger and BTB domain containing 34 Mapped by significant region
ATMIN ATM interactor Mapped by significant region
HOXA9 homeobox A9 Mapped by significant region
ZBTB37 zinc finger and BTB domain containing 37 Mapped by significant region
ZNF74 zinc finger protein 74 Mapped by CNV
ZBTB43 zinc finger and BTB domain containing 43 Mapped by significant region
L3MBTL3 l(3)mbt-like 3 (Drosophila) Mapped by CNV; Mapped by significant region
ZNF510 zinc finger protein 510 Mapped by significant region
AKNA AT-hook transcription factor Mapped by significant region
ZNF521 zinc finger protein 521 Mapped by significant region
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV
SUB1 SUB1 homolog (S. cerevisiae) Mapped by significant region
ZNF511 zinc finger protein 511 Mapped by CNV; Mapped by LD-proxy; Mapped by literature SNP
ASXL3 additional sex combs like 3 (Drosophila) Mapped by significant region
HOXB3 homeobox B3 Mapped by LD-proxy
PCGF3 polycomb group ring finger 3 Mapped by LD-proxy
ZNF532 zinc finger protein 532 Mapped by significant region
HIRA HIR histone cell cycle regulation defective homolog A (S. cerevisiae) Mapped by CNV
IRX3 iroquois homeobox 3 Mapped by CNV
TAL2 T-cell acute lymphocytic leukemia 2 Mapped by significant region
ZNF618 zinc finger protein 618 Mapped by significant region
ZNF57 zinc finger protein 57 Mapped by CNV
LHX6 LIM homeobox 6 Mapped by significant region
KCTD1 potassium channel tetramerisation domain containing 1 Mapped by significant region
NEUROD2 neurogenic differentiation 2 Mapped by LD-proxy
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region
MEN1 multiple endocrine neoplasia I Mapped by significant region
UBB ubiquitin B Mapped by significant region
ZNF629 zinc finger protein 629 Mapped by CNV
NUP62 nucleoporin 62kDa Mapped by PBA pathway IDA[10373430]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway IDA[14701856]
ZNF624 zinc finger protein 624 Mapped by significant region
ZNF646 zinc finger protein 646 Mapped by CNV
ASF1A ASF1 anti-silencing function 1 homolog A (S. cerevisiae) Mapped by significant region
SAP18 Sin3A-associated protein, 18kDa Mapped by significant region
HINFP histone H4 transcription factor Mapped by significant region
MPHOSPH8 M-phase phosphoprotein 8 Mapped by significant region
PBX3 pre-B-cell leukemia homeobox 3 Mapped by significant region
PTPN14 protein tyrosine phosphatase, non-receptor type 14 Mapped by literature SNP
ZNF648 zinc finger protein 648 Mapped by significant region
ZNF367 zinc finger protein 367 Mapped by significant region
ERN2 endoplasmic reticulum to nucleus signaling 2 Mapped by significant region
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy
DAXX death-domain associated protein Mapped by LD-proxy; Mapped by PBA pathway
RFX6 regulatory factor X, 6 Mapped by significant region
SCAI suppressor of cancer cell invasion Mapped by significant region
ZNF396 zinc finger protein 396 Mapped by significant region
SETD1A SET domain containing 1A Mapped by CNV
ZNF397 zinc finger protein 397 Mapped by significant region
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa Mapped by significant region NAS[7801123]
VGLL2 vestigial like 2 (Drosophila) Mapped by significant region
ZNF454 zinc finger protein 454 Mapped by CNV
EED embryonic ectoderm development Mapped by significant region
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) Mapped by LD-proxy; Mapped by literature SNP
ZNF462 zinc finger protein 462 Mapped by significant region
ZNF469 zinc finger protein 469 Mapped by significant region
ZNF48 zinc finger protein 48 Mapped by CNV
KDM4D lysine (K)-specific demethylase 4D Mapped by significant region
ATF6 activating transcription factor 6 Mapped by CNV
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa Mapped by significant region
POU2F3 POU class 2 homeobox 3 Mapped by significant region
ZNF483 zinc finger protein 483 Mapped by significant region
ZNF484 zinc finger protein 484 Mapped by significant region
KDM2A lysine (K)-specific demethylase 2A Mapped by significant region
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region
ZNF264 zinc finger protein 264 Mapped by LD-proxy
CTNND2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) Mapped by CNV
UTF1 undifferentiated embryonic cell transcription factor 1 Mapped by CNV
ZNF263 zinc finger protein 263 Mapped by LD-proxy
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway
ACAD8 acyl-CoA dehydrogenase family, member 8 Mapped by CNV; Mapped by significant region
ZNF257 zinc finger protein 257 Mapped by CNV
ETS1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) Mapped by significant region
ZNF24 zinc finger protein 24 Mapped by significant region
CTNND1 catenin (cadherin-associated protein), delta 1 Mapped by significant region
SF1 splicing factor 1 Mapped by PBA pathway; Mapped by significant region
