Gene Symbol |
Pathway Count |
Pathway List |
GSK3B |
13 |
ATP binding;
integrin binding;
neuronal cell body;
dendritic shaft;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
positive regulation of cell-matrix adhesion;
peptidyl-serine phosphorylation;
cytoplasm;
protein kinase binding;
cytosol;
plasma membrane;
|
PAK1 |
12 |
neuron projection morphogenesis;
ATP binding;
cell-cell junction;
focal adhesion;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
protein kinase binding;
protein complex;
cytosol;
plasma membrane;
|
MAPK1 |
11 |
positive regulation of cell migration;
ATP binding;
focal adhesion;
protein serine/threonine kinase activity;
protein binding;
positive regulation of transcription, DNA-dependent;
positive regulation of cell proliferation;
peptidyl-serine phosphorylation;
cytoplasm;
protein complex;
cytosol;
|
BCAR1 |
11 |
positive regulation of cell migration;
integrin-mediated signaling pathway;
focal adhesion;
signal transducer activity;
SH3 domain binding;
protein binding;
cell proliferation;
cytoplasm;
protein kinase binding;
cytosol;
plasma membrane;
|
PRKD1 |
11 |
ATP binding;
cell-cell junction;
integrin-mediated signaling pathway;
protein serine/threonine kinase activity;
protein binding;
cell proliferation;
positive regulation of osteoblast differentiation;
peptidyl-serine phosphorylation;
cytoplasm;
cytosol;
plasma membrane;
|
PDPK1 |
11 |
ATP binding;
negative regulation of cardiac muscle cell apoptotic process;
focal adhesion;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
negative regulation of protein kinase activity;
cytoplasm;
protein kinase binding;
cytosol;
plasma membrane;
|
TGFBR1 |
10 |
positive regulation of protein kinase B signaling cascade;
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
positive regulation of transcription, DNA-dependent;
positive regulation of cell proliferation;
peptidyl-serine phosphorylation;
cell cycle arrest;
plasma membrane;
|
ADAM17 |
9 |
positive regulation of cell migration;
cell-cell junction;
integrin binding;
focal adhesion;
SH3 domain binding;
protein binding;
positive regulation of cell proliferation;
cytoplasm;
plasma membrane;
|
STK11 |
9 |
ATP binding;
protein heterooligomerization;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cell cycle arrest;
cytoplasm;
protein complex;
cytosol;
|
SYK |
9 |
ATP binding;
integrin-mediated signaling pathway;
integrin binding;
protein phosphorylation;
protein binding;
cell proliferation;
protein kinase binding;
cytosol;
plasma membrane;
|
TSC1 |
8 |
cell-matrix adhesion;
protein heterooligomerization;
protein binding;
cell cycle arrest;
lamellipodium;
cytoplasm;
protein complex;
cytosol;
|
PIK3CG |
8 |
positive regulation of protein kinase B signaling cascade;
ATP binding;
protein serine/threonine kinase activity;
protein binding;
positive regulation of MAP kinase activity;
cytoplasm;
cytosol;
plasma membrane;
|
APC |
8 |
positive regulation of cell migration;
protein binding;
cell cycle arrest;
lamellipodium;
cytoplasm;
protein kinase binding;
cytosol;
plasma membrane;
|
PLK1 |
8 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cell proliferation;
peptidyl-serine phosphorylation;
protein kinase binding;
cytosol;
|
NEK6 |
8 |
ATP binding;
protein serine/threonine kinase activity;
signal transducer activity;
protein phosphorylation;
protein binding;
peptidyl-serine phosphorylation;
cytoplasm;
protein kinase binding;
|
DNAJA3 |
7 |
cell aging;
ATP binding;
protein binding;
negative regulation of protein kinase activity;
cytoplasm;
protein kinase binding;
cytosol;
|
SNCA |
7 |
terminal bouton;
extracellular fibril organization;
protein binding;
negative regulation of neuron apoptotic process;
cytoplasm;
cytosol;
plasma membrane;
|
ADRA2A |
7 |
positive regulation of cell migration;
protein binding;
positive regulation of MAP kinase activity;
positive regulation of cell proliferation;
cytoplasm;
