ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	AIP
Symbol Alias	XAP2, ARA9, FKBP16
Approved Name	aryl hydrocarbon receptor interacting protein
Previous Name	"aryl hydrocarbon receptor-interacting protein"
Location	11q13.3
Position	chr11:67250512-67258574, 1
External Links	HGNC: 358 Entrez Gene: 9049 Ensembl: ENSG00000110711 UCSC: uc001olv.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	cellular component	IDA	781
GO:0051082	unfolded protein binding	molecular function	IDA[14557246]	23
GO:0007165	signal transduction	biological process	TAS[9111057]	189
GO:0044445	cytosolic part	cellular component	IEA	3
GO:0006626	protein targeting to mitochondrion	biological process	IDA[14557246]	10
GO:0005886	plasma membrane	cellular component	IDA[17329248]	839
GO:0005730	nucleolus	cellular component	IDA	271
GO:0005515	protein binding	molecular function	IPI	1015
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	biological process	IEA	1
GO:0008134	transcription factor binding	molecular function	TAS[9447995]	44
GO:0005829	cytosol	cellular component	IDA[17329248]; TAS[14557246]	485
GO:0010738	regulation of protein kinase A signaling cascade	biological process	IEA	2
GO:0005634	nucleus	cellular component	IDA	877
GO:0006805	xenobiotic metabolic process	biological process	IEA	26
GO:0004871	signal transducer activity	molecular function	TAS[9111057]	56
GO:0036004	GAF domain binding	molecular function	IDA[17329248]	1
GO:0003713	transcription coactivator activity	molecular function	TAS[9447995]	58
GO:0022417	protein maturation by protein folding	biological process	IDA[14557246]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AIP (count: 74)

Gene Symbol	Pathway Count	Pathway List
MALT1	7	cytoplasm; plasma membrane; nucleolus; protein binding; cytosol; nucleus; signal transducer activity;
CREBBP	7	cytoplasm; signal transduction; protein binding; transcription factor binding; nucleus; signal transducer activity; transcription coactivator activity;
MAPK1	7	cytoplasm; signal transduction; nucleolus; protein binding; transcription factor binding; cytosol; nucleus;
CBL	6	cytoplasm; plasma membrane; protein binding; cytosol; nucleus; signal transducer activity;
PRKD1	6	cytoplasm; signal transduction; plasma membrane; protein binding; cytosol; nucleus;
CRYAB	6	cytoplasm; unfolded protein binding; plasma membrane; protein binding; cytosol; nucleus;
DAXX	6	cytoplasm; nucleolus; protein binding; transcription factor binding; cytosol; nucleus;
ARRB1	6	cytoplasm; plasma membrane; protein binding; transcription factor binding; cytosol; nucleus;
BAIAP2	6	cytoplasm; plasma membrane; nucleolus; protein binding; cytosol; nucleus;
GSK3B	6	cytoplasm; plasma membrane; nucleolus; protein binding; cytosol; nucleus;
STXBP3	6	cytoplasm; plasma membrane; nucleolus; protein binding; cytosol; nucleus;
PDE2A	6	cytoplasm; protein targeting to mitochondrion; plasma membrane; protein binding; cytosol; nucleus;
DNAJA3	6	cytoplasm; unfolded protein binding; protein binding; transcription factor binding; cytosol; nucleus;
AXIN1	6	cytoplasm; plasma membrane; protein binding; cytosol; nucleus; signal transducer activity;
APBB1	6	cytoplasm; signal transduction; plasma membrane; protein binding; transcription factor binding; nucleus;
HSPA8	6	unfolded protein binding; plasma membrane; nucleolus; protein binding; cytosol; nucleus;
PARN	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
NF2	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
TJP1	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
SNCA	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
RRP8	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
ADRBK1	5	cytoplasm; signal transduction; plasma membrane; protein binding; cytosol;
IKBKAP	5	cytoplasm; signal transduction; nucleolus; protein binding; signal transducer activity;
SART1	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
DCPS	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
PRKG1	5	cytoplasm; signal transduction; plasma membrane; protein binding; cytosol;
MGRN1	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
LPXN	5	cytoplasm; signal transduction; plasma membrane; protein binding; nucleus;
RELA	5	cytoplasm; protein binding; transcription factor binding; cytosol; nucleus;
GSTP1	5	cytoplasm; protein binding; cytosol; nucleus; xenobiotic metabolic process;
CHD1L	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
ARRB2	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
HMGCS1	5	cytoplasm; plasma membrane; nucleolus; cytosol; nucleus;
NCK1	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
ALKBH8	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
YAP1	5	cytoplasm; protein binding; cytosol; nucleus; transcription coactivator activity;
SMARCD3	5	cytoplasm; protein binding; transcription factor binding; nucleus; transcription coactivator activity;
UBE3A	5	cytoplasm; protein binding; cytosol; nucleus; transcription coactivator activity;
PAFAH1B1	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
PYCARD	5	cytoplasm; signal transduction; protein binding; cytosol; nucleus;
IARS	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
PRC1	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
MEN1	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
PPP1CA	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
MAGI2	5	cytoplasm; plasma membrane; protein binding; nucleus; signal transducer activity;
APC	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
NEK6	5	cytoplasm; signal transduction; protein binding; nucleus; signal transducer activity;
STAP1	5	cytoplasm; signal transduction; nucleolus; protein binding; nucleus;
CEP164	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
ID2	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
ILK	5	cytoplasm; plasma membrane; protein binding; cytosol; signal transducer activity;
PDCD4	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
WWOX	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
BCAR1	5	cytoplasm; plasma membrane; protein binding; cytosol; signal transducer activity;
RILPL1	5	cytoplasm; plasma membrane; nucleolus; cytosol; nucleus;
CEP57	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
RAN	5	cytoplasm; signal transduction; protein binding; cytosol; transcription coactivator activity;
RNF40	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
CDCA5	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
NUMA1	5	cytoplasm; nucleolus; protein binding; cytosol; nucleus;
CTNND1	5	cytoplasm; plasma membrane; protein binding; cytosol; nucleus;
PSMC3	5	cytoplasm; protein binding; cytosol; nucleus; transcription coactivator activity;
PGR	5	cytoplasm; signal transduction; nucleolus; protein binding; nucleus;
SERGEF	5	cytoplasm; signal transduction; nucleolus; protein binding; nucleus;
SAP18	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
COG3	5	cytoplasm; plasma membrane; nucleolus; protein binding; nucleus;
CLOCK	5	signal transduction; nucleolus; cytosol; nucleus; signal transducer activity;
TLE1	5	signal transduction; protein binding; transcription factor binding; cytosol; nucleus;
EEF1D	5	signal transduction; protein binding; cytosol; nucleus; signal transducer activity;
RIPK3	5	signal transduction; plasma membrane; protein binding; cytosol; transcription coactivator activity;
MAPK9	5	cytosolic part; protein targeting to mitochondrion; protein binding; transcription factor binding; cytosol;
AKAP7	5	plasma membrane; protein binding; cytosol; regulation of protein kinase A signaling cascade; nucleus;
KAT5	5	nucleolus; protein binding; cytosol; nucleus; transcription coactivator activity;
MED1	5	nucleolus; protein binding; transcription factor binding; nucleus; transcription coactivator activity;

Genes shared at least 2 KEGG pathways with AIP (count: 0)

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Region: chr11:67250512..67258574 View in gBrowse