ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TFAP2A
Previous Symbol	TFAP2, AP2TF
Symbol Alias	AP-2
Approved Name	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Previous Name	transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)
Location	6pter-p22.3
Position	chr6:10393419-10419892, -
External Links	HGNC: 11742 Entrez Gene: 7020 Ensembl: ENSG00000137203 UCSC: uc003myr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lionel[2011]_14	chr6:0-0 (NCBI36 / hg18)	262	6p24.2	Gain	M

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 70)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 70)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0014032	neural crest cell development	Biological Process		3
GO:0021506	anterior neuropore closure	Biological Process		1
GO:0010842	retina layer formation	Biological Process		3
GO:0010944	negative regulation of transcription by competitive promoter binding	Biological Process	IDA[8321221]; IMP[11278550]	1
GO:0010172	embryonic body morphogenesis	Biological Process		2
GO:0010628	positive regulation of gene expression	Biological Process		28
GO:0008285	negative regulation of cell proliferation	Biological Process		59
GO:0009880	embryonic pattern specification	Biological Process		5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	Biological Process		6
GO:0042472	inner ear morphogenesis	Biological Process		6
GO:0030501	positive regulation of bone mineralization	Biological Process	IDA[19578371]	3
GO:0035115	embryonic forelimb morphogenesis	Biological Process		4
GO:0021884	forebrain neuron development	Biological Process		2
GO:0030335	positive regulation of cell migration	Biological Process		29
GO:0021559	trigeminal nerve development	Biological Process		2
GO:0021623	oculomotor nerve formation	Biological Process		2
GO:0045595	regulation of cell differentiation	Biological Process		6
GO:0044212	transcription regulatory region DNA binding	Molecular Function	IDA[12586840]	23
GO:0043588	skin development	Biological Process		7
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA[8321221]	72
GO:0043525	positive regulation of neuron apoptotic process	Biological Process		9
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0043066	negative regulation of apoptotic process	Biological Process		77
GO:0042803	protein homodimerization activity	Molecular Function	TAS[7559606]	113
GO:0048730	epidermis morphogenesis	Biological Process		3
GO:0048701	embryonic cranial skeleton morphogenesis	Biological Process		3
GO:0048485	sympathetic nervous system development	Biological Process		5
GO:0046983	protein dimerization activity	Molecular Function	IDA[12072434]	26
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[7559606]	131
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA[12586840]	80
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process		64
GO:0045664	regulation of neuron differentiation	Biological Process		4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[8321221]	78
GO:0000976	transcription regulatory region sequence-specific DNA binding	Molecular Function	IDA[18718911]	4
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular Function	IDA[9520389]	4
GO:0000987	core promoter proximal region sequence-specific DNA binding	Molecular Function	IDA[7559606]	2
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular Function	IDA[11278550]	8
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular Function	IDA[9520389]	7
GO:0001105	RNA polymerase II transcription coactivator activity	Molecular Function		2
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	Molecular Function	IDA[7555706]	6
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular Function		3
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular Function	IDA[7555706]	6
GO:0000982	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity	Molecular Function		3
GO:0003409	optic cup structural organization	Biological Process		1
GO:0003404	optic vesicle morphogenesis	Biological Process		1
GO:0003713	transcription coactivator activity	Molecular Function	IDA[7555706]	52
GO:0003682	chromatin binding	Molecular Function		48
GO:0001822	kidney development	Biological Process		16
GO:0001106	RNA polymerase II transcription corepressor activity	Molecular Function		3
GO:0003334	keratinocyte development	Biological Process		1
GO:0003151	outflow tract morphogenesis	Biological Process		12
GO:0005813	centrosome	Cellular Component		71
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0007605	sensory perception of sound	Biological Process		31
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	IDA[7555706]	62
GO:0005634	nucleus	Cellular Component	IMP[12586840]	770
GO:0005515	protein binding	Molecular Function	IPI[12586840]	910
GO:0005737	cytoplasm	Cellular Component		690
GO:0005730	nucleolus	Cellular Component		243
GO:0060021	palate development	Biological Process		5
GO:0060235	lens induction in camera-type eye	Biological Process		1
GO:0060325	face morphogenesis	Biological Process		5
GO:0060349	bone morphogenesis	Biological Process		4
GO:0061029	eyelid development in camera-type eye	Biological Process		1