protein kinase binding;
plasma membrane;
|
ROCK2 |
7 |
ATP binding;
regulation of actin cytoskeleton organization;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytosol;
plasma membrane;
|
PRKAA1 |
7 |
ATP binding;
protein heterooligomerization;
protein phosphorylation;
protein binding;
positive regulation of cell proliferation;
cell cycle arrest;
cytosol;
|
CTNND1 |
7 |
cell-cell junction;
protein binding;
cell junction assembly;
lamellipodium;
cytoplasm;
cytosol;
plasma membrane;
|
TSC2 |
7 |
neuronal cell body;
protein heterooligomerization;
protein binding;
cell cycle arrest;
negative regulation of protein kinase activity;
cytoplasm;
cytosol;
|
AXIN1 |
7 |
signal transducer activity;
protein binding;
positive regulation of transcription, DNA-dependent;
cytoplasm;
protein kinase binding;
cytosol;
plasma membrane;
|
ADORA2A |
6 |
neuron projection morphogenesis;
neuronal cell body;
protein binding;
negative regulation of neuron apoptotic process;
negative regulation of protein kinase activity;
plasma membrane;
|
MIF |
6 |
cell aging;
positive regulation of phosphorylation;
protein binding;
cell proliferation;
positive regulation of MAP kinase activity;
cytoplasm;
|
CTGF |
6 |
cell-matrix adhesion;
integrin-mediated signaling pathway;
integrin binding;
positive regulation of cell proliferation;
cytosol;
plasma membrane;
|
PKD1 |
6 |
cell-matrix adhesion;
protein binding;
peptidyl-serine phosphorylation;
cell cycle arrest;
cytoplasm;
protein kinase binding;
|
NTRK2 |
6 |
terminal bouton;
ATP binding;
neuronal cell body;
positive regulation of cell proliferation;
negative regulation of neuron apoptotic process;
cytosol;
|
CORO1A |
6 |
positive regulation of cell migration;
protein binding;
lamellipodium;
cytoplasm;
protein complex;
plasma membrane;
|
LATS1 |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
protein kinase binding;
cytosol;
|
FES |
6 |
ATP binding;
focal adhesion;
protein phosphorylation;
cell proliferation;
cytoplasm;
cytosol;
|
BMPR1B |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
positive regulation of osteoblast differentiation;
plasma membrane;
|
MYO10 |
6 |
ATP binding;
neuronal cell body;
lamellipodium;
cytoplasm;
cytosol;
plasma membrane;
|
RIPK3 |
6 |
ATP binding;
protein heterooligomerization;
protein serine/threonine kinase activity;
protein binding;
cytosol;
plasma membrane;
|
PRKG1 |
6 |
ATP binding;
protein phosphorylation;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
ADRBK1 |
6 |
ATP binding;
protein binding;
peptidyl-serine phosphorylation;
cytoplasm;
cytosol;
plasma membrane;
|
MAP2K3 |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein binding;
positive regulation of transcription, DNA-dependent;
protein kinase binding;
cytosol;
|
SMG1 |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein binding;
peptidyl-serine phosphorylation;
cytoplasm;
cytosol;
|
MARK2 |
6 |
ATP binding;
establishment or maintenance of epithelial cell apical/basal polarity;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
plasma membrane;
|
ERBB2 |
6 |
ATP binding;
protein phosphorylation;
protein binding;
cell proliferation;
positive regulation of MAP kinase activity;
plasma membrane;
|
CSNK1E |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
positive regulation of canonical Wnt receptor signaling pathway;
cytosol;
|
CAMK2D |
6 |
ATP binding;
neuronal cell body;
protein phosphorylation;
peptidyl-serine phosphorylation;
cytosol;
plasma membrane;
|
MAP3K11 |
6 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cell proliferation;
cytoplasm;
|
FZD4 |
6 |
cell-cell junction;
protein binding;
positive regulation of transcription, DNA-dependent;
cytoplasm;
substrate adhesion-dependent cell spreading;
plasma membrane;
|
THY1 |
6 |
integrin binding;
protein binding;
negative regulation of protein kinase activity;
protein kinase binding;
cytosol;
plasma membrane;
|
DIXDC1 |
6 |
focal adhesion;
