ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MEN1
Approved Name	multiple endocrine neoplasia I
Name Alias	menin
Location	11q13
Position	chr11:64570986-64578766, -
External Links	HGNC: 7010 Entrez Gene: 4221 Ensembl: ENSG00000133895 UCSC: uc001obn.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 61)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 61)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0009411	response to UV	Biological Process	IDA[16690369]	5
GO:0010332	response to gamma radiation	Biological Process	IDA[12874027]	3
GO:0007420	brain development	Biological Process		33
GO:0008285	negative regulation of cell proliferation	Biological Process	IDA[15331604]	59
GO:0007050	cell cycle arrest	Biological Process		25
GO:0007179	transforming growth factor beta receptor signaling pathway	Biological Process		14
GO:0006367	transcription initiation from RNA polymerase II promoter	Biological Process		42
GO:0006974	response to DNA damage stimulus	Biological Process	IDA[16690369]	37
GO:0006338	chromatin remodeling	Biological Process		10
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005829	cytosol	Cellular Component	IDA[14508515]	447
GO:0006281	DNA repair	Biological Process	NAS[12874027]	62
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component		690
GO:0005634	nucleus	Cellular Component		770
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005515	protein binding	Molecular Function	IPI[14508515]	910
GO:0003690	double-stranded DNA binding	Molecular Function	IDA[15331604]	17
GO:0003682	chromatin binding	Molecular Function		48
GO:0002076	osteoblast development	Biological Process	IGI[15563473]	4
GO:0002051	osteoblast fate commitment	Biological Process		1
GO:0001933	negative regulation of protein phosphorylation	Biological Process	IDA[12226747]	5
GO:0001776	leukocyte homeostasis	Biological Process		1
GO:0000785	chromatin	Cellular Component	IDA[12874027]	13
GO:0000403	Y-form DNA binding	Molecular Function	IDA[15331604]	1
GO:0000400	four-way junction DNA binding	Molecular Function	IDA[15331604]	1
GO:0000165	MAPK cascade	Biological Process	IDA[12226747]	10
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[9989505]	78
GO:0046329	negative regulation of JNK cascade	Biological Process	IDA[12226747]	6
GO:0046621	negative regulation of organ growth	Biological Process		2
GO:0047485	protein N-terminus binding	Molecular Function	IPI[11526476]	23
GO:0048704	embryonic skeletal system morphogenesis	Biological Process		9
GO:0051781	positive regulation of cell division	Biological Process		11
GO:0051974	negative regulation of telomerase activity	Biological Process	IMP[12837246]	1
GO:0060021	palate development	Biological Process		5
GO:0060135	maternal process involved in female pregnancy	Biological Process		5
GO:0043565	sequence-specific DNA binding	Molecular Function		72
GO:0044212	transcription regulatory region DNA binding	Molecular Function		23
GO:0045668	negative regulation of osteoblast differentiation	Biological Process	IGI[15563473]	6
GO:0045669	positive regulation of osteoblast differentiation	Biological Process		6
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	Biological Process	IMP[15640349]	6
GO:0045786	negative regulation of cell cycle	Biological Process	IDA[15331604]	9
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	IDA[12226747]	64
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0032925	regulation of activin receptor signaling pathway	Biological Process		2
GO:0032154	cleavage furrow	Cellular Component	IDA[14508515]	8
GO:0035097	histone methyltransferase complex	Cellular Component	IDA[17500065]; IPI[14992727]	4
GO:0034968	histone lysine methylation	Biological Process	IDA[14992727]	1
GO:0043234	protein complex	Cellular Component	IDA[15199122]	45
GO:0043065	positive regulation of apoptotic process	Biological Process		34
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	Biological Process	IDA[12226747]	6
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological Process		7
GO:0016363	nuclear matrix	Cellular Component	IDA[12874027]	16
GO:0010467	gene expression	Biological Process		140
GO:0030097	hemopoiesis	Biological Process		8
GO:0018024	histone-lysine N-methyltransferase activity	Molecular Function	IDA[14992727]	4
GO:0030674	protein binding, bridging	Molecular Function		11
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Biological Process	IMP[11274402]	6
GO:0032092	positive regulation of protein binding	Biological Process		4
GO:0031062	positive regulation of histone methylation	Biological Process		2
GO:0070412	R-SMAD binding	Molecular Function	IPI[11274402]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MEN1 (count: 244)