GO:0061303	cornea development in camera-type eye	Biological Process		2
GO:0070172	positive regulation of tooth mineralization	Biological Process	IDA[19578371]	2
GO:0071281	cellular response to iron ion	Biological Process		1
GO:0071711	basement membrane organization	Biological Process		1
GO:0072210	metanephric nephron development	Biological Process		1
GO:2000378	negative regulation of reactive oxygen species metabolic process	Biological Process		4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TFAP2A (count: 157)

Gene Symbol	Pathway Count	Pathway List
MEN1	12	negative regulation of cell proliferation; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; cytoplasm; nucleolus; palate development;
MED1	11	positive regulation of gene expression; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus;
KLF4	11	negative regulation of cell proliferation; regulation of cell differentiation; transcription regulatory region DNA binding; epidermis morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; transcription from RNA polymerase II promoter;
TBX1	11	inner ear morphogenesis; sequence-specific DNA binding; protein homodimerization activity; embryonic cranial skeleton morphogenesis; protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; outflow tract morphogenesis; sensory perception of sound; nucleus; face morphogenesis;
GATA6	11	transcription regulatory region DNA binding; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; chromatin binding; transcription from RNA polymerase II promoter; nucleus; protein binding;
HNF1B	11	transcription regulatory region DNA binding; sequence-specific DNA binding; negative regulation of apoptotic process; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; kidney development; nucleus; protein binding; nucleolus;
VEGFA	10	positive regulation of gene expression; positive regulation of cell migration; negative regulation of apoptotic process; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; kidney development; outflow tract morphogenesis; protein binding; cytoplasm;
RELA	10	transcription regulatory region DNA binding; sequence-specific DNA binding; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; chromatin binding; nucleus; protein binding; cytoplasm;
HES1	10	sequence-specific DNA binding; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; outflow tract morphogenesis; nucleus; protein binding; cytoplasm;
RBPJ	10	positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; outflow tract morphogenesis; nucleus; protein binding; cytoplasm; nucleolus;
FOXC2	9	neural crest cell development; transcription regulatory region DNA binding; sequence-specific DNA binding; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; nucleus;
HINFP	9	positive regulation of gene expression; transcription regulatory region DNA binding; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus;
ID2	9	positive regulation of gene expression; protein dimerization activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm; nucleolus;
WNT11	9	positive regulation of gene expression; positive regulation of cell migration; transcription regulatory region DNA binding; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; outflow tract morphogenesis; cytoplasm; palate development;
APC	9	negative regulation of cell proliferation; positive regulation of cell migration; skin development; negative regulation of apoptotic process; kidney development; centrosome; nucleus; protein binding; cytoplasm;
NIPBL	9	embryonic forelimb morphogenesis; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; outflow tract morphogenesis; sensory perception of sound; nucleus; protein binding; face morphogenesis;
HEY2	9	sequence-specific DNA binding; protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; nucleus; protein binding; cytoplasm;
AATF	9	negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; centrosome; Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus; negative regulation of reactive oxygen species metabolic process;
IRF7	9	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
LHX1	8	retina layer formation; embryonic pattern specification; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; kidney development; transcription from RNA polymerase II promoter; nucleus;
ETS1	8	negative regulation of cell proliferation; positive regulation of cell migration; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; nucleus; protein binding;
ISL1	8	trigeminal nerve development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II transcription coactivator activity; chromatin binding; outflow tract morphogenesis; nucleus; cytoplasm;
KDM1A	8	transcription regulatory region DNA binding; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding;
MTA2	8	transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; nucleolus;
NCOR1	8	transcription regulatory region DNA binding; sequence-specific DNA binding; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
YAP1	8	transcription regulatory region DNA binding; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; chromatin binding; nucleus; protein binding; cytoplasm;
