ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	HOXA13
Previous Symbol	HOX1J, HOX1
Approved Name	homeobox A13
Previous Name	homeo box A13
Location	7p15.2
Position	chr7:27233122-27239725, -
External Links	HGNC: 5102 Entrez Gene: 3209 Ensembl: ENSG00000106031 UCSC: uc003szb.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001501	skeletal system development	Biological Process	TAS[9020844]	16
GO:0001570	vasculogenesis	Biological Process		10
GO:0001886	endothelial cell morphogenesis	Biological Process		2
GO:0001894	tissue homeostasis	Biological Process		6
GO:0003281	ventricular septum development	Biological Process		5
GO:0003677	DNA binding	Molecular Function	TAS[9020844]	220
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0005634	nucleus	Cellular Component		770
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0030539	male genitalia development	Biological Process		4
GO:0030510	regulation of BMP signaling pathway	Biological Process		1
GO:0043065	positive regulation of apoptotic process	Biological Process		34
GO:0035115	embryonic forelimb morphogenesis	Biological Process		4
GO:0044212	transcription regulatory region DNA binding	Molecular Function		23
GO:0043565	sequence-specific DNA binding	Molecular Function		72
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0045840	positive regulation of mitosis	Biological Process		7
GO:0048844	artery morphogenesis	Biological Process		9
GO:0048839	inner ear development	Biological Process		5
GO:0060847	endothelial cell fate specification	Biological Process		1
GO:0060442	branching involved in prostate gland morphogenesis	Biological Process		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HOXA13 (count: 32)

Gene Symbol	Pathway Count	Pathway List
FOXC2	7	vasculogenesis; sequence-specific DNA binding transcription factor activity; nucleus; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; artery morphogenesis;
HES1	7	ventricular septum development; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; artery morphogenesis;
HOXA5	7	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; positive regulation of apoptotic process; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
TBX1	7	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; artery morphogenesis;
HOXA1	7	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; artery morphogenesis; inner ear development;
FOXF1	6	vasculogenesis; DNA binding; nucleus; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
ETS1	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HNF1B	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXB1	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
IKZF1	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
RELA	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
SREBF1	6	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
MEN1	6	nucleus; transcription, DNA-dependent; positive regulation of apoptotic process; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HEY2	5	vasculogenesis; sequence-specific DNA binding transcription factor activity; nucleus; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
CREBZF	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding;
DRAP1	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding;
FOXE1	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HINFP	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; transcription regulatory region DNA binding;
ZNF24	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding;
BSX	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA2	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA7	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA9	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; embryonic forelimb morphogenesis; sequence-specific DNA binding;
KDM1A	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
LHX2	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
MAF	5	sequence-specific DNA binding transcription factor activity; nucleus; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; inner ear development;
MTA2	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
NCOR1	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; transcription regulatory region DNA binding; sequence-specific DNA binding;
ONECUT2	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
POU2F3	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
TFEB	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
TFAP2A	5	nucleus; embryonic forelimb morphogenesis; transcription regulatory region DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;

Genes shared at least 2 KEGG pathways with HOXA13 (count: 0)

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Region: chr7:27233122..27239725 View in gBrowse