Gene Symbol	Pathway Count	Pathway List
NCOR1	13	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of JNK cascade; sequence-specific DNA binding; transcription regulatory region DNA binding; gene expression;
TFAP2A	12	negative regulation of cell proliferation; nucleolus; cytoplasm; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; palate development; sequence-specific DNA binding; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
SNW1	12	transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; nucleoplasm; protein binding; chromatin; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nuclear matrix; gene expression; positive regulation of transforming growth factor beta receptor signaling pathway;
NCOA6	11	brain development; transcription initiation from RNA polymerase II promoter; response to DNA damage stimulus; DNA repair; nucleolus; nucleus; nucleoplasm; protein binding; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; histone methyltransferase complex;
NCOR2	11	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; nucleolus; nucleus; nucleoplasm; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; protein N-terminus binding; gene expression;
YAP1	11	transcription initiation from RNA polymerase II promoter; response to DNA damage stimulus; cytosol; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
ID2	11	cytosol; nucleolus; cytoplasm; nucleus; protein binding; chromatin; negative regulation of transcription from RNA polymerase II promoter; negative regulation of osteoblast differentiation; negative regulation of transcription, DNA-dependent; protein complex; negative regulation of sequence-specific DNA binding transcription factor activity;
RELA	11	cytosol; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; protein N-terminus binding; sequence-specific DNA binding; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
MED1	10	brain development; transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; nucleoplasm; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; gene expression;
APC	10	negative regulation of cell proliferation; cell cycle arrest; response to DNA damage stimulus; cytosol; cytoplasm; nucleus; protein binding; positive regulation of cell division; negative regulation of cyclin-dependent protein kinase activity; positive regulation of apoptotic process;
NEDD4L	10	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytosol; cytoplasm; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; gene expression;
UBB	10	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytosol; DNA repair; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; gene expression;
UBC	10	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytosol; DNA repair; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; gene expression;
RBPJ	10	transcription initiation from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MAPK1	10	response to DNA damage stimulus; transcription, DNA-dependent; cytosol; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; MAPK cascade; protein complex;
KDM1A	10	transcription, DNA-dependent; nucleus; nucleoplasm; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of sequence-specific DNA binding transcription factor activity;
XRCC5	10	transcription, DNA-dependent; DNA repair; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; double-stranded DNA binding; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent;
NR4A2	9	transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytoplasm; nucleus; nucleoplasm; protein binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
NR5A1	9	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; double-stranded DNA binding; chromatin binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MAPK3	9	response to DNA damage stimulus; cytosol; nucleolus; nucleus; nucleoplasm; protein binding; MAPK cascade; positive regulation of transcription from RNA polymerase II promoter; gene expression;
ATXN1	9	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nuclear matrix;
HINFP	9	transcription, DNA-dependent; DNA repair; nucleolus; nucleus; nucleoplasm; protein binding; chromatin binding; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent;
KAT5	9	transcription, DNA-dependent; cytosol; nucleolus; nucleus; protein binding; chromatin; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
ERCC8	8	response to UV; response to DNA damage stimulus; DNA repair; nucleus; nucleoplasm; protein binding; protein complex; nuclear matrix;
ATM	8	brain development; cell cycle arrest; response to DNA damage stimulus; DNA repair; nucleoplasm; protein binding; protein N-terminus binding; positive regulation of apoptotic process;