FOXP1	8	sequence-specific DNA binding; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; chromatin binding; nucleus; cytoplasm; nucleolus;
NCOA6	8	intracellular membrane-bounded organelle; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus;
GSK3B	8	negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; centrosome; nucleus; protein binding; cytoplasm; nucleolus;
TCF21	8	protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; kidney development; nucleus; palate development;
KAT5	8	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding; nucleolus;
NUP62	7	negative regulation of cell proliferation; intracellular membrane-bounded organelle; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; chromatin binding; protein binding; cytoplasm;
ZBTB16	7	negative regulation of cell proliferation; embryonic pattern specification; protein homodimerization activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleus; protein binding;
FOXF1	7	positive regulation of cell migration; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus;
MAPK1	7	positive regulation of cell migration; positive regulation of transcription, DNA-dependent; Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
CDK5RAP2	7	transcription regulatory region DNA binding; positive regulation of transcription, DNA-dependent; regulation of neuron differentiation; centrosome; Golgi apparatus; protein binding; cytoplasm;
MLL	7	transcription regulatory region DNA binding; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; nucleus; protein binding;
XRCC5	7	transcription regulatory region DNA binding; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm; nucleolus;
FOXE1	7	sequence-specific DNA binding; sympathetic nervous system development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus;
POU2F3	7	sequence-specific DNA binding; protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm; nucleolus;
SREBF1	7	sequence-specific DNA binding; protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding;
ATXN1	7	intracellular membrane-bounded organelle; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm; nucleolus;
CLOCK	7	intracellular membrane-bounded organelle; protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
THRAP3	7	intracellular membrane-bounded organelle; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription coactivator activity; nucleus; protein binding; nucleolus;
CRYAB	7	negative regulation of apoptotic process; protein homodimerization activity; Golgi apparatus; nucleus; protein binding; cytoplasm; negative regulation of reactive oxygen species metabolic process;
CEP57	7	protein homodimerization activity; centrosome; Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
HSF2	7	protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription from RNA polymerase II promoter; nucleus; cytoplasm; nucleolus;
SNW1	7	positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding; nucleolus;
STRN3	7	positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; Golgi apparatus; nucleus; protein binding; cytoplasm;
UXT	7	negative regulation of transcription from RNA polymerase II promoter; chromatin binding; RNA polymerase II transcription corepressor activity; centrosome; nucleus; protein binding; cytoplasm;
FLCN	6	positive regulation of gene expression; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
NFIL3	6	positive regulation of gene expression; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; transcription from RNA polymerase II promoter; nucleus;
FGF10	6	negative regulation of cell proliferation; embryonic pattern specification; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nucleus;
KLF11	6	negative regulation of cell proliferation; transcription regulatory region DNA binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter; nucleus;
SMARCB1	6	negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding; nucleolus;
TGFB1I1	6	negative regulation of cell proliferation; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter; protein binding; cytoplasm;
FOXG1	6	inner ear morphogenesis; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleus; protein binding;
DAB2	6	positive regulation of cell migration; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleus; protein binding;
TRIM32	6	positive regulation of cell migration; negative regulation of apoptotic process; transcription coactivator activity; nucleus; protein binding; cytoplasm;
ARRB1	6	transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
CREB5	6	sequence-specific DNA binding; positive regulation of transcription, DNA-dependent; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; transcription from RNA polymerase II promoter; nucleus; protein binding;
MAF	6	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nucleus; cytoplasm;
MEIS2	6	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nucleus; protein binding;
MTA3	6	sequence-specific DNA binding; intracellular membrane-bounded organelle; chromatin binding; nucleus; cytoplasm; nucleolus;
NR5A1	6	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; chromatin binding; nucleus; protein binding;
