ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	KDM1A
Previous Symbol	AOF2, KDM1
Symbol Alias	KIAA0601, BHC110, LSD1
Approved Name	lysine (K)-specific demethylase 1A
Previous Name	amine oxidase (flavin containing) domain 2, "lysine (K)-specific demethylase 1"
Location	1p36.12
Position	chr1:23345941-23410184, +
External Links	HGNC: 29079 Entrez Gene: 23028 Ensembl: ENSG00000004487
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)

rs_ID	Location	Functional Annotation
rs7543975	Chr1:23381116(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant
rs7548692	Chr1:23354877(Fwd)	intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 50)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 50)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005634	nucleus	Cellular Component	IDA[19497860]	770
GO:0005515	protein binding	Molecular Function		910
GO:0005667	transcription factor complex	Cellular Component		51
GO:0005654	nucleoplasm	Cellular Component		183
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IMP[16079795]	42
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0007596	blood coagulation	Biological Process		83
GO:0006482	protein demethylation	Biological Process	IMP[17805299]	3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IMP[17805299]	78
GO:0001085	RNA polymerase II transcription factor binding	Molecular Function		10
GO:0000790	nuclear chromatin	Cellular Component	IDA[17277772]	11
GO:0002039	p53 binding	Molecular Function	IPI[17805299]	11
GO:0001701	in utero embryonic development	Biological Process		32
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0003682	chromatin binding	Molecular Function		48
GO:0032091	negative regulation of protein binding	Biological Process	IMP[17805299]	4
GO:0032451	demethylase activity	Molecular Function	IMP[17805299]	1
GO:0032452	histone demethylase activity	Molecular Function	IDA[19497860]	2
GO:0032453	histone demethylase activity (H3-K4 specific)	Molecular Function	IDA[15620353]	1
GO:0032454	histone demethylase activity (H3-K9 specific)	Molecular Function	IDA[16079795]	2
GO:0033169	histone H3-K9 demethylation	Biological Process	IDA[16079795]	1
GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)	Molecular Function		1
GO:0034720	histone H3-K4 demethylation	Biological Process	IDA[15620353]	1
GO:0008134	transcription factor binding	Molecular Function		38
GO:0008283	cell proliferation	Biological Process		60
GO:0010725	regulation of primitive erythrocyte differentiation	Biological Process		1
GO:0016491	oxidoreductase activity	Molecular Function	IDA[15620353]	21
GO:0019899	enzyme binding	Molecular Function	IPI[17277772]	47
GO:0021983	pituitary gland development	Biological Process		4
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	Molecular Function	IMP[16079795]	19
GO:0030851	granulocyte differentiation	Biological Process		4
GO:0050660	flavin adenine dinucleotide binding	Molecular Function	IDA[15620353]	11
GO:0046886	positive regulation of hormone biosynthetic process	Biological Process		1
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	IDA[19497860]	64
GO:0051573	negative regulation of histone H3-K9 methylation	Biological Process		1
GO:0051572	negative regulation of histone H3-K4 methylation	Biological Process		1
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	Biological Process		11
GO:0050681	androgen receptor binding	Molecular Function	IDA[16079795]	10
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	Biological Process	IDA[19497860]; IMP[17805299]	6
GO:0043426	MRF binding	Molecular Function		1
GO:0043392	negative regulation of DNA binding	Biological Process	IC[17805299]	5
GO:0043066	negative regulation of apoptotic process	Biological Process	IMP[17805299]	77
GO:0045654	positive regulation of megakaryocyte differentiation	Biological Process		1
GO:0045648	positive regulation of erythrocyte differentiation	Biological Process		3
GO:0044212	transcription regulatory region DNA binding	Molecular Function		23
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	Biological Process	IMP[17805299]	2
GO:2000648	positive regulation of stem cell proliferation	Biological Process		2
GO:0055001	muscle cell development	Biological Process		2
GO:2000179	positive regulation of neural precursor cell proliferation	Biological Process		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KDM1A (count: 113)

Gene Symbol	Pathway Count	Pathway List
GATA6	14	nucleus; protein binding; transcription factor complex; nucleoplasm; blood coagulation; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; sequence-specific DNA binding transcription factor activity; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process; transcription regulatory region DNA binding;
RELA	11	nucleus; protein binding; transcription factor complex; nucleoplasm; sequence-specific DNA binding transcription factor activity; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process; transcription regulatory region DNA binding;
HINFP	10	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; in utero embryonic development; sequence-specific DNA binding transcription factor activity; chromatin binding; enzyme binding; negative regulation of transcription, DNA-dependent; transcription regulatory region DNA binding;
HMGA1	10	nucleus; protein binding; transcription factor complex; nucleoplasm; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor binding; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; negative regulation of transcription, DNA-dependent;
MEN1	10	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding;
NCOR1	10	nucleus; protein binding; transcription factor complex; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; sequence-specific DNA binding transcription factor activity; chromatin binding; transcription regulatory region DNA binding;
ETS1	9	nucleus; protein binding; transcription factor complex; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor binding; pituitary gland development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of erythrocyte differentiation;
MED1	9	nucleus; protein binding; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process;
MTA2	9	nucleus; protein binding; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription factor binding; sequence-specific DNA binding transcription factor activity; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