neuronal cell body;
signal transducer activity;
protein binding;
positive regulation of canonical Wnt receptor signaling pathway;
cytosol;
|
BAIAP2 |
6 |
regulation of actin cytoskeleton organization;
SH3 domain binding;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
CBL |
6 |
signal transducer activity;
SH3 domain binding;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
MALT1 |
6 |
signal transducer activity;
protein binding;
cytoplasm;
protein complex;
cytosol;
plasma membrane;
|
MAPT |
6 |
SH3 domain binding;
protein binding;
positive regulation of axon extension;
protein kinase binding;
cytosol;
plasma membrane;
|
INPPL1 |
6 |
SH3 domain binding;
protein binding;
lamellipodium;
cytoplasm;
cytosol;
plasma membrane;
|
RELA |
6 |
protein binding;
positive regulation of transcription, DNA-dependent;
positive regulation of cell proliferation;
cytoplasm;
protein kinase binding;
cytosol;
|
APBB1 |
6 |
protein binding;
positive regulation of transcription, DNA-dependent;
cell cycle arrest;
lamellipodium;
cytoplasm;
plasma membrane;
|
FLNC |
6 |
protein binding;
cell junction assembly;
costamere;
cytoplasm;
cytosol;
plasma membrane;
|
YAP1 |
6 |
protein binding;
cell proliferation;
positive regulation of cell proliferation;
positive regulation of canonical Wnt receptor signaling pathway;
cytoplasm;
cytosol;
|
MEN1 |
6 |
protein binding;
positive regulation of osteoblast differentiation;
cell cycle arrest;
cytoplasm;
protein complex;
cytosol;
|
GJA1 |
5 |
neuron projection morphogenesis;
signal transducer activity;
SH3 domain binding;
protein binding;
plasma membrane;
|
ITGA1 |
5 |
cell-matrix adhesion;
integrin-mediated signaling pathway;
integrin binding;
protein binding;
plasma membrane;
|
IL6 |
5 |
positive regulation of protein kinase B signaling cascade;
positive regulation of osteoblast differentiation;
positive regulation of transcription, DNA-dependent;
positive regulation of cell proliferation;
negative regulation of protein kinase activity;
|
ARRB2 |
5 |
positive regulation of protein kinase B signaling cascade;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
PTPRJ |
5 |
positive regulation of protein kinase B signaling cascade;
cell-cell junction;
protein binding;
protein kinase binding;
plasma membrane;
|
ADAM8 |
5 |
positive regulation of protein kinase B signaling cascade;
protein binding;
negative regulation of neuron apoptotic process;
cytoplasm;
plasma membrane;
|
DRD4 |
5 |
terminal bouton;
neuronal cell body;
SH3 domain binding;
protein binding;
plasma membrane;
|
TRPC1 |
5 |
sarcomere;
protein binding;
costamere;
protein complex;
plasma membrane;
|
GRB10 |
5 |
positive regulation of phosphorylation;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
PIK3R1 |
5 |
positive regulation of cell migration;
protein phosphorylation;
protein binding;
cytosol;
plasma membrane;
|
WNT11 |
5 |
positive regulation of cell migration;
protein phosphorylation;
positive regulation of transcription, DNA-dependent;
cytoplasm;
plasma membrane;
|
DAB2 |
5 |
positive regulation of cell migration;
integrin binding;
protein binding;
cell proliferation;
positive regulation of transcription, DNA-dependent;
|
ROR2 |
5 |
positive regulation of cell migration;
ATP binding;
protein binding;
positive regulation of transcription, DNA-dependent;
positive regulation of canonical Wnt receptor signaling pathway;
|
IKBKAP |
5 |
positive regulation of cell migration;
signal transducer activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
CDH13 |
5 |
positive regulation of cell migration;
positive regulation of cell-matrix adhesion;
cell junction assembly;
cytoplasm;
plasma membrane;
|
VEGFA |
5 |
positive regulation of cell migration;
protein binding;
positive regulation of MAP kinase activity;
positive regulation of cell proliferation;
cytoplasm;
|
LATS2 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytosol;
|