PGR	6	sequence-specific DNA binding; intracellular membrane-bounded organelle; nucleus; protein binding; cytoplasm; nucleolus;
MAML1	6	intracellular membrane-bounded organelle; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding; nucleolus;
KLHL20	6	negative regulation of apoptotic process; Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
TGFBR1	6	negative regulation of apoptotic process; embryonic cranial skeleton morphogenesis; positive regulation of transcription, DNA-dependent; kidney development; protein binding; palate development;
CRYM	6	protein homodimerization activity; negative regulation of transcription from RNA polymerase II promoter; sensory perception of sound; nucleus; cytoplasm; nucleolus;
DAXX	6	protein homodimerization activity; negative regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm; nucleolus;
PAFAH1B1	6	protein homodimerization activity; centrosome; nucleus; protein binding; cytoplasm; nucleolus;
PDE2A	6	protein homodimerization activity; negative regulation of transcription from RNA polymerase II promoter; Golgi apparatus; nucleus; protein binding; cytoplasm;
TRIM5	6	protein homodimerization activity; Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
WWOX	6	protein dimerization activity; positive regulation of transcription from RNA polymerase II promoter; Golgi apparatus; nucleus; protein binding; cytoplasm;
MYB	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; chromatin binding; protein binding;
NRIP1	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding;
SPI1	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II distal enhancer sequence-specific DNA binding; protein binding;
RNF20	6	positive regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus;
SSRP1	6	chromatin binding; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm; nucleolus;
AHI1	5	retina layer formation; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; centrosome; protein binding;
PRDM1	5	positive regulation of gene expression; sequence-specific DNA binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; cytoplasm;
PRKAA1	5	positive regulation of gene expression; negative regulation of apoptotic process; chromatin binding; nucleus; protein binding;
HMGA1	5	negative regulation of cell proliferation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleus; protein binding;
KLF13	5	negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nucleus; protein binding;
NF2	5	negative regulation of cell proliferation; nucleus; protein binding; cytoplasm; nucleolus;
ROR2	5	negative regulation of cell proliferation; inner ear morphogenesis; positive regulation of cell migration; positive regulation of transcription, DNA-dependent; protein binding;
TSC1	5	negative regulation of cell proliferation; intracellular membrane-bounded organelle; kidney development; protein binding; cytoplasm;
CBL	5	negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of apoptotic process; nucleus; protein binding; cytoplasm;
DAB2IP	5	negative regulation of epidermal growth factor receptor signaling pathway; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cytoplasm;
ADRB2	5	positive regulation of bone mineralization; protein homodimerization activity; positive regulation of transcription from RNA polymerase II promoter; nucleus; protein binding;
HOXA13	5	embryonic forelimb morphogenesis; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; nucleus;
HOXA9	5	embryonic forelimb morphogenesis; sequence-specific DNA binding; nucleus; protein binding; cytoplasm;
CORO1A	5	positive regulation of cell migration; protein homodimerization activity; nucleus; protein binding; cytoplasm;
BIRC2	5	regulation of cell differentiation; negative regulation of apoptotic process; transcription coactivator activity; nucleus; protein binding;
FOXD4	5	sequence-specific DNA binding; sympathetic nervous system development; positive regulation of transcription from RNA polymerase II promoter; nucleus; nucleolus;
FOXP2	5	sequence-specific DNA binding; protein homodimerization activity; negative regulation of transcription, DNA-dependent; chromatin binding; cytoplasm;
HOXA1	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; sensory perception of sound; nucleus; protein binding;
HOXA2	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; nucleus; nucleolus;
HOXA7	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; nucleus;
HOXB1	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; nucleus; cytoplasm; nucleolus;
IKZF1	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; nucleus; cytoplasm;
NR4A2	5	sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
MAP3K11	5	positive regulation of neuron apoptotic process; protein homodimerization activity; centrosome; protein binding; cytoplasm;
DPF2	5	intracellular membrane-bounded organelle; centrosome; nucleus; cytoplasm; nucleolus;
ELK3	5	intracellular membrane-bounded organelle; negative regulation of transcription, DNA-dependent; nucleus; protein binding; nucleolus;
G2E3	5	intracellular membrane-bounded organelle; negative regulation of apoptotic process; Golgi apparatus; cytoplasm; nucleolus;