YAP1	9	nucleus; protein binding; transcription factor complex; nucleoplasm; chromatin binding; cell proliferation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; transcription regulatory region DNA binding;
MYB	9	protein binding; transcription, DNA-dependent; blood coagulation; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; sequence-specific DNA binding transcription factor activity; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
DAXX	8	nucleus; protein binding; transcription, DNA-dependent; p53 binding; transcription factor binding; enzyme binding; negative regulation of transcription, DNA-dependent; androgen receptor binding;
FOXC2	8	nucleus; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; transcription regulatory region DNA binding;
GSK3B	8	nucleus; protein binding; RNA polymerase II transcription factor binding; p53 binding; negative regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process;
HNF1B	8	nucleus; protein binding; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; transcription regulatory region DNA binding;
KAT5	8	nucleus; protein binding; transcription factor complex; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; androgen receptor binding;
NCOA6	8	nucleus; protein binding; transcription factor complex; nucleoplasm; chromatin binding; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
PRKCB	8	nucleus; protein binding; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; blood coagulation; chromatin binding; ligand-dependent nuclear receptor transcription coactivator activity; androgen receptor binding;
SMARCB1	8	nucleus; protein binding; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; p53 binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity;
SMARCD3	8	nucleus; protein binding; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; nuclear chromatin; transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity;
SREBF1	8	nucleus; protein binding; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; chromatin binding; positive regulation of transcription from RNA polymerase II promoter;
TFAP2A	8	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process; transcription regulatory region DNA binding;
XRCC5	8	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; cell proliferation; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process; transcription regulatory region DNA binding;
CBFA2T3	8	protein binding; nucleoplasm; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; chromatin binding; cell proliferation; granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter;
SPI1	8	protein binding; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription factor binding; nuclear chromatin; sequence-specific DNA binding transcription factor activity; granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
ZFPM1	8	protein binding; transcription factor complex; nucleoplasm; blood coagulation; RNA polymerase II transcription factor binding; negative regulation of protein binding; transcription factor binding; granulocyte differentiation;
KLF4	8	transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription factor binding; nuclear chromatin; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; transcription regulatory region DNA binding;
DAB2	7	nucleus; protein binding; in utero embryonic development; negative regulation of protein binding; cell proliferation; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process;
FOXE1	7	nucleus; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
FOXF1	7	nucleus; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
FOXP1	7	nucleus; transcription factor complex; in utero embryonic development; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
HES1	7	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
HEY2	7	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
HIRA	7	nucleus; protein binding; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; nuclear chromatin; sequence-specific DNA binding transcription factor activity; chromatin binding;
HOXA7	7	nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
ID2	7	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of DNA binding; positive regulation of erythrocyte differentiation;
POU2F3	7	nucleus; protein binding; transcription factor complex; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
RBPJ	7	nucleus; protein binding; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
SNW1	7	nucleus; protein binding; nucleoplasm; regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
STRN3	7	nucleus; protein binding; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
E2F5	7	protein binding; transcription factor complex; nucleoplasm; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter;
VEGFA	7	protein binding; regulation of transcription from RNA polymerase II promoter; blood coagulation; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process;
ARRB1	6	nucleus; protein binding; blood coagulation; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
ATF6	6	nucleus; protein binding; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
ATXN1	6	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
FOSL1	6	nucleus; protein binding; regulation of transcription from RNA polymerase II promoter; in utero embryonic development; sequence-specific DNA binding transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity;
FOXG1	6	nucleus; protein binding; transcription factor complex; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
GFI1B	6	nucleus; protein binding; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription factor binding; cell proliferation;
HOXA9	6	nucleus; protein binding; transcription factor complex; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; enzyme binding;
ISL1	6	nucleus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; chromatin binding; pituitary gland development; positive regulation of transcription from RNA polymerase II promoter;
LPIN1	6	nucleus; transcription factor complex; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription factor binding; positive regulation of transcription from RNA polymerase II promoter;
MAPK1	6	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; blood coagulation; transcription factor binding;
MED17	6	nucleus; transcription factor complex; nucleoplasm; regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
MEIS2	6	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter;
NCOR2	6	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding;