SIK3 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
TWF2 |
5 |
ATP binding;
regulation of actin cytoskeleton organization;
lamellipodium;
cytoplasm;
positive regulation of axon extension;
|
FLT4 |
5 |
ATP binding;
protein binding;
positive regulation of cell proliferation;
cytoplasm;
plasma membrane;
|
CDC42BPG |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
PRKAG2 |
5 |
ATP binding;
cell cycle arrest;
negative regulation of protein kinase activity;
protein kinase binding;
cytosol;
|
ATM |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein binding;
peptidyl-serine phosphorylation;
cell cycle arrest;
|
NUBP1 |
5 |
ATP binding;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
GAK |
5 |
ATP binding;
focal adhesion;
protein serine/threonine kinase activity;
protein binding;
cytoplasm;
|
RPS6KA4 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
FRK |
5 |
ATP binding;
protein phosphorylation;
protein binding;
cytoplasm;
plasma membrane;
|
STK36 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
TNNI3K |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
SIK2 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
TSSK2 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
protein binding;
cytoplasm;
|
WNK2 |
5 |
ATP binding;
protein serine/threonine kinase activity;
protein phosphorylation;
cytoplasm;
plasma membrane;
|
MAPK3 |
5 |
ATP binding;
focal adhesion;
protein phosphorylation;
protein binding;
cytosol;
|
RDX |
5 |
focal adhesion;
protein binding;
lamellipodium;
cytoplasm;
plasma membrane;
|
CACNA1C |
5 |
neuronal cell body;
dendritic shaft;
protein binding;
cytoplasm;
plasma membrane;
|
STRN3 |
5 |
neuronal cell body;
protein binding;
cytoplasm;
protein complex;
plasma membrane;
|
PAFAH1B1 |
5 |
neuronal cell body;
protein binding;
cytoplasm;
positive regulation of axon extension;
cytosol;
|
MAGI2 |
5 |
protein heterooligomerization;
signal transducer activity;
protein binding;
cytoplasm;
plasma membrane;
|
SQSTM1 |
5 |
protein heterooligomerization;
protein serine/threonine kinase activity;
protein binding;
protein kinase binding;
cytosol;
|
STXBP3 |
5 |
protein heterooligomerization;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
HTR2A |
5 |
dendritic shaft;
positive regulation of MAP kinase activity;
positive regulation of cell proliferation;
cytosol;
plasma membrane;
|
AIP |
5 |
signal transducer activity;
protein binding;
cytoplasm;
cytosol;
plasma membrane;
|
IRF7 |
5 |
protein phosphorylation;
protein binding;
positive regulation of transcription, DNA-dependent;
cytoplasm;
cytosol;
|
ID2 |
5 |
protein binding;
positive regulation of transcription, DNA-dependent;
cytoplasm;
protein complex;
cytosol;
|
GAB2 |
5 |
protein binding;
positive regulation of cell proliferation;
cytoplasm;
cytosol;
plasma membrane;
|
CUL5 |
5 |
protein binding;
cell proliferation;
cell cycle arrest;
cytosol;
plasma membrane;
|
PARK2 |
5 |
protein binding;
negative regulation of neuron apoptotic process;
cytoplasm;
protein kinase binding;
cytosol;
|
PLCE1 |
5 |
protein binding;
cell proliferation;
cytoplasm;
cytosol;
plasma membrane;
|
NF2 |
5 |
protein binding;
negative regulation of protein kinase activity;
lamellipodium;
cytoplasm;
plasma membrane;
|
GOLPH3 |
5 |
protein binding;
cell proliferation;
cytoplasm;
cytosol;
plasma membrane;
|
CDK5RAP2 |
5 |
protein binding;
positive regulation of transcription, DNA-dependent;
cytoplasm;
protein kinase binding;
cytosol;
|
AKAP7 |
5 |
protein binding;
protein kinase binding;
protein complex;
cytosol;
plasma membrane;
|
RPTOR |
5 |
protein binding;
cell cycle arrest;
cytoplasm;
protein kinase binding;
cytosol;
|
SOCS1 |
5 |
protein binding;
negative regulation of protein kinase activity;
cytoplasm;
protein kinase binding;
cytosol;
|
PDCD10 |
5 |
protein binding;
positive regulation of MAP kinase activity;
positive regulation of cell proliferation;
cytosol;
plasma membrane;
|