ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RCC1
Previous Symbol	CHC1
Approved Name	regulator of chromosome condensation 1
Previous Name	chromosome condensation 1
Location	1p35.3
Position	chr1:28832455-28865708, +
External Links	HGNC: 1913 Entrez Gene: 1104 Ensembl: ENSG00000180198 UCSC: uc001bqf.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 22)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

GO terms by database search (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process	IMP[3678831]	26
GO:0000790	nuclear chromatin	Cellular Component	IDA[15014043]	11
GO:0000794	condensed nuclear chromosome	Cellular Component	IDA[15014043]	6
GO:0003682	chromatin binding	Molecular Function	IDA[2677018]	48
GO:0005087	Ran guanyl-nucleotide exchange factor activity	Molecular Function	IDA[1944575]	2
GO:0005515	protein binding	Molecular Function	IPI[18617507]	910
GO:0005634	nucleus	Cellular Component		770
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component	IDA[17435751]	690
GO:0007052	mitotic spindle organization	Biological Process	IDA[15014043]	7
GO:0007090	regulation of S phase of mitotic cell cycle	Biological Process	IMP[3678831]	2
GO:0007088	regulation of mitosis	Biological Process	IDA[15014043]	1
GO:0007067	mitosis	Biological Process		39
GO:0007059	chromosome segregation	Biological Process	IMP[17435751]	14
GO:0042393	histone binding	Molecular Function	IDA[11375490]	9
GO:0031965	nuclear membrane	Cellular Component		27
GO:0031492	nucleosomal DNA binding	Molecular Function	IDA[17435751]	1
GO:0016032	viral reproduction	Biological Process		57
GO:0051301	cell division	Biological Process		58
GO:0051225	spindle assembly	Biological Process	IMP[17435751]	4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RCC1 (count: 65)

Gene Symbol	Pathway Count	Pathway List
SMC1A	10	microtubule cytoskeleton organization; condensed nuclear chromosome; chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm; mitotic spindle organization; cell division;
CDCA5	9	G1/S transition of mitotic cell cycle; nuclear chromatin; chromatin binding; protein binding; nucleus; nucleolus; cytoplasm; mitosis; cell division;
RAN	9	microtubule cytoskeleton organization; chromatin binding; protein binding; nucleoplasm; cytoplasm; mitotic spindle organization; mitosis; viral reproduction; cell division;
SMC3	9	microtubule cytoskeleton organization; chromatin binding; protein binding; nucleus; nucleoplasm; cytoplasm; mitotic spindle organization; mitosis; cell division;
HINFP	7	G1/S transition of mitotic cell cycle; chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus; histone binding;
NCOR1	7	nuclear chromatin; chromatin binding; protein binding; nucleus; nucleoplasm; cytoplasm; spindle assembly;
SSRP1	7	chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm; viral reproduction;
PSMC3	6	G1/S transition of mitotic cell cycle; protein binding; nucleus; nucleoplasm; cytoplasm; viral reproduction;
KIF2C	6	microtubule cytoskeleton organization; protein binding; nucleus; mitosis; chromosome segregation; cell division;
PAFAH1B1	6	microtubule cytoskeleton organization; protein binding; nucleus; nucleolus; cytoplasm; nuclear membrane;
H2AFX	6	nuclear chromatin; condensed nuclear chromosome; protein binding; nucleus; nucleoplasm; histone binding;
MEN1	6	chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
CEP164	6	protein binding; nucleus; nucleolus; cytoplasm; mitosis; cell division;
NEK6	6	protein binding; nucleus; cytoplasm; mitosis; chromosome segregation; spindle assembly;
NUMA1	6	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm; cell division;
PTTG1	6	protein binding; nucleus; cytoplasm; mitosis; chromosome segregation; cell division;
XRCC5	6	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm; viral reproduction;
CCND1	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; nucleoplasm; cell division;
CDC45	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; nucleoplasm; cytoplasm;
CDT1	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; nucleoplasm; regulation of S phase of mitotic cell cycle;
LATS2	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
POLA2	5	G1/S transition of mitotic cell cycle; nucleus; nucleoplasm; nucleolus; cytoplasm;
RBBP8	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
USP37	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
KIF11	5	microtubule cytoskeleton organization; cytoplasm; mitotic spindle organization; mitosis; cell division;
PRC1	5	microtubule cytoskeleton organization; protein binding; nucleus; nucleolus; cytoplasm;
UXT	5	microtubule cytoskeleton organization; chromatin binding; protein binding; nucleus; cytoplasm;
KDM1A	5	nuclear chromatin; chromatin binding; protein binding; nucleus; nucleoplasm;
SMARCD3	5	nuclear chromatin; protein binding; nucleus; nucleoplasm; cytoplasm;
APBB1	5	chromatin binding; protein binding; nucleus; cytoplasm; histone binding;
MED1	5	chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus;
NCOA6	5	chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus;
NCOR2	5	chromatin binding; protein binding; nucleus; nucleoplasm; nucleolus;
NUP62	5	chromatin binding; protein binding; cytoplasm; nuclear membrane; viral reproduction;
PRKCB	5	chromatin binding; protein binding; nucleus; cytoplasm; histone binding;
RELA	5	chromatin binding; protein binding; nucleus; nucleoplasm; cytoplasm;
RNF20	5	chromatin binding; protein binding; nucleus; nucleolus; histone binding;
TFAP2A	5	chromatin binding; protein binding; nucleus; nucleolus; cytoplasm;
YAP1	5	chromatin binding; protein binding; nucleus; nucleoplasm; cytoplasm;
SERGEF	5	Ran guanyl-nucleotide exchange factor activity; protein binding; nucleus; nucleolus; cytoplasm;
ATXN1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
CENPW	5	protein binding; nucleolus; mitosis; chromosome segregation; cell division;
DGCR8	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
DHX9	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
EFTUD2	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
FUS	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
HNRNPA2B1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
HNRNPH1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
MAPK1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
PGR	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
PPP1CA	5	protein binding; nucleus; nucleolus; cytoplasm; cell division;
RAD23B	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RAD9A	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RBM4	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RBPJ	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RFWD2	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
SAC3D1	5	protein binding; cytoplasm; mitosis; cell division; spindle assembly;
SART1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
SKA3	5	protein binding; cytoplasm; mitosis; chromosome segregation; cell division;
TAF10	5	protein binding; nucleus; nucleoplasm; cytoplasm; viral reproduction;
TAF13	5	protein binding; nucleus; nucleoplasm; nucleolus; viral reproduction;
XPO1	5	protein binding; nucleoplasm; nucleolus; cytoplasm; viral reproduction;
CENPV	5	nucleus; nucleolus; cytoplasm; mitosis; cell division;
LRRCC1	5	nucleus; nucleolus; cytoplasm; mitosis; cell division;
TAF4B	5	nucleus; nucleoplasm; nucleolus; cytoplasm; viral reproduction;

Genes shared at least 2 KEGG pathways with RCC1 (count: 0)

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Region: chr1:28832455..28865708 View in gBrowse