ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	KDM1A
Previous Symbol	AOF2, KDM1
Symbol Alias	KIAA0601, BHC110, LSD1
Approved Name	lysine (K)-specific demethylase 1A
Previous Name	"amine oxidase (flavin containing) domain 2", "lysine (K)-specific demethylase 1"
Location	1p36.12
Position	chr1:23345941-23410182, 1
External Links	HGNC: 29079 Entrez Gene: 23028 Ensembl: ENSG00000004487 UCSC: uc001bgj.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)

rs_ID	Location	Functional Annotation
rs7543975	chr1:23381116(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant
rs7548692	chr1:23354877(Fwd)	intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 50)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 50)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044212	transcription regulatory region DNA binding	molecular function	ISS	28
GO:2000648	positive regulation of stem cell proliferation	biological process	IEA	2
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IEA	148
GO:0045654	positive regulation of megakaryocyte differentiation	biological process	IEA	1
GO:0008134	transcription factor binding	molecular function	IDA	44
GO:0045892	negative regulation of transcription, DNA-dependent	biological process	IDA[19497860]	77
GO:0032452	histone demethylase activity	molecular function	IDA[19497860]	2
GO:0032091	negative regulation of protein binding	biological process	IMP[17805299]	4
GO:0002039	p53 binding	molecular function	IPI[17805299]	15
GO:0045648	positive regulation of erythrocyte differentiation	biological process	IEA	3
GO:0000790	nuclear chromatin	cellular component	IDA[17277772]; ISS	12
GO:0034720	histone H3-K4 demethylation	biological process	IDA[15620353]	1
GO:0051573	negative regulation of histone H3-K9 methylation	biological process	IEA	1
GO:0019899	enzyme binding	molecular function	IPI[17277772]	54
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	biological process	IDA	12
GO:0032451	demethylase activity	molecular function	IMP[17805299]	1
GO:0021983	pituitary gland development	biological process	IEA	4
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	biological process	IDA[19497860]; IMP[17805299]	7
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	molecular function	IMP[16079795]	18
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0016491	oxidoreductase activity	molecular function	IDA[15620353]	21
GO:0008283	cell proliferation	biological process	IEA	66
GO:0005667	transcription factor complex	cellular component	ISS	52
GO:0046886	positive regulation of hormone biosynthetic process	biological process	IEA	1
GO:0055001	muscle cell development	biological process	ISS	3
GO:0001701	in utero embryonic development	biological process	IEA	39
GO:0050660	flavin adenine dinucleotide binding	molecular function	IDA[15620353]	15
GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)	molecular function	IDA	1
GO:0032454	histone demethylase activity (H3-K9 specific)	molecular function	IDA[16079795]	2
GO:0001085	RNA polymerase II transcription factor binding	molecular function	IEA	11
GO:0010725	regulation of primitive erythrocyte differentiation	biological process	IEA	1
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	biological process	IMP[17805299]	2
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological process	IMP[17805299]; ISS	90
GO:0006482	protein demethylation	biological process	IMP[17805299]	3
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological process	IDA	141
GO:0006357	regulation of transcription from RNA polymerase II promoter	biological process	IMP[16079795]	46
GO:2000179	positive regulation of neural precursor cell proliferation	biological process	IEA	2
GO:0005515	protein binding	molecular function	IPI	1015
GO:0033169	histone H3-K9 demethylation	biological process	IDA[16079795]	1
GO:0032453	histone demethylase activity (H3-K4 specific)	molecular function	IDA[15620353]	1
GO:0005634	nucleus	cellular component	IDA[19497860]	877
GO:0051572	negative regulation of histone H3-K4 methylation	biological process	IEA	1
GO:0043426	MRF binding	molecular function	IDA	2
GO:0030851	granulocyte differentiation	biological process	IEA	4
GO:0007596	blood coagulation	biological process	TAS	85
GO:0043066	negative regulation of apoptotic process	biological process	IMP[17805299]	85
GO:0043392	negative regulation of DNA binding	biological process	IC[17805299]	6
GO:0050681	androgen receptor binding	molecular function	IDA[16079795]	9
GO:0003682	chromatin binding	molecular function	IDA	50

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KDM1A (count: 125)