NIPBL	8	brain development; response to DNA damage stimulus; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; protein N-terminus binding; negative regulation of transcription, DNA-dependent;
SMARCB1	8	negative regulation of cell proliferation; chromatin remodeling; transcription, DNA-dependent; nucleolus; nucleus; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter;
APBB1	8	cell cycle arrest; response to DNA damage stimulus; transcription, DNA-dependent; cytoplasm; nucleus; protein binding; chromatin binding; positive regulation of apoptotic process;
E2F5	8	transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; cytoplasm; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
XPO1	8	transforming growth factor beta receptor signaling pathway; cytosol; nucleolus; cytoplasm; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; gene expression;
PGR	8	transcription initiation from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; sequence-specific DNA binding; gene expression;
IRF7	8	response to DNA damage stimulus; cytosol; cytoplasm; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
RAD9A	8	response to DNA damage stimulus; DNA repair; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; positive regulation of apoptotic process;
MYB	8	chromatin remodeling; transcription, DNA-dependent; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nuclear matrix;
DAXX	8	transcription, DNA-dependent; cytosol; nucleolus; cytoplasm; nucleus; protein binding; protein N-terminus binding; negative regulation of transcription, DNA-dependent;
SREBF1	8	transcription, DNA-dependent; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; protein complex;
ARRB1	8	cytosol; cytoplasm; nucleus; protein binding; chromatin; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein binding;
GSK3B	8	cytosol; nucleolus; cytoplasm; nucleus; protein binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein binding;
RAN	8	cytosol; cytoplasm; nucleoplasm; protein binding; chromatin binding; chromatin; gene expression; positive regulation of protein binding;
SMC1A	8	DNA repair; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; gene expression;
SMC3	8	DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; chromatin; nuclear matrix;
SSRP1	8	DNA repair; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding; gene expression;
FOXP1	8	nucleolus; cytoplasm; nucleus; double-stranded DNA binding; chromatin binding; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
MTA2	8	nucleolus; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
FLCN	8	cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of apoptotic process; hemopoiesis; positive regulation of transforming growth factor beta receptor signaling pathway;
STRN3	8	cytoplasm; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; protein complex;
GATA6	8	nucleus; nucleoplasm; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
PMAIP1	7	response to UV; response to DNA damage stimulus; cytosol; nucleus; protein binding; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;
FOXG1	7	brain development; nucleus; protein binding; double-stranded DNA binding; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
ETS1	7	negative regulation of cell proliferation; transcription, DNA-dependent; nucleus; protein binding; sequence-specific DNA binding; negative regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter;
HMGA1	7	negative regulation of cell proliferation; transcription, DNA-dependent; cytosol; nucleus; nucleoplasm; protein binding; negative regulation of transcription, DNA-dependent;
TSC1	7	negative regulation of cell proliferation; cell cycle arrest; cytosol; cytoplasm; protein binding; protein N-terminus binding; protein complex;
ZBTB16	7	negative regulation of cell proliferation; transcription, DNA-dependent; nucleus; protein binding; negative regulation of transcription, DNA-dependent; positive regulation of apoptotic process; hemopoiesis;
BARD1	7	cell cycle arrest; response to DNA damage stimulus; DNA repair; cytoplasm; nucleus; protein binding; positive regulation of apoptotic process;
SART1	7	cell cycle arrest; cytosol; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding;
ESRRA	7	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MAML1	7	transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
CHD1L	7	response to DNA damage stimulus; chromatin remodeling; DNA repair; nucleolus; cytoplasm; nucleus; protein binding;
CHEK1	7	response to DNA damage stimulus; cytosol; DNA repair; nucleus; nucleoplasm; protein binding; chromatin;
