ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CDC42BPG
Symbol Alias	HSMDPKIN, MRCKgamma, DMPK2, kappa-200
Approved Name	CDC42 binding protein kinase gamma (DMPK-like)
Location	11q13
Position	chr11:64590859-64612041, -
External Links	HGNC: 29829 Entrez Gene: 55561 Ensembl: ENSG00000171219 UCSC: uc001obs.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035556	intracellular signal transduction	Biological Process		44
GO:0031532	actin cytoskeleton reorganization	Biological Process		5
GO:0031252	cell leading edge	Cellular Component	IDA[15194684]	4
GO:0006468	protein phosphorylation	Biological Process	IDA[15194684]; NAS[9341881]	53
GO:0005813	centrosome	Cellular Component		71
GO:0005737	cytoplasm	Cellular Component		690
GO:0005543	phospholipid binding	Molecular Function		61
GO:0005524	ATP binding	Molecular Function	IDA[15194684]; NAS[9341881]	228
GO:0005515	protein binding	Molecular Function		910
GO:0005083	small GTPase regulator activity	Molecular Function		5
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA[15194684]; NAS[9341881]	61
GO:0000287	magnesium ion binding	Molecular Function	IDA[15194684]	28

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CDC42BPG (count: 19)

Gene Symbol	Pathway Count	Pathway List
GSK3B	7	intracellular signal transduction; protein phosphorylation; centrosome; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
ROCK2	7	intracellular signal transduction; protein phosphorylation; centrosome; phospholipid binding; ATP binding; protein binding; protein serine/threonine kinase activity;
PRKCB	6	intracellular signal transduction; protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
PAK1	6	actin cytoskeleton reorganization; protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
MAP3K11	6	protein phosphorylation; centrosome; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
NEK6	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
RPS6KA4	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
SIK2	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
SIK3	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
STK36	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
TSSK2	6	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
ILK	5	protein phosphorylation; cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
LATS1	5	protein phosphorylation; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
MAP4K2	5	protein phosphorylation; ATP binding; protein binding; small GTPase regulator activity; protein serine/threonine kinase activity;
MARK2	5	protein phosphorylation; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
MARK4	5	protein phosphorylation; centrosome; ATP binding; protein binding; protein serine/threonine kinase activity;
PLK1	5	protein phosphorylation; centrosome; ATP binding; protein binding; protein serine/threonine kinase activity;
TSSK4	5	protein phosphorylation; ATP binding; protein binding; protein serine/threonine kinase activity; magnesium ion binding;
PRKD1	5	cytoplasm; phospholipid binding; ATP binding; protein binding; protein serine/threonine kinase activity;

Genes shared at least 2 KEGG pathways with CDC42BPG (count: 0)

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Region: chr11:64590859..64612041 View in gBrowse