ZNF354C zinc finger protein 354C Mapped by CNV
ZNF354B zinc finger protein 354B Mapped by CNV
TSHZ2 teashirt zinc finger homeobox 2 Mapped by LD-proxy; Mapped by literature SNP
ZNF287 zinc finger protein 287 Mapped by significant region
BIRC2 baculoviral IAP repeat containing 2 Mapped by significant region
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) Mapped by CNV
ZNF286B zinc finger protein 286B Mapped by significant region
ZNF276 zinc finger protein 276 Mapped by significant region
RNF2 ring finger protein 2 Mapped by significant region
ZNF142 zinc finger protein 142 Mapped by significant region
NPAT nuclear protein, ataxia-telangiectasia locus Mapped by CNV; Mapped by significant region
HBP1 HMG-box transcription factor 1 Mapped by CNV
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) Mapped by significant region
TBX1 T-box 1 Mapped by CNV
ZMYM2 zinc finger, MYM-type 2 Mapped by significant region
UBC ubiquitin C Mapped by CNV
LHX2 LIM homeobox 2 Mapped by significant region
EYA4 eyes absent homolog 4 (Drosophila) Mapped by significant region
NPAS2 neuronal PAS domain protein 2 Mapped by CNV
ZNF215 zinc finger protein 215 Mapped by CNV
ZNF214 zinc finger protein 214 Mapped by CNV
HABP4 hyaluronan binding protein 4 Mapped by significant region
PRKCB protein kinase C, beta Mapped by significant region
GRHL1 grainyhead-like 1 (Drosophila) Mapped by significant region
PSPC1 paraspeckle component 1 Mapped by significant region
NPAS4 neuronal PAS domain protein 4 Mapped by significant region
SS18 synovial sarcoma translocation, chromosome 18 Mapped by significant region
ZNF169 zinc finger protein 169 Mapped by significant region
ZNF189 zinc finger protein 189 Mapped by significant region
RCOR2 REST corepressor 2 Mapped by significant region
PELP1 proline, glutamate and leucine rich protein 1 Mapped by LD-proxy
TBX10 T-box 10 Mapped by significant region
INO80E INO80 complex subunit E Mapped by CNV
INO80C INO80 complex subunit C Mapped by significant region
NCOR2 nuclear receptor corepressor 2 Mapped by CNV
THAP7 THAP domain containing 7 Mapped by CNV
TMEM18 transmembrane protein 18 Mapped by CNV
IKZF1 IKAROS family zinc finger 1 (Ikaros) Mapped by LD-proxy
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 Mapped by significant region
BCL9L B-cell CLL/lymphoma 9-like Mapped by significant region
MURC muscle-related coiled-coil protein Mapped by significant region
LPIN1 lipin 1 Mapped by significant region
HOXA1 homeobox A1 Mapped by significant region
ZSCAN30 zinc finger and SCAN domain containing 30 Mapped by significant region
BCLAF1 BCL2-associated transcription factor 1 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
CBX3 chromobox homolog 3 Mapped by CNV; Mapped by significant region
ARID3C AT rich interactive domain 3C (BRIGHT-like) Mapped by LD-proxy
NDN necdin homolog (mouse) Mapped by CNV; Mapped by significant region
ZSCAN29 zinc finger and SCAN domain containing 29 Mapped by LD-proxy
HOXA10 homeobox A10 Mapped by significant region
NCOA7 nuclear receptor coactivator 7 Mapped by significant region
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region
CDCA7L cell division cycle associated 7-like Mapped by significant region
NSD1 nuclear receptor binding SET domain protein 1 Mapped by PBA pathway
THRSP thyroid hormone responsive Mapped by significant region
USP22 ubiquitin specific peptidase 22 Mapped by significant region
CCDC85B coiled-coil domain containing 85B Mapped by significant region
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) Mapped by CNV
JAZF1 JAZF zinc finger 1 Mapped by significant region
JMJD1C jumonji domain containing 1C Mapped by PBA pathway
HOXA11 homeobox A11 Mapped by significant region
SCYL1 SCY1-like 1 (S. cerevisiae) Mapped by significant region
HSPA8 heat shock 70kDa protein 8 Mapped by significant region
MYB v-myb myeloblastosis viral oncogene homolog (avian) Mapped by significant region
ZFP2 zinc finger protein 2 homolog (mouse) Mapped by CNV
ONECUT2 one cut homeobox 2 Mapped by significant region
NCOR1 nuclear receptor corepressor 1 Mapped by significant region
SOX30 SRY (sex determining region Y)-box 30 Mapped by significant region
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) Mapped by significant region
ZFP37 zinc finger protein 37 homolog (mouse) Mapped by significant region
ZFP62 zinc finger protein 62 homolog (mouse) Mapped by CNV
HOXA13 homeobox A13 Mapped by significant region
SNAI3 snail homolog 3 (Drosophila) Mapped by significant region
ZNF879 zinc finger protein 879 Mapped by CNV
LPXN leupaxin Mapped by significant region
ZNF883 zinc finger protein 883 Mapped by significant region
SP4 Sp4 transcription factor Mapped by significant region
ZFP1 zinc finger protein 1 homolog (mouse) Mapped by significant region

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Last update: Feb 26, 2014