MMS19	7	response to DNA damage stimulus; transcription, DNA-dependent; DNA repair; cytoplasm; nucleus; protein binding; protein binding, bridging;
MRE11A	7	response to DNA damage stimulus; DNA repair; nucleolus; nucleus; nucleoplasm; protein binding; double-stranded DNA binding;
TP53BP1	7	response to DNA damage stimulus; DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter;
USP28	7	response to DNA damage stimulus; DNA repair; nucleolus; nucleus; nucleoplasm; protein binding; protein complex;
BCLAF1	7	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding; negative regulation of transcription, DNA-dependent; positive regulation of apoptotic process;
HOXA2	7	transcription, DNA-dependent; nucleolus; nucleus; osteoblast development; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA5	7	transcription, DNA-dependent; nucleus; protein binding; embryonic skeletal system morphogenesis; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of apoptotic process;
HOXA7	7	transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter; embryonic skeletal system morphogenesis; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
HOXB1	7	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; embryonic skeletal system morphogenesis; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HSPA8	7	transcription, DNA-dependent; cytosol; nucleolus; nucleus; protein binding; negative regulation of transcription, DNA-dependent; gene expression;
POU2F3	7	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
NUMA1	7	cytosol; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; nuclear matrix;
PDCD4	7	cytosol; nucleolus; cytoplasm; nucleus; protein binding; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent;
HNF1B	7	nucleolus; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HES1	7	cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
HEY2	7	cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
ARRB2	6	brain development; transforming growth factor beta receptor signaling pathway; cytosol; cytoplasm; nucleus; protein binding;
UBE3A	6	brain development; cytosol; cytoplasm; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter;
KLF4	6	negative regulation of cell proliferation; double-stranded DNA binding; negative regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
NF2	6	negative regulation of cell proliferation; nucleolus; cytoplasm; nucleus; protein binding; cleavage furrow;
ILK	6	cell cycle arrest; cytosol; cytoplasm; protein binding; positive regulation of osteoblast differentiation; protein complex;
PRKAA1	6	cell cycle arrest; transcription, DNA-dependent; cytosol; nucleus; protein binding; chromatin binding;
PPP1CA	6	transforming growth factor beta receptor signaling pathway; cytosol; nucleolus; cytoplasm; nucleus; protein binding;
MED12	6	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MED4	6	transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
RORA	6	transcription initiation from RNA polymerase II promoter; nucleoplasm; protein binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;
TAF10	6	transcription initiation from RNA polymerase II promoter; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
TAF13	6	transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
TAF4B	6	transcription initiation from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; nucleoplasm; gene expression;
AATF	6	response to DNA damage stimulus; nucleolus; cytoplasm; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter;
ALKBH8	6	response to DNA damage stimulus; cytosol; nucleolus; cytoplasm; nucleus; protein binding;
EGLN3	6	response to DNA damage stimulus; cytosol; cytoplasm; nucleus; nucleoplasm; protein binding;
RAD1	6	response to DNA damage stimulus; DNA repair; nucleolus; nucleus; nucleoplasm; protein binding;
RPS3	6	response to DNA damage stimulus; cytosol; cytoplasm; nucleus; protein binding; gene expression;
TRIP12	6	response to DNA damage stimulus; DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding;
CBX3	6	chromatin remodeling; transcription, DNA-dependent; nucleus; protein binding; chromatin; negative regulation of transcription, DNA-dependent;
SMARCD3	6	chromatin remodeling; transcription, DNA-dependent; cytoplasm; nucleus; nucleoplasm; protein binding;
CBFA2T3	6	transcription, DNA-dependent; nucleolus; nucleoplasm; protein binding; chromatin binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA13	6	transcription, DNA-dependent; nucleus; sequence-specific DNA binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of apoptotic process;
IKZF1	6	transcription, DNA-dependent; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
LPIN1	6	transcription, DNA-dependent; cytosol; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
