ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0017124
Name SH3 domain binding
Type molecular function
No. of Genes in ADHDgene  22
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 22)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) IEA
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IDA[9843378]
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3p24.3 1(0/0/1) IEA

Genes from other sources Help (count: 19)

Approved Symbol Approved Name Source Evidence[PMID]
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region IPI[11971963]
ILK integrin-linked kinase Mapped by CNV IEA
GJA1 gap junction protein, alpha 1, 43kDa Mapped by Literature SNP; Mapped by significant region IEA
ARHGAP42 Rho GTPase activating protein 42 Mapped by significant region IEA
FMN1 formin 1 Mapped by CNV; Mapped by significant region IEA
CD3E CD3e molecule, epsilon (CD3-TCR complex) Mapped by significant region IPI[12110186]
DENND1A DENN/MADD domain containing 1A Mapped by significant region IEA
INPPL1 inositol polyphosphate phosphatase-like 1 Mapped by significant region IEA
PTTG1 pituitary tumor-transforming 1 Mapped by significant region IEA
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region IPI[9447983]
ADAM19 ADAM metallopeptidase domain 19 Mapped by significant region IEA
SYNGAP1 synaptic Ras GTPase activating protein 1 Mapped by Literature SNP IEA
MAPT microtubule-associated protein tau Mapped by LD-proxy; Mapped by PBA pathway IPI[9763511]
UVRAG UV radiation resistance associated Mapped by significant region IEA
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region IEA
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IEA
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region NAS[11820818]
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region IPI[7938008]
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region IEA