Gene Symbol	Pathway Count	Pathway List
GATA6	14	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; blood coagulation; negative regulation of apoptotic process; chromatin binding;
CREBBP	12	sequence-specific DNA binding transcription factor activity; transcription factor binding; p53 binding; nuclear chromatin; transcription factor complex; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding; nucleus; MRF binding; chromatin binding;
RELA	11	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process; chromatin binding;
HINFP	10	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; enzyme binding; transcription, DNA-dependent; in utero embryonic development; nucleoplasm; protein binding; nucleus; chromatin binding;
MEN1	10	transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
HMGA1	10	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; transcription factor complex; nucleoplasm; protein binding; nucleus;
MTA2	9	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
YAP1	9	transcription regulatory region DNA binding; cell proliferation; transcription factor complex; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process; chromatin binding;
MYB	9	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; blood coagulation; chromatin binding;
ETS1	9	sequence-specific DNA binding transcription factor activity; transcription factor binding; positive regulation of erythrocyte differentiation; pituitary gland development; transcription, DNA-dependent; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
MED1	9	transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process; chromatin binding;
HNF1B	8	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
KLF4	8	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nuclear chromatin; transcription factor complex; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
XRCC5	8	transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; cell proliferation; nucleoplasm; protein binding; nucleus; negative regulation of apoptotic process;
FOXC2	8	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus; negative regulation of apoptotic process;
SOX8	8	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; nucleus; negative regulation of apoptotic process;
SREBF1	8	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
CBFA2T3	8	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; cell proliferation; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; granulocyte differentiation; chromatin binding;
SPI1	8	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nuclear chromatin; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; granulocyte differentiation;
SMARCD3	8	transcription factor binding; nuclear chromatin; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleoplasm; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
ZFPM1	8	transcription factor binding; negative regulation of protein binding; transcription factor complex; RNA polymerase II transcription factor binding; nucleoplasm; protein binding; granulocyte differentiation; blood coagulation;
DAXX	8	transcription factor binding; negative regulation of transcription, DNA-dependent; p53 binding; enzyme binding; transcription, DNA-dependent; protein binding; nucleus; androgen receptor binding;
KAT5	8	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; androgen receptor binding;
GSK3B	8	negative regulation of transcription, DNA-dependent; negative regulation of protein binding; p53 binding; RNA polymerase II transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
SMARCB1	8	p53 binding; positive regulation of sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
NCOA6	8	enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription factor complex; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
CIITA	7	transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding;
FOXF1	7	transcription regulatory region DNA binding; transcription factor binding; transcription factor complex; in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
HOXA7	7	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
POU2F3	7	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
RBPJ	7	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
TFAP2B	7	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
HIRA	7	sequence-specific DNA binding transcription factor activity; nuclear chromatin; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
FOXE1	7	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
HES1	7	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
HEY2	7	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
STRN3	7	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
UBE2I	7	transcription factor binding; negative regulation of transcription, DNA-dependent; enzyme binding; positive regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
FOXP1	7	transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; nucleus; chromatin binding;
TLE1	7	transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; nucleoplasm; protein binding; nucleus; chromatin binding;
DAB2	7	negative regulation of transcription, DNA-dependent; negative regulation of protein binding; cell proliferation; in utero embryonic development; protein binding; nucleus; negative regulation of apoptotic process;
SNW1	7	negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
ID2	7	negative regulation of transcription, DNA-dependent; positive regulation of erythrocyte differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of DNA binding;
VEGFA	7	in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; blood coagulation; negative regulation of apoptotic process;
ARRB1	6	transcription regulatory region DNA binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; blood coagulation;
TFAP4	6	transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; protein binding; nucleus; negative regulation of apoptotic process; negative regulation of DNA binding;
GLIS2	6	transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
ZNF174	6	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus;
TFEB	6	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; nucleus;
ATF6	6	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; nucleoplasm; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
MEIS2	6	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
E4F1	6	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding;
BARX2	6	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; transcription factor complex; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; chromatin binding;
MKL2	6	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
FOSL1	6	sequence-specific DNA binding transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; in utero embryonic development; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
TBX1	6	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; nucleus;
ISL1	6	sequence-specific DNA binding transcription factor activity; pituitary gland development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus; chromatin binding;