PRKCB	6	transcription, DNA-dependent; cytosol; cytoplasm; nucleus; protein binding; chromatin binding;
PSPC1	6	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding; nuclear matrix;
RNF2	6	transcription, DNA-dependent; nucleolus; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter;
TCF25	6	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
CEP164	6	cytosol; DNA repair; nucleolus; cytoplasm; nucleus; protein binding;
DCPS	6	cytosol; nucleolus; cytoplasm; nucleus; protein binding; gene expression;
FANCC	6	cytosol; DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding;
IARS	6	cytosol; nucleolus; cytoplasm; nucleus; protein binding; gene expression;
MALT1	6	cytosol; nucleolus; cytoplasm; nucleus; protein binding; protein complex;
PAFAH1B1	6	cytosol; nucleolus; cytoplasm; nucleus; protein binding; negative regulation of JNK cascade;
PLK1	6	cytosol; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cyclin-dependent protein kinase activity;
PRKD1	6	cytosol; cytoplasm; nucleus; protein binding; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter;
PSMC3	6	cytosol; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
PYCARD	6	cytosol; cytoplasm; nucleus; protein binding; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;
RFWD2	6	cytosol; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding;
SMG1	6	cytosol; DNA repair; cytoplasm; nucleus; protein binding; gene expression;
SNCA	6	cytosol; cytoplasm; nucleus; protein binding; negative regulation of protein phosphorylation; protein N-terminus binding;
WWOX	6	cytosol; cytoplasm; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of apoptotic process;
FEN1	6	DNA repair; nucleolus; nucleus; nucleoplasm; protein binding; double-stranded DNA binding;
RAD23B	6	DNA repair; nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding;
RBM14	6	DNA repair; nucleolus; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter; protein binding, bridging;
DGCR8	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
DHX9	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
EFTUD2	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
FUS	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
HNRNPA2B1	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
HNRNPH1	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
RCC1	6	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding; chromatin binding;
MAF	6	cytoplasm; nucleus; chromatin; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
FOXC2	6	nucleus; double-stranded DNA binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
FOXE1	6	nucleus; double-stranded DNA binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter;
FOXF1	6	nucleus; double-stranded DNA binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
XPA	5	response to UV; DNA repair; nucleus; nucleoplasm; protein binding;
CDK5RAP2	5	brain development; cytosol; cytoplasm; protein binding; transcription regulatory region DNA binding;
INPPL1	5	brain development; negative regulation of cell proliferation; cytosol; cytoplasm; protein binding;
PTCH1	5	brain development; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of osteoblast differentiation; negative regulation of sequence-specific DNA binding transcription factor activity;
CUL5	5	negative regulation of cell proliferation; cell cycle arrest; cytosol; nucleus; protein binding;
FOSL1	5	negative regulation of cell proliferation; cytosol; nucleus; protein binding; positive regulation of apoptotic process;
KANK2	5	negative regulation of cell proliferation; transcription, DNA-dependent; cytoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
KLF11	5	negative regulation of cell proliferation; nucleus; negative regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; positive regulation of apoptotic process;
NCK2	5	negative regulation of cell proliferation; cytosol; cytoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter;
NUP62	5	negative regulation of cell proliferation; transcription, DNA-dependent; cytoplasm; protein binding; chromatin binding;
PTPN14	5	negative regulation of cell proliferation; transcription, DNA-dependent; cytoplasm; nucleus; protein binding;
PTPRK	5	negative regulation of cell proliferation; transforming growth factor beta receptor signaling pathway; protein binding; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent;
TGFB1I1	5	negative regulation of cell proliferation; cytoplasm; protein binding; nuclear matrix; positive regulation of transforming growth factor beta receptor signaling pathway;
GTF2H3	5	transcription initiation from RNA polymerase II promoter; DNA repair; nucleoplasm; protein N-terminus binding; gene expression;
