ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	AIP
Symbol Alias	XAP2, ARA9, FKBP16
Approved Name	aryl hydrocarbon receptor interacting protein
Previous Name	aryl hydrocarbon receptor-interacting protein
Location	11q13.3
Position	chr11:67250505-67258579, +
External Links	HGNC: 358 Entrez Gene: 9049 Ensembl: ENSG00000110711 UCSC: uc001olv.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004871	signal transducer activity	Molecular Function	TAS[9111057]	49
GO:0003713	transcription coactivator activity	Molecular Function	TAS[9447995]	52
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910
GO:0005737	cytoplasm	Cellular Component		690
GO:0005730	nucleolus	Cellular Component		243
GO:0005886	plasma membrane	Cellular Component	IDA[17329248]	772
GO:0005829	cytosol	Cellular Component	IDA[17329248]; TAS[14557246]	447
GO:0006805	xenobiotic metabolic process	Biological Process		25
GO:0006626	protein targeting to mitochondrion	Biological Process	IDA[14557246]	7
GO:0008134	transcription factor binding	Molecular Function	TAS[9447995]	38
GO:0007165	signal transduction	Biological Process	TAS[9111057]	171
GO:0010738	regulation of protein kinase A signaling cascade	Biological Process		2
GO:0022417	protein maturation by protein folding	Biological Process	IDA[14557246]	1
GO:0036004	GAF domain binding	Molecular Function	IDA[17329248]	1
GO:0044445	cytosolic part	Cellular Component		3
GO:0051082	unfolded protein binding	Molecular Function	IDA[14557246]	19
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	Biological Process		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AIP (count: 71)

Gene Symbol	Pathway Count	Pathway List
MALT1	7	signal transducer activity; nucleus; protein binding; cytoplasm; nucleolus; plasma membrane; cytosol;
MAPK1	7	nucleus; protein binding; cytoplasm; nucleolus; cytosol; transcription factor binding; signal transduction;
CBL	6	signal transducer activity; nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
APBB1	6	nucleus; protein binding; cytoplasm; plasma membrane; transcription factor binding; signal transduction;
ARRB1	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; transcription factor binding;
BAIAP2	6	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane; cytosol;
CRYAB	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; unfolded protein binding;
DAXX	6	nucleus; protein binding; cytoplasm; nucleolus; cytosol; transcription factor binding;
GSK3B	6	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane; cytosol;
HSPA8	6	nucleus; protein binding; nucleolus; plasma membrane; cytosol; unfolded protein binding;
PDE2A	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; protein targeting to mitochondrion;
PRKCB	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; signal transduction;
PRKD1	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; signal transduction;
STXBP3	6	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane; cytosol;
WWP1	6	nucleus; protein binding; cytoplasm; plasma membrane; cytosol; signal transduction;
BCAR1	5	signal transducer activity; protein binding; cytoplasm; plasma membrane; cytosol;
CLOCK	5	signal transducer activity; nucleus; nucleolus; cytosol; signal transduction;
EEF1D	5	signal transducer activity; nucleus; protein binding; cytosol; signal transduction;
IKBKAP	5	signal transducer activity; protein binding; cytoplasm; nucleolus; signal transduction;
ILK	5	signal transducer activity; protein binding; cytoplasm; plasma membrane; cytosol;
MAGI2	5	signal transducer activity; nucleus; protein binding; cytoplasm; plasma membrane;
NEK6	5	signal transducer activity; nucleus; protein binding; cytoplasm; signal transduction;
KAT5	5	transcription coactivator activity; nucleus; protein binding; nucleolus; cytosol;
MED1	5	transcription coactivator activity; nucleus; protein binding; nucleolus; transcription factor binding;
PSMC3	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; cytosol;
RAN	5	transcription coactivator activity; protein binding; cytoplasm; cytosol; signal transduction;
RIPK3	5	transcription coactivator activity; protein binding; plasma membrane; cytosol; signal transduction;
SMARCD3	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; transcription factor binding;
TFAP2A	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; nucleolus;
UBE3A	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; cytosol;
YAP1	5	transcription coactivator activity; nucleus; protein binding; cytoplasm; cytosol;
AKAP7	5	nucleus; protein binding; plasma membrane; cytosol; regulation of protein kinase A signaling cascade;
ALKBH8	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
APC	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
ARRB2	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
CDCA5	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
CEP164	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
CEP57	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
CHD1L	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
COG3	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
CTNND1	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
DCPS	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
GSTP1	5	nucleus; protein binding; cytoplasm; cytosol; xenobiotic metabolic process;
IARS	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
ID2	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
LPXN	5	nucleus; protein binding; cytoplasm; plasma membrane; signal transduction;
MEN1	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
NCK1	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
NF2	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
NUMA1	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
PAFAH1B1	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
PDCD4	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
PGR	5	nucleus; protein binding; cytoplasm; nucleolus; signal transduction;
PPP1CA	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
PRC1	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
PYCARD	5	nucleus; protein binding; cytoplasm; cytosol; signal transduction;
RELA	5	nucleus; protein binding; cytoplasm; cytosol; transcription factor binding;
RFWD2	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
RILPL1	5	nucleus; cytoplasm; nucleolus; plasma membrane; cytosol;
RNF40	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
RRP8	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
SAP18	5	nucleus; protein binding; cytoplasm; nucleolus; plasma membrane;
SART1	5	nucleus; protein binding; cytoplasm; nucleolus; cytosol;
SERGEF	5	nucleus; protein binding; cytoplasm; nucleolus; signal transduction;
SNCA	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
STAP1	5	nucleus; protein binding; cytoplasm; nucleolus; signal transduction;
TJP1	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
WWOX	5	nucleus; protein binding; cytoplasm; plasma membrane; cytosol;
ADRBK1	5	protein binding; cytoplasm; plasma membrane; cytosol; signal transduction;
MAPK9	5	protein binding; cytosol; protein targeting to mitochondrion; transcription factor binding; cytosolic part;
PRKG1	5	protein binding; cytoplasm; plasma membrane; cytosol; signal transduction;

Genes shared at least 2 KEGG pathways with AIP (count: 0)

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Region: chr11:67250505..67258579 View in gBrowse