ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PHF2
Symbol Alias	KIAA0662, JHDM1E
Approved Name	PHD finger protein 2
Name Alias	jumonji C domain-containing histone demethylase 1E
Location	9q22
Position	chr9:96338689-96441869, +
External Links	HGNC: 8920 Entrez Gene: 5253 Ensembl: ENSG00000197724 UCSC: uc004aub.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q22	chr9:90400000-102600000	3 (1/1/1)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component		243
GO:0005634	nucleus	Cellular Component	TAS[10051327]	770
GO:0006482	protein demethylation	Biological Process		3
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular Function		11
GO:0008270	zinc ion binding	Molecular Function		323
GO:0032454	histone demethylase activity (H3-K9 specific)	Molecular Function		2
GO:0032452	histone demethylase activity	Molecular Function		2
GO:0061188	negative regulation of chromatin silencing at rDNA	Biological Process		1
GO:0035064	methylated histone residue binding	Molecular Function		7
GO:0005506	iron ion binding	Molecular Function		20
GO:0005515	protein binding	Molecular Function		910
GO:0001889	liver development	Biological Process		14
GO:0003713	transcription coactivator activity	Molecular Function		52

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PHF2 (count: 10)

Gene Symbol	Pathway Count	Pathway List
HINFP	6	nucleolus; nucleus; transcription, DNA-dependent; zinc ion binding; protein binding; transcription coactivator activity;
KDM1A	6	nucleus; protein demethylation; transcription, DNA-dependent; histone demethylase activity (H3-K9 specific); histone demethylase activity; protein binding;
KAT5	5	nucleolus; nucleus; transcription, DNA-dependent; protein binding; transcription coactivator activity;
MED1	5	nucleolus; nucleus; protein binding; liver development; transcription coactivator activity;
RNF2	5	nucleolus; nucleus; transcription, DNA-dependent; zinc ion binding; protein binding;
RNF20	5	nucleolus; nucleus; zinc ion binding; protein binding; transcription coactivator activity;
RRP8	5	nucleolus; nucleus; transcription, DNA-dependent; methylated histone residue binding; protein binding;
SMARCB1	5	nucleolus; nucleus; transcription, DNA-dependent; protein binding; transcription coactivator activity;
SUB1	5	nucleolus; nucleus; transcription, DNA-dependent; protein binding; transcription coactivator activity;
BIRC2	5	nucleus; transcription, DNA-dependent; zinc ion binding; protein binding; transcription coactivator activity;

Genes shared at least 2 KEGG pathways with PHF2 (count: 0)

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Region: chr9:96338689..96441869 View in gBrowse