MAML2	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MED13	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MED14	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MED15	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; gene expression;
MED17	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; gene expression;
MED30	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; gene expression;
NR3C2	5	transcription initiation from RNA polymerase II promoter; nucleoplasm; protein binding; sequence-specific DNA binding; gene expression;
NR4A3	5	transcription initiation from RNA polymerase II promoter; nucleus; nucleoplasm; sequence-specific DNA binding; gene expression;
NR6A1	5	transcription initiation from RNA polymerase II promoter; nucleoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; gene expression;
POLR2G	5	transcription initiation from RNA polymerase II promoter; DNA repair; nucleus; nucleoplasm; gene expression;
THRAP3	5	transcription initiation from RNA polymerase II promoter; nucleolus; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter;
CCND1	5	response to DNA damage stimulus; cytosol; nucleus; nucleoplasm; protein binding;
H2AFX	5	response to DNA damage stimulus; DNA repair; nucleus; nucleoplasm; protein binding;
HERC2	5	response to DNA damage stimulus; DNA repair; cytoplasm; nucleus; protein binding;
BNIP3	5	chromatin remodeling; cytoplasm; nucleus; nucleoplasm; protein binding;
RSF1	5	chromatin remodeling; nucleus; nucleoplasm; protein binding; negative regulation of transcription, DNA-dependent;
ARID3C	5	transcription, DNA-dependent; cytoplasm; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter;
ASF1A	5	transcription, DNA-dependent; DNA repair; nucleus; protein binding; chromatin binding;
ATF6	5	transcription, DNA-dependent; nucleus; nucleoplasm; protein binding; sequence-specific DNA binding;
BCL11A	5	transcription, DNA-dependent; cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; hemopoiesis;
BIRC2	5	transcription, DNA-dependent; cytosol; nucleus; protein binding; protein N-terminus binding;
BRMS1	5	transcription, DNA-dependent; cytoplasm; nucleus; protein binding; negative regulation of transcription, DNA-dependent;
BSX	5	transcription, DNA-dependent; cytoplasm; nucleus; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
CCDC85B	5	transcription, DNA-dependent; cytoplasm; nucleus; protein binding; negative regulation of transcription, DNA-dependent;
CNOT6	5	transcription, DNA-dependent; cytosol; nucleus; protein binding; gene expression;
CREBZF	5	transcription, DNA-dependent; nucleus; protein binding; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
CTNND1	5	transcription, DNA-dependent; cytosol; cytoplasm; nucleus; protein binding;
EED	5	transcription, DNA-dependent; nucleus; protein binding; chromatin binding; negative regulation of transcription, DNA-dependent;
EEF1D	5	transcription, DNA-dependent; cytosol; nucleus; protein binding; gene expression;
ELK3	5	transcription, DNA-dependent; nucleolus; nucleus; protein binding; negative regulation of transcription, DNA-dependent;
FLII	5	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding;
HABP4	5	transcription, DNA-dependent; cytosol; cytoplasm; nucleus; protein binding;
HOXA1	5	transcription, DNA-dependent; nucleus; protein binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HOXA11	5	transcription, DNA-dependent; nucleolus; cytoplasm; sequence-specific DNA binding; protein complex;
HOXA3	5	transcription, DNA-dependent; nucleolus; nucleus; embryonic skeletal system morphogenesis; sequence-specific DNA binding;
HOXA9	5	transcription, DNA-dependent; cytoplasm; nucleus; protein binding; sequence-specific DNA binding;
IGHMBP2	5	transcription, DNA-dependent; DNA repair; cytoplasm; nucleus; protein binding;
INO80E	5	transcription, DNA-dependent; DNA repair; nucleolus; nucleus; protein binding;
MPHOSPH8	5	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; negative regulation of transcription, DNA-dependent;
NRIP1	5	transcription, DNA-dependent; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
PER1	5	transcription, DNA-dependent; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
PRDM1	5	transcription, DNA-dependent; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding;
RQCD1	5	transcription, DNA-dependent; cytosol; nucleus; protein binding; gene expression;
RRP8	5	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding;
SAP18	5	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; protein binding;
SETD1A	5	transcription, DNA-dependent; nucleolus; nucleus; protein binding; histone methyltransferase complex;