NR5A1	6	nucleus; protein binding; nucleoplasm; chromatin binding; enzyme binding; positive regulation of transcription from RNA polymerase II promoter;
NRIP1	6	nucleus; protein binding; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; androgen receptor binding;
PHF2	6	nucleus; protein binding; transcription, DNA-dependent; protein demethylation; histone demethylase activity; histone demethylase activity (H3-K9 specific);
PLK1	6	nucleus; protein binding; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; cell proliferation; negative regulation of apoptotic process;
TBX1	6	nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; cell proliferation; positive regulation of transcription from RNA polymerase II promoter;
TFEB	6	nucleus; transcription factor complex; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
TP53BP1	6	nucleus; protein binding; nucleoplasm; p53 binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity;
TXN	6	protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; cell proliferation; enzyme binding;
BARX2	6	transcription factor complex; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; chromatin binding; positive regulation of transcription from RNA polymerase II promoter;
AATF	5	nucleus; protein binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process;
APBB1	5	nucleus; protein binding; transcription, DNA-dependent; chromatin binding; transcription factor binding;
BSX	5	nucleus; transcription factor complex; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
CBX3	5	nucleus; protein binding; transcription, DNA-dependent; enzyme binding; negative regulation of transcription, DNA-dependent;
CLOCK	5	nucleus; transcription factor complex; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
CREBZF	5	nucleus; protein binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent;
DRAP1	5	nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor binding;
EED	5	nucleus; protein binding; transcription, DNA-dependent; chromatin binding; negative regulation of transcription, DNA-dependent;
ELK3	5	nucleus; protein binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent;
FLCN	5	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter;
FOXD4	5	nucleus; transcription factor complex; sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter;
H2AFX	5	nucleus; protein binding; nucleoplasm; nuclear chromatin; enzyme binding;
HABP4	5	nucleus; protein binding; transcription, DNA-dependent; blood coagulation; negative regulation of DNA binding;
HOXA1	5	nucleus; protein binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
HOXA13	5	nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
HOXA2	5	nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
HOXA5	5	nucleus; protein binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
IKZF1	5	nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
IRF7	5	nucleus; protein binding; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
LMX1B	5	nucleus; protein binding; transcription, DNA-dependent; in utero embryonic development; sequence-specific DNA binding transcription factor activity;
MAPK3	5	nucleus; protein binding; nucleoplasm; blood coagulation; positive regulation of transcription from RNA polymerase II promoter;
MAPK7	5	nucleus; protein binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process;
MED12	5	nucleus; nucleoplasm; chromatin binding; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
MED14	5	nucleus; nucleoplasm; regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
MLL	5	nucleus; protein binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding;
NCOA7	5	nucleus; protein binding; transcription, DNA-dependent; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
NEDD4L	5	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter;
NEUROD2	5	nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity;
NIPBL	5	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; negative regulation of transcription, DNA-dependent;
NR4A2	5	nucleus; protein binding; nucleoplasm; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
NSD1	5	nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; androgen receptor binding;
PRKAA1	5	nucleus; protein binding; transcription, DNA-dependent; chromatin binding; negative regulation of apoptotic process;
PRPF6	5	nucleus; protein binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; androgen receptor binding;
RBM14	5	nucleus; protein binding; transcription factor complex; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
RCC1	5	nucleus; protein binding; nucleoplasm; nuclear chromatin; chromatin binding;
RNF2	5	nucleus; protein binding; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding;
RSF1	5	nucleus; protein binding; nucleoplasm; negative regulation of transcription, DNA-dependent; negative regulation of DNA binding;
SS18	5	nucleus; protein binding; transcription, DNA-dependent; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of transcription from RNA polymerase II promoter;
SUB1	5	nucleus; protein binding; transcription factor complex; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent;
TAF10	5	nucleus; protein binding; nucleoplasm; sequence-specific DNA binding transcription factor activity; enzyme binding;
TCF25	5	nucleus; protein binding; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity;
UTF1	5	nucleus; protein binding; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
WWOX	5	nucleus; protein binding; oxidoreductase activity; enzyme binding; positive regulation of transcription from RNA polymerase II promoter;
ZNF24	5	nucleus; protein binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent;
UBB	5	protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
UBC	5	protein binding; nucleoplasm; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
FOXP2	5	transcription factor complex; sequence-specific DNA binding transcription factor activity; chromatin binding; transcription factor binding; negative regulation of transcription, DNA-dependent;
HES6	5	transcription factor complex; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor binding;
RCOR2	5	transcription factor complex; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; chromatin binding; negative regulation of transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with KDM1A (count: 0)

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Region: chr1:23345941..23410184 View in gBrowse