ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MYT1L
Symbol Alias	KIAA1106, NZF1
Approved Name	myelin transcription factor 1-like
Name Alias	neural zinc finger transcription factor 1
Location	2p25.3
Position	chr2:1792885-2335045, -
External Links	HGNC: 7623 Entrez Gene: 23040 Ensembl: ENSG00000186487 UCSC: uc002qxd.2
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lesch KP, 2008	Trend associated SNP was mapped in this gene.	Trend

Gene related SNPs (count: 17)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs2241685	Chr2:1925993(Fwd)	intron_variant	1(0/0/1)

LD-proxies (count: 16)

rs_ID	Location	Functional Annotation
rs1432539	Chr2:1919847(Fwd)	intron_variant; upstream_gene_variant
rs7588882	Chr2:1931058(Fwd)	intron_variant
rs4557005	Chr2:1919696(Fwd)	intron_variant; upstream_gene_variant
rs12472983	Chr2:1881964(Fwd)	intron_variant
rs3934844	Chr2:1878679(Fwd)	intron_variant
rs11127299	Chr2:1961787(Fwd)	intron_variant
rs11695699	Chr2:1954444(Fwd)	intron_variant
rs919718	Chr2:1952576(Fwd)	intron_variant
rs6548052	Chr2:1951082(Fwd)	intron_variant
rs6722043	Chr2:1950521(Fwd)	intron_variant
rs3748989	Chr2:1946968(Fwd)	synonymous_variant
rs7569044	Chr2:1951254(Fwd)	intron_variant
rs2195903	Chr2:1907446(Fwd)	intron_variant; nc_transcript_variant; upstream_gene_variant
rs13016585	Chr2:1934252(Fwd)	intron_variant
rs11127305	Chr2:1902562(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant
rs11127306	Chr2:1887049(Fwd)	downstream_gene_variant; intron_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 7)

ID	Name	Type	No. of Genes in ADHDgene
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	132
GO:0003677	DNA binding	Molecular Function	220
GO:0007399	nervous system development	Biological Process	54
GO:0008270	zinc ion binding	Molecular Function	323
GO:0005634	nucleus	Cellular Component	770
GO:0006351	transcription, DNA-dependent	Biological Process	247
GO:0030154	cell differentiation	Biological Process	51

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MYT1L (count: 21)

Gene Symbol	Pathway Count	Pathway List
ZNF423	6	DNA binding; nervous system development; zinc ion binding; nucleus; transcription, DNA-dependent; cell differentiation;
HES6	5	sequence-specific DNA binding transcription factor activity; DNA binding; nervous system development; transcription, DNA-dependent; cell differentiation;
HINFP	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
IKZF1	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
SP4	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZFP37	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF169	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF189	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF215	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF24	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF263	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF287	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF367	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF396	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF397	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF483	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF70	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF75CP	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZSCAN29	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZSCAN30	5	sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent;
ZNF521	5	DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; cell differentiation;

Genes shared at least 2 KEGG pathways with MYT1L (count: 0)

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Region: chr2:1792885..2335045 View in gBrowse