ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008284
Name positive regulation of cell proliferation
Type biological process
No. of Genes in ADHDgene  75
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 75)

Literature-origin genes (count: 16)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HES1 hes family bHLH transcription factor 1 3q28-q29 1(1/0/0) ISS
NTF3 neurotrophin 3 12p13 4(1/3/0) IDA
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IEA
EREG epiregulin 4q21.21 1(0/0/1) IDA[10681561]; ISS
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5q31-q33 1(1/0/0) IMP[15925089]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA[17525748]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) ISS
CNTFR ciliary neurotrophic factor receptor 9p13 1(1/0/0) IEA
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IDA[7929439]
ADRA1D adrenoceptor alpha 1D 20p13 1(0/1/0) TAS[10860850]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) TAS[10896916]
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 15q13.3 2(0/1/1) IMP[17498763]
CNTF ciliary neurotrophic factor 11q12 1(1/0/0) IEA
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 5q11.2-q13 2(2/0/0) TAS[1330092]
ISL1 ISL LIM homeobox 1 5q11.2 1(0/1/0) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IEA

Genes from other sources Help (count: 59)

Approved Symbol Approved Name Source Evidence[PMID]
LIFR leukemia inhibitory factor receptor alpha Mapped by significant region IDA[8999038]
FGF4 fibroblast growth factor 4 Mapped by significant region IGI[8663044]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IDA[2261637]; IMP[18719127]
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IMP[18373975]
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region IDA[10438939]
CTF1 cardiotrophin 1 Mapped by CNV TAS[7862649]
TTK TTK protein kinase Mapped by PBA pathway TAS[1639825]
HOXA3 homeobox A3 Mapped by significant region IEA
MVD mevalonate (diphospho) decarboxylase Mapped by significant region IMP[9270019]
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 Mapped by significant region IEA
FGF3 fibroblast growth factor 3 Mapped by significant region IGI[8663044]
ODC1 ornithine decarboxylase 1 Mapped by significant region IEA
GAB2 GRB2-associated binding protein 2 Mapped by significant region IDA[19172738]
ROGDI rogdi homolog (Drosophila) Mapped by significant region IEA
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region IEA
FGF9 fibroblast growth factor 9 Mapped by significant region IDA[8321227]
TNC tenascin C Mapped by significant region IEA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
FGF19 fibroblast growth factor 19 Mapped by significant region IGI[18187602]
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IMP[14633705]
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IEA
GREM1 gremlin 1, DAN family BMP antagonist Mapped by CNV; Mapped by significant region IDA[16545136]
CDCA7L cell division cycle associated 7-like Mapped by significant region IDA[15994933]
RPS9 ribosomal protein S9 Mapped by CNV IMP[18420587]
CAV3 caveolin 3 Mapped by Literature SNP IEA
CDC25B cell division cycle 25B Mapped by CNV TAS[8276402]
RTKN2 rhotekin 2 Mapped by CNV IEA
LRP5 low density lipoprotein receptor-related protein 5 Mapped by CNV; Mapped by significant region IDA[9790987]
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region IEA
CIAO1 cytosolic iron-sulfur assembly component 1 Mapped by LD-proxy TAS[9556563]
CAPN1 calpain 1, (mu/I) large subunit Mapped by significant region TAS[8702541]
PDCD10 programmed cell death 10 Mapped by CNV IDA[17360971]
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 Mapped by significant region TAS[7913952]
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway TAS[2739737]
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
MTA3 metastasis associated 1 family, member 3 Mapped by Literature SNP IEA
PRAMENP PRAME N-terminal-like, pseudogene Mapped by LD-proxy IEA
REG1A regenerating islet-derived 1 alpha Mapped by CNV TAS[2332435]
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 Mapped by significant region TAS[9806637]
ILK integrin-linked kinase Mapped by CNV IEA
BTC betacellulin Mapped by CNV IEA
CLCF1 cardiotrophin-like cytokine factor 1 Mapped by significant region IDA[11285233]
RPS15A ribosomal protein S15a Mapped by significant region IDA[15108328]
IGF2 insulin-like growth factor 2 (somatomedin A) Mapped by LD-proxy IC[11500939]
FOSL1 FOS-like antigen 1 Mapped by significant region TAS[8230424]
TBX1 T-box 1 Mapped by CNV ISS
S1PR3 sphingosine-1-phosphate receptor 3 Mapped by significant region TAS[10617617]
OSMR oncostatin M receptor Mapped by significant region IGI[8999038]
YAP1 Yes-associated protein 1 Mapped by significant region IEA
GAREM GRB2 associated, regulator of MAPK1 Mapped by significant region IDA[19509291]
BIRC6 baculoviral IAP repeat containing 6 Mapped by CNV IEA
FLT4 fms-related tyrosine kinase 4 Mapped by CNV IGI[11574540]; IMP[19779139]
ACER3 alkaline ceramidase 3 Mapped by significant region IMP
CTGF connective tissue growth factor Mapped by significant region IEA
INS insulin Mapped by Literature SNP IDA[17925406]
CCKBR cholecystokinin B receptor Mapped by CNV; Mapped by PBA pathway IDA[10913157]
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) Mapped by CNV IEA
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator Mapped by CNV TAS[9367155]
CHP2 calcineurin-like EF-hand protein 2 Mapped by significant region IDA