ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ZNF189
Approved Name	zinc finger protein 189
Location	9q22-q31
Position	chr9:104161155-104172942, 1
External Links	HGNC: 12980 Entrez Gene: 7743 Ensembl: ENSG00000136870 UCSC: uc004bbh.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0008270	zinc ion binding	molecular function	IEA	367
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological process	TAS[9653648]	90
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	TAS[9653648]	148
GO:0005634	nucleus	cellular component	IEA	877
GO:0003677	DNA binding	molecular function	IEA	257

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ZNF189 (count: 28)

Gene Symbol	Pathway Count	Pathway List
IKZF1	6	transcription, DNA-dependent; zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF500	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF174	5	transcription, DNA-dependent; zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus;
ZNF396	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
PRDM1	5	transcription, DNA-dependent; zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus;
ZNF287	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZSCAN30	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF483	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
SP4	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
DRAP1	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
SREBF1	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF397	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF24	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF263	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZFP37	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF131	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF367	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
MYT1L	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
HINFP	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF213	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF169	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZSCAN29	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF215	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
TCF25	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
E4F1	5	transcription, DNA-dependent; zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; DNA binding;
ZNF70	5	transcription, DNA-dependent; zinc ion binding; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;
ZNF205	5	transcription, DNA-dependent; zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; DNA binding;
ZNF202	5	zinc ion binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; DNA binding;

Genes shared at least 2 KEGG pathways with ZNF189 (count: 0)

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Region: chr9:104161155..104172942 View in gBrowse