HOXA9	6	sequence-specific DNA binding transcription factor activity; enzyme binding; transcription, DNA-dependent; transcription factor complex; protein binding; nucleus;
GATAD2A	6	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; in utero embryonic development; protein binding; nucleus;
MAPK1	6	transcription factor binding; transcription, DNA-dependent; nucleoplasm; protein binding; nucleus; blood coagulation;
KAT8	6	transcription factor binding; negative regulation of transcription, DNA-dependent; enzyme binding; transcription, DNA-dependent; protein binding; nucleus;
FOXG1	6	transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
ATXN1	6	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
PHF2	6	histone demethylase activity; transcription, DNA-dependent; histone demethylase activity (H3-K9 specific); protein demethylation; protein binding; nucleus;
TP53BP1	6	p53 binding; positive regulation of sequence-specific DNA binding transcription factor activity; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
AXIN1	6	p53 binding; enzyme binding; muscle cell development; in utero embryonic development; protein binding; nucleus;
NR5A1	6	enzyme binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
TXN	6	enzyme binding; transcription, DNA-dependent; cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding;
MED17	6	ligand-dependent nuclear receptor transcription coactivator activity; transcription factor complex; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; nucleus;
NRIP1	6	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; androgen receptor binding;
LPIN1	6	transcription, DNA-dependent; transcription factor complex; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
NCOR2	6	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding; nucleus; chromatin binding;
GFI1B	6	cell proliferation; transcription factor complex; RNA polymerase II transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
PLK1	6	cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding; nucleus; negative regulation of apoptotic process;
KMT2A	5	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
HOXA13	5	transcription regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nucleus;
IKZF1	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
FOXD4	5	sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; nucleus;
HOXA1	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
NEUROD2	5	sequence-specific DNA binding transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; nucleus;
AATF	5	sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
FOXP2	5	sequence-specific DNA binding transcription factor activity; transcription factor binding; negative regulation of transcription, DNA-dependent; transcription factor complex; chromatin binding;
HES6	5	sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription, DNA-dependent; transcription factor complex; regulation of transcription from RNA polymerase II promoter;
TCF25	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
DRAP1	5	sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus;
TAF10	5	sequence-specific DNA binding transcription factor activity; enzyme binding; nucleoplasm; protein binding; nucleus;
BSX	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; nucleus;
ZNF24	5	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus;
LMX1B	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; in utero embryonic development; protein binding; nucleus;
CREBZF	5	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus;
RCOR2	5	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcription factor complex; chromatin binding;
HOXA2	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; nucleus;
CLOCK	5	sequence-specific DNA binding transcription factor activity; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; nucleus;
HOXA5	5	sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
ELK3	5	sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus;
APBB1	5	transcription factor binding; transcription, DNA-dependent; protein binding; nucleus; chromatin binding;
DNAJA3	5	transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
RSF1	5	negative regulation of transcription, DNA-dependent; nucleoplasm; protein binding; nucleus; negative regulation of DNA binding;
EED	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; chromatin binding;
NIPBL	5	negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
CBX3	5	negative regulation of transcription, DNA-dependent; enzyme binding; transcription, DNA-dependent; protein binding; nucleus;
H2AFX	5	nuclear chromatin; enzyme binding; nucleoplasm; protein binding; nucleus;
RCC1	5	nuclear chromatin; nucleoplasm; protein binding; nucleus; chromatin binding;
WWOX	5	enzyme binding; oxidoreductase activity; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
MED14	5	ligand-dependent nuclear receptor transcription coactivator activity; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; nucleus;
RBM14	5	ligand-dependent nuclear receptor transcription coactivator activity; transcription factor complex; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
NCOA7	5	ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
MED12	5	ligand-dependent nuclear receptor transcription coactivator activity; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; nucleus; chromatin binding;
SS18	5	ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
SUB1	5	transcription, DNA-dependent; transcription factor complex; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
NEDD4L	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein binding; nucleus;
NSD1	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus; androgen receptor binding; chromatin binding;
UBB	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding;
HABP4	5	transcription, DNA-dependent; protein binding; nucleus; blood coagulation; negative regulation of DNA binding;
NR4A2	5	transcription, DNA-dependent; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
PRKAA1	5	transcription, DNA-dependent; protein binding; nucleus; negative regulation of apoptotic process; chromatin binding;
UTF1	5	transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
RNF2	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; chromatin binding;
UBC	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding;
FLCN	5	in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
IRF7	5	negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus;
MAP2K5	5	negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
MAPK3	5	nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; blood coagulation;
MAPK7	5	nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; negative regulation of apoptotic process;
PRPF6	5	nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleus; androgen receptor binding;

Genes shared at least 2 KEGG pathways with KDM1A (count: 0)

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Region: chr1:23345941..23410182 View in gBrowse