TERF2IP	5	transcription, DNA-dependent; cytoplasm; nucleus; nucleoplasm; protein binding;
TFEB	5	transcription, DNA-dependent; cytoplasm; nucleus; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter;
TXN	5	transcription, DNA-dependent; cytosol; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
ZNF24	5	transcription, DNA-dependent; nucleus; protein binding; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
ZNF263	5	transcription, DNA-dependent; nucleolus; cytoplasm; nucleus; negative regulation of transcription, DNA-dependent;
AIP	5	cytosol; nucleolus; cytoplasm; nucleus; protein binding;
BAIAP2	5	cytosol; nucleolus; cytoplasm; nucleus; protein binding;
CEP57	5	cytosol; nucleolus; cytoplasm; nucleus; protein binding;
IRF9	5	cytosol; cytoplasm; nucleus; nucleoplasm; protein binding;
KIF22	5	cytosol; DNA repair; cytoplasm; nucleus; chromatin;
MAPK7	5	cytosol; nucleus; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter;
NCBP1	5	cytosol; nucleus; nucleoplasm; protein binding; gene expression;
NCK1	5	cytosol; cytoplasm; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter;
PAK1	5	cytosol; cytoplasm; protein binding; MAPK cascade; protein complex;
PARK2	5	cytosol; cytoplasm; nucleus; protein binding; negative regulation of protein phosphorylation;
PDE2A	5	cytosol; cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
PPM1F	5	cytosol; protein binding; negative regulation of transcription, DNA-dependent; protein complex; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;
PTTG1	5	cytosol; DNA repair; cytoplasm; nucleus; protein binding;
RPS9	5	cytosol; nucleolus; cytoplasm; protein binding; gene expression;
SMG7	5	cytosol; cytoplasm; nucleus; protein binding; gene expression;
SNRPD1	5	cytosol; nucleus; nucleoplasm; protein binding; gene expression;
SRP19	5	cytosol; nucleolus; cytoplasm; nucleus; gene expression;
STXBP3	5	cytosol; nucleolus; cytoplasm; nucleus; protein binding;
TNFAIP3	5	cytosol; cytoplasm; nucleus; protein binding; negative regulation of cyclin-dependent protein kinase activity;
WWP1	5	cytosol; cytoplasm; nucleus; protein binding; negative regulation of transcription, DNA-dependent;
DDB1	5	DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding;
FANCA	5	DNA repair; cytoplasm; nucleus; nucleoplasm; protein binding;
POLD3	5	DNA repair; nucleolus; nucleus; nucleoplasm; protein binding;
CDCA5	5	nucleolus; cytoplasm; nucleus; protein binding; chromatin binding;
DDX23	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
FOXD4	5	nucleolus; nucleus; double-stranded DNA binding; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
HNRNPA1	5	nucleolus; cytoplasm; nucleus; nucleoplasm; gene expression;
MTA3	5	nucleolus; cytoplasm; nucleus; chromatin binding; sequence-specific DNA binding;
PRPF4	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
RBM4	5	nucleolus; cytoplasm; nucleus; nucleoplasm; protein binding;
RNF20	5	nucleolus; nucleus; protein binding; chromatin binding; positive regulation of histone methylation;
RPS6KA4	5	nucleolus; cytoplasm; nucleus; protein binding; positive regulation of transcription from RNA polymerase II promoter;
SF3A1	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
SF3A3	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
SNRNP200	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
STAP1	5	nucleolus; cytoplasm; nucleus; protein binding; protein complex;
U2AF1	5	nucleolus; nucleus; nucleoplasm; protein binding; gene expression;
CD2BP2	5	cytoplasm; nucleus; nucleoplasm; protein binding; gene expression;
DACT1	5	cytoplasm; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of JNK cascade;
FOXP2	5	cytoplasm; double-stranded DNA binding; chromatin binding; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
ISL1	5	cytoplasm; nucleus; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
UXT	5	cytoplasm; nucleus; protein binding; chromatin binding; negative regulation of transcription from RNA polymerase II promoter;
VEGFA	5	cytoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter;
WNT11	5	cytoplasm; palate development; transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; positive regulation of apoptotic process;
MEIS2	5	nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter;
MLL	5	nucleus; protein binding; transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; histone methyltransferase complex;
PRPF6	5	nucleus; nucleoplasm; protein binding; positive regulation of transcription from RNA polymerase II promoter; gene expression;

Genes shared at least 2 KEGG pathways with MEN1 (count: 0)

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Region: chr11:64570986..64578766 View in gBrowse