ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RAD9A
Previous Symbol	RAD9
Approved Name	RAD9 homolog A (S. pombe)
Previous Name	RAD9 (S. pombe) homolog
Location	11q13.1-q13.2
Position	chr11:67159423-67165883, +
External Links	HGNC: 9827 Entrez Gene: 5883 Ensembl: ENSG00000172613 UCSC: uc001okr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 20)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019901	protein kinase binding	Molecular Function	IPI[12628935]	51
GO:0030896	checkpoint clamp complex	Cellular Component		1
GO:0017124	SH3 domain binding	Molecular Function	IPI[11971963]	22
GO:0019899	enzyme binding	Molecular Function	IPI[15326225]	47
GO:0008408	3'-5' exonuclease activity	Molecular Function	IDA[10713044]	4
GO:0008853	exodeoxyribonuclease III activity	Molecular Function		2
GO:0006281	DNA repair	Biological Process		62
GO:0006974	response to DNA damage stimulus	Biological Process	IDA[9872989]	37
GO:0005737	cytoplasm	Cellular Component		690
GO:0006260	DNA replication	Biological Process		27
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005730	nucleolus	Cellular Component		243
GO:0005515	protein binding	Molecular Function	IPI[19464297]	910
GO:0005634	nucleus	Cellular Component		770
GO:0000076	DNA replication checkpoint	Biological Process	TAS[8943031]	3
GO:0000077	DNA damage checkpoint	Biological Process		7
GO:0000075	cell cycle checkpoint	Biological Process		21
GO:0071479	cellular response to ionizing radiation	Biological Process		4
GO:0043065	positive regulation of apoptotic process	Biological Process		34
GO:0042826	histone deacetylase binding	Molecular Function	IPI[10846170]	10

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAD9A (count: 75)

Gene Symbol	Pathway Count	Pathway List
RAD1	12	3'-5' exonuclease activity; exodeoxyribonuclease III activity; DNA repair; response to DNA damage stimulus; DNA replication; nucleoplasm; nucleolus; protein binding; nucleus; DNA damage checkpoint; cell cycle checkpoint; cellular response to ionizing radiation;
NCOA6	8	enzyme binding; DNA repair; response to DNA damage stimulus; DNA replication; nucleoplasm; nucleolus; protein binding; nucleus;
MRE11A	8	3'-5' exonuclease activity; DNA repair; response to DNA damage stimulus; nucleoplasm; nucleolus; protein binding; nucleus; cell cycle checkpoint;
CHEK1	8	DNA repair; response to DNA damage stimulus; DNA replication; nucleoplasm; protein binding; nucleus; DNA damage checkpoint; cell cycle checkpoint;
MEN1	8	DNA repair; response to DNA damage stimulus; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus; positive regulation of apoptotic process;
H2AFX	7	enzyme binding; DNA repair; response to DNA damage stimulus; nucleoplasm; protein binding; nucleus; DNA damage checkpoint;
HINFP	7	enzyme binding; DNA repair; nucleoplasm; nucleolus; protein binding; nucleus; DNA damage checkpoint;
SMC1A	7	DNA repair; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus; cell cycle checkpoint;
SSRP1	7	DNA repair; cytoplasm; DNA replication; nucleoplasm; nucleolus; protein binding; nucleus;
USP28	7	DNA repair; response to DNA damage stimulus; nucleoplasm; nucleolus; protein binding; nucleus; DNA damage checkpoint;
CDC45	7	cytoplasm; DNA replication; nucleoplasm; protein binding; nucleus; DNA replication checkpoint; cell cycle checkpoint;
APC	6	protein kinase binding; response to DNA damage stimulus; cytoplasm; protein binding; nucleus; positive regulation of apoptotic process;
CABYR	6	protein kinase binding; SH3 domain binding; enzyme binding; cytoplasm; nucleolus; nucleus;
CCND1	6	protein kinase binding; enzyme binding; response to DNA damage stimulus; nucleoplasm; protein binding; nucleus;
PGR	6	enzyme binding; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
ATM	6	DNA repair; response to DNA damage stimulus; nucleoplasm; protein binding; cell cycle checkpoint; positive regulation of apoptotic process;
BARD1	6	DNA repair; response to DNA damage stimulus; cytoplasm; protein binding; nucleus; positive regulation of apoptotic process;
CHD1L	6	DNA repair; response to DNA damage stimulus; cytoplasm; nucleolus; protein binding; nucleus;
DDB1	6	DNA repair; cytoplasm; nucleoplasm; protein binding; nucleus; cell cycle checkpoint;
FEN1	6	DNA repair; DNA replication; nucleoplasm; nucleolus; protein binding; nucleus;
RAD23B	6	DNA repair; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
TP53BP1	6	DNA repair; response to DNA damage stimulus; cytoplasm; nucleoplasm; protein binding; nucleus;
TRIP12	6	DNA repair; response to DNA damage stimulus; cytoplasm; nucleoplasm; protein binding; nucleus;
XRCC5	6	DNA repair; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
MAPK1	6	response to DNA damage stimulus; cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
RFWD2	6	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus; cell cycle checkpoint;
GSK3B	5	protein kinase binding; cytoplasm; nucleolus; protein binding; nucleus;
MAML1	5	protein kinase binding; nucleoplasm; nucleolus; protein binding; nucleus;
PRC1	5	protein kinase binding; cytoplasm; nucleolus; protein binding; nucleus;
RELA	5	protein kinase binding; cytoplasm; nucleoplasm; protein binding; nucleus;
RPS3	5	protein kinase binding; response to DNA damage stimulus; cytoplasm; protein binding; nucleus;
BAIAP2	5	SH3 domain binding; cytoplasm; nucleolus; protein binding; nucleus;
PTTG1	5	SH3 domain binding; DNA repair; cytoplasm; protein binding; nucleus;
DAXX	5	enzyme binding; cytoplasm; nucleolus; protein binding; nucleus;
TAF10	5	enzyme binding; cytoplasm; nucleoplasm; protein binding; nucleus;
WWOX	5	enzyme binding; cytoplasm; protein binding; nucleus; positive regulation of apoptotic process;
CEP164	5	DNA repair; cytoplasm; nucleolus; protein binding; nucleus;
ERCC8	5	DNA repair; response to DNA damage stimulus; nucleoplasm; protein binding; nucleus;
FANCA	5	DNA repair; cytoplasm; nucleoplasm; protein binding; nucleus;
FANCC	5	DNA repair; cytoplasm; nucleoplasm; protein binding; nucleus;
HERC2	5	DNA repair; response to DNA damage stimulus; cytoplasm; protein binding; nucleus;
IGHMBP2	5	DNA repair; cytoplasm; DNA replication; protein binding; nucleus;
INO80E	5	DNA repair; DNA replication; nucleolus; protein binding; nucleus;
MMS19	5	DNA repair; response to DNA damage stimulus; cytoplasm; protein binding; nucleus;
POLD3	5	DNA repair; nucleoplasm; nucleolus; protein binding; nucleus;
POLD4	5	DNA repair; DNA replication; nucleoplasm; protein binding; nucleus;
RBM14	5	DNA repair; DNA replication; nucleolus; protein binding; nucleus;
SMC3	5	DNA repair; cytoplasm; nucleoplasm; protein binding; nucleus;
AATF	5	response to DNA damage stimulus; cytoplasm; nucleolus; protein binding; nucleus;
ALKBH8	5	response to DNA damage stimulus; cytoplasm; nucleolus; protein binding; nucleus;
APBB1	5	response to DNA damage stimulus; cytoplasm; protein binding; nucleus; positive regulation of apoptotic process;
EGLN3	5	response to DNA damage stimulus; cytoplasm; nucleoplasm; protein binding; nucleus;
IRF7	5	response to DNA damage stimulus; cytoplasm; nucleoplasm; protein binding; nucleus;
MAPK3	5	response to DNA damage stimulus; nucleoplasm; nucleolus; protein binding; nucleus;
YAP1	5	response to DNA damage stimulus; cytoplasm; nucleoplasm; protein binding; nucleus;
ATXN1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
BCLAF1	5	cytoplasm; nucleolus; protein binding; nucleus; positive regulation of apoptotic process;
DGCR8	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
DHX9	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
EFTUD2	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
FUS	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
HNRNPA2B1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
HNRNPH1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
NCOR1	5	cytoplasm; nucleoplasm; protein binding; nucleus; histone deacetylase binding;
NOL8	5	cytoplasm; DNA replication; nucleolus; protein binding; nucleus;
NUMA1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
POLA2	5	cytoplasm; DNA replication; nucleoplasm; nucleolus; nucleus;
PSMC3	5	cytoplasm; nucleoplasm; protein binding; nucleus; cell cycle checkpoint;
RBM4	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
RBPJ	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
RCC1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
SART1	5	cytoplasm; nucleoplasm; nucleolus; protein binding; nucleus;
CDT1	5	DNA replication; nucleoplasm; protein binding; nucleus; DNA replication checkpoint;
MED1	5	DNA replication; nucleoplasm; nucleolus; protein binding; nucleus;
NCOR2	5	nucleoplasm; nucleolus; protein binding; nucleus; histone deacetylase binding;

Genes shared at least 2 KEGG pathways with RAD9A (count: 0)

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Region: chr11:67159423..67165883 View in gBrowse