ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SART1
Symbol Alias	Ara1, Snu66, SNRNP110
Approved Name	squamous cell carcinoma antigen recognized by T cells
Previous Name	squamous cell carcinoma antigen recognised by T cells
Name Alias	small nuclear ribonucleoprotein 110kDa (U4/U6.U5)
Location	11q13.1
Position	chr11:65729160-65747607, +
External Links	HGNC: 10538 Entrez Gene: 9092 Ensembl: ENSG00000175467 UCSC: uc001ogl.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[17000644]	910
GO:0005634	nucleus	Cellular Component		770
GO:0005654	nucleoplasm	Cellular Component	IDA[16687569]	183
GO:0005730	nucleolus	Cellular Component		243
GO:0000387	spliceosomal snRNP assembly	Biological Process	TAS[16687569]	10
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[11991638]	54
GO:0003674	molecular_function	Molecular Function		126
GO:0007050	cell cycle arrest	Biological Process	NAS[16158934]	25
GO:0005829	cytosol	Cellular Component	TAS[10929426]	447
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0005737	cytoplasm	Cellular Component	TAS[9856836]	690
GO:0097193	intrinsic apoptotic signaling pathway	Biological Process	NAS[16158934]	6
GO:0071013	catalytic step 2 spliceosome	Cellular Component	IDA[11991638]	31
GO:0045585	positive regulation of cytotoxic T cell differentiation	Biological Process	IDA[10209962]	1
GO:0015030	Cajal body	Cellular Component	IDA[16687569]	11

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with SART1 (count: 85)

Gene Symbol	Pathway Count	Pathway List
EFTUD2	8	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome; Cajal body;
HNRNPA2B1	7	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome;
HNRNPH1	7	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome;
MAPK1	7	protein binding; nucleus; nucleoplasm; nucleolus; cytosol; Golgi apparatus; cytoplasm;
MEN1	7	protein binding; nucleus; nucleoplasm; nucleolus; cell cycle arrest; cytosol; cytoplasm;
SNRPD1	7	protein binding; nucleus; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;
U2AF1	7	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; Cajal body;
CEP57	6	protein binding; nucleus; nucleolus; cytosol; Golgi apparatus; cytoplasm;
COG5	6	protein binding; nucleus; nucleolus; molecular_function; cytosol; Golgi apparatus;
DDX23	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
DHX9	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm;
FUS	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm;
MAPK3	6	protein binding; nucleus; nucleoplasm; nucleolus; cytosol; Golgi apparatus;
NCBP1	6	protein binding; nucleus; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol;
NUMA1	6	protein binding; nucleus; nucleoplasm; nucleolus; cytosol; cytoplasm;
PRPF4	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; Cajal body;
RFWD2	6	protein binding; nucleus; nucleoplasm; nucleolus; cytosol; cytoplasm;
SF3A1	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SF3A3	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SMC1A	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm;
SNRNP200	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SNRPB	6	protein binding; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;
SNRPD2	6	protein binding; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;
SNRPD3	6	protein binding; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;
SNRPG	6	protein binding; nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;
SNW1	6	protein binding; nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
XPO1	6	protein binding; nucleoplasm; nucleolus; cytosol; cytoplasm; Cajal body;
HNRNPA1	6	nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome;
AATF	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
AIP	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
ALKBH8	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
APC	5	protein binding; nucleus; cell cycle arrest; cytosol; cytoplasm;
ATXN1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
ATXN2	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
BAIAP2	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
BNIP3	5	protein binding; nucleus; nucleoplasm; cytoplasm; intrinsic apoptotic signaling pathway;
CD2BP2	5	protein binding; nucleus; nucleoplasm; mRNA splicing, via spliceosome; cytoplasm;
CEP164	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
COG3	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
CRYAB	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
CUL5	5	protein binding; nucleus; cell cycle arrest; cytosol; intrinsic apoptotic signaling pathway;
DAXX	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
DCPS	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
DGCR8	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
DHX8	5	protein binding; nucleus; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
EGLN3	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
FANCC	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
GSK3B	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
HINFP	5	protein binding; nucleus; nucleoplasm; nucleolus; Cajal body;
IARS	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
ID2	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
IRF7	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
IRF9	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
KLHL20	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
MALT1	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
NEDD4L	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
PAFAH1B1	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
PARK2	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
PDCD4	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
PDE2A	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
PGR	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
PPP1CA	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
PRKD1	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
PRPF19	5	protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome;
PRPF6	5	protein binding; nucleus; nucleoplasm; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
PSMC3	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
RAD23B	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RAD9A	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RBM4	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RBPJ	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RCC1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
RELA	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
SNCA	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
SSRP1	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
STRN3	5	protein binding; nucleus; nucleoplasm; Golgi apparatus; cytoplasm;
STXBP3	5	protein binding; nucleus; nucleolus; cytosol; cytoplasm;
TFAP2A	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
TRIM5	5	protein binding; nucleus; nucleolus; Golgi apparatus; cytoplasm;
WWOX	5	protein binding; nucleus; cytosol; Golgi apparatus; cytoplasm;
XRCC5	5	protein binding; nucleus; nucleoplasm; nucleolus; cytoplasm;
YAP1	5	protein binding; nucleus; nucleoplasm; cytosol; cytoplasm;
POLA2	5	nucleus; nucleoplasm; nucleolus; molecular_function; cytoplasm;
SF3B2	5	nucleus; nucleoplasm; nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SLU7	5	nucleus; nucleolus; mRNA splicing, via spliceosome; cytoplasm; catalytic step 2 spliceosome;
SNRPF	5	nucleoplasm; spliceosomal snRNP assembly; mRNA splicing, via spliceosome; cytosol; catalytic step 2 spliceosome;

Genes shared at least 2 KEGG pathways with SART1 (count: 0)

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Region: chr11:65729160..65747607 View in gBrowse