PICALM	5	intracellular membrane-bounded organelle; positive regulation of transcription, DNA-dependent; Golgi apparatus; nucleus; protein binding;
PRDX5	5	intracellular membrane-bounded organelle; negative regulation of apoptotic process; protein dimerization activity; nucleus; cytoplasm;
SCAMP2	5	intracellular membrane-bounded organelle; Golgi apparatus; nucleus; protein binding; nucleolus;
STAP1	5	intracellular membrane-bounded organelle; nucleus; protein binding; cytoplasm; nucleolus;
STX16	5	intracellular membrane-bounded organelle; Golgi apparatus; protein binding; cytoplasm; nucleolus;
BARD1	5	negative regulation of apoptotic process; protein homodimerization activity; nucleus; protein binding; cytoplasm;
BIRC3	5	negative regulation of apoptotic process; nucleus; protein binding; cytoplasm; negative regulation of reactive oxygen species metabolic process;
BNIP3	5	negative regulation of apoptotic process; protein homodimerization activity; nucleus; protein binding; cytoplasm;
MALT1	5	negative regulation of apoptotic process; nucleus; protein binding; cytoplasm; nucleolus;
PLK1	5	negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; centrosome; nucleus; protein binding;
SNCA	5	negative regulation of apoptotic process; Golgi apparatus; nucleus; protein binding; cytoplasm;
TNFAIP3	5	negative regulation of apoptotic process; centrosome; nucleus; protein binding; cytoplasm;
FZD4	5	protein homodimerization activity; positive regulation of transcription, DNA-dependent; sensory perception of sound; protein binding; cytoplasm;
RCHY1	5	protein homodimerization activity; nucleus; protein binding; cytoplasm; nucleolus;
RNF40	5	protein homodimerization activity; nucleus; protein binding; cytoplasm; nucleolus;
NPAS3	5	protein dimerization activity; positive regulation of transcription, DNA-dependent; nucleus; cytoplasm; nucleolus;
LPIN1	5	positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; cytoplasm;
MAPK3	5	positive regulation of transcription from RNA polymerase II promoter; Golgi apparatus; nucleus; protein binding; nucleolus;
MED12	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; nucleus;
NFATC4	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription coactivator activity; transcription from RNA polymerase II promoter; cytoplasm;
PRKD1	5	positive regulation of transcription from RNA polymerase II promoter; Golgi apparatus; nucleus; protein binding; cytoplasm;
RPS6KA4	5	positive regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm; nucleolus;
TP53BP1	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm;
UBE3A	5	positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; protein binding; cytoplasm;
APBB1	5	positive regulation of transcription, DNA-dependent; chromatin binding; nucleus; protein binding; cytoplasm;
MED4	5	positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; nucleus; protein binding; nucleolus;
MMS19	5	positive regulation of transcription, DNA-dependent; transcription coactivator activity; nucleus; protein binding; cytoplasm;
RAN	5	positive regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; protein binding; cytoplasm;
RREB1	5	positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; nucleus; cytoplasm;
SMARCD3	5	positive regulation of transcription, DNA-dependent; transcription coactivator activity; nucleus; protein binding; cytoplasm;
SUPT3H	5	positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter; nucleus; nucleolus;
BCLAF1	5	negative regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm; nucleolus;
CCDC85B	5	negative regulation of transcription, DNA-dependent; centrosome; nucleus; protein binding; cytoplasm;
PDCD4	5	negative regulation of transcription, DNA-dependent; nucleus; protein binding; cytoplasm; nucleolus;
PER1	5	negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; RNA polymerase II core promoter proximal region sequence-specific DNA binding; nucleus; cytoplasm;
NCOR2	5	negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; nucleolus;
RNF2	5	negative regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; nucleolus;
TCF25	5	negative regulation of transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm; nucleolus;
AIP	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; nucleolus;
TAF10	5	transcription coactivator activity; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
CDCA5	5	chromatin binding; nucleus; protein binding; cytoplasm; nucleolus;
RCC1	5	chromatin binding; nucleus; protein binding; cytoplasm; nucleolus;
SMC1A	5	chromatin binding; nucleus; protein binding; cytoplasm; nucleolus;
CEP164	5	centrosome; nucleus; protein binding; cytoplasm; nucleolus;
DHX9	5	centrosome; nucleus; protein binding; cytoplasm; nucleolus;
FLII	5	centrosome; nucleus; protein binding; cytoplasm; nucleolus;
RFWD2	5	centrosome; nucleus; protein binding; cytoplasm; nucleolus;
ATXN2	5	Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
COG3	5	Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;
SART1	5	Golgi apparatus; nucleus; protein binding; cytoplasm; nucleolus;

Genes shared at least 2 KEGG pathways with TFAP2A (count: 0)

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Region: chr6:10393419..10419892 View in gBrowse