ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RDX
Previous Symbol	DFNB24
Approved Name	radixin
Previous Name	deafness, autosomal recessive 24
Location	11q23
Position	chr11:110045605-110167447, -
External Links	HGNC: 9944 Entrez Gene: 5962 Ensembl: ENSG00000137710 UCSC: uc001pku.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)
11q22	chr11:97200000-110400000	1 (1/0/0)

Gene related GO terms (count: 16)

ID	Name	Type	No. of Genes in ADHDgene
GO:0030175	filopodium	Cellular Component	5
GO:0032154	cleavage furrow	Cellular Component	8
GO:0032420	stereocilium	Cellular Component	6
GO:0045176	apical protein localization	Biological Process	4
GO:0005925	focal adhesion	Cellular Component	26
GO:0019898	extrinsic to membrane	Cellular Component	8
GO:0030027	lamellipodium	Cellular Component	27
GO:0030033	microvillus assembly	Biological Process	1
GO:0045177	apical part of cell	Cellular Component	12