ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003713
Name transcription coactivator activity
Type molecular function
No. of Genes in ADHDgene  58
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 58)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA[7555706]
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) TAS[8419915]
TRIM32 tripartite motif containing 32 9q33.1 1(0/0/1) TAS[7778269]
MED27 mediator complex subunit 27 9q34.13 1(0/1/0) IDA[10882111]
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 1(0/0/1) IDA[11564863]

Genes from other sources Help (count: 53)

Approved Symbol Approved Name Source Evidence[PMID]
NR5A1 nuclear receptor subfamily 5, group A, member 1 Mapped by significant region TAS[8205615]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway NAS[8804307]
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa Mapped by significant region IDA[11564863]
E4F1 E4F transcription factor 1 Mapped by significant region TAS[9121437]
NPAT nuclear protein, ataxia-telangiectasia locus Mapped by CNV; Mapped by significant region IDA[14585971]; IMP[15988025]
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway IDA[11443112]
HINFP histone H4 transcription factor Mapped by significant region IDA[18850719]
CREBBP CREB binding protein Mapped by significant region IDA[12169688]; IDA[12929931]; IPI[8684459]
ATF6 activating transcription factor 6 Mapped by CNV TAS[10866666]
MED13 mediator complex subunit 13 Mapped by PBA pathway IDA[12037571]
MED23 mediator complex subunit 23 Mapped by significant region TAS[9989412]
MAML2 mastermind-like 2 (Drosophila) Mapped by significant region IDA[12370315]
MKL2 MKL/myocardin-like 2 Mapped by significant region IDA[14565952]
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa Mapped by CNV IDA[11564863]
MED17 mediator complex subunit 17 Mapped by significant region; Mapped by PBA pathway IDA[12037571]
MED16 mediator complex subunit 16 Mapped by PBA pathway TAS[10198638]
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[12037571]; IMP[17223341]
MED7 mediator complex subunit 7 Mapped by significant region TAS[9989412]
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway IMP[11279242]
SNW1 SNW domain containing 1 Mapped by PBA pathway IDA[14985122]
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IDA[14966270]; TAS[17360565]
SRCAP Snf2-related CREBBP activator protein Mapped by CNV TAS[10347196]
PRPF6 pre-mRNA processing factor 6 Mapped by PBA pathway IGI[16414017]
YAP1 Yes-associated protein 1 Mapped by significant region IDA[18280240]
USP22 ubiquitin specific peptidase 22 Mapped by significant region IDA[18206972]
LPIN1 lipin 1 Mapped by significant region IEA
MED12 mediator complex subunit 12 Mapped by PBA pathway IDA[12037571]
NFE2L3 nuclear factor, erythroid 2-like 3 Mapped by CNV; Mapped by significant region TAS[10037736]
NRIP1 nuclear receptor interacting protein 1 Mapped by PBA pathway IDA[11518808]; NAS[15572661]
SP4 Sp4 transcription factor Mapped by significant region TAS[7559627]
TBPL1 TBP-like 1 Mapped by significant region TAS[10220372]
RAN RAN, member RAS oncogene family Mapped by PBA pathway NAS[15572661]
HSF2 heat shock transcription factor 2 Mapped by significant region TAS[1871106]
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV IMP[16687403]; NAS[8804307]
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV IDA[11101851]
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Mapped by significant region TAS[7749981]
PHF2 PHD finger protein 2 Mapped by significant region IDA
TGFB1I1 transforming growth factor beta 1 induced transcript 1 Mapped by PBA pathway IDA[10075738]; NAS[15572661]
VGLL2 vestigial like 2 (Drosophila) Mapped by significant region IEA
AIP aryl hydrocarbon receptor interacting protein Mapped by significant region TAS[9447995]
SUB1 SUB1 homolog (S. cerevisiae) Mapped by significant region IDA[8062391]
CIITA class II, major histocompatibility complex, transactivator Mapped by significant region TAS[7749984]
UBE3A ubiquitin protein ligase E3A Mapped by CNV; Mapped by significant region IEA
RIPK3 receptor-interacting serine-threonine kinase 3 Mapped by significant region TAS[10339433]
BCL9L B-cell CLL/lymphoma 9-like Mapped by significant region NAS[19328798]
UTF1 undifferentiated embryonic cell transcription factor 1 Mapped by CNV IDA[9748258]
MED14 mediator complex subunit 14 Mapped by PBA pathway IDA[12037571]
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway IDA[12037571]
POU2AF1 POU class 2 associating factor 1 Mapped by significant region TAS[7859290]
BIRC2 baculoviral IAP repeat containing 2 Mapped by significant region IMP
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) Mapped by significant region IDA[11171123]
CD3D CD3d molecule, delta (CD3-TCR complex) Mapped by significant region IDA[2017177]
RNF20 ring finger protein 20, E3 ubiquitin protein ligase Mapped by significant region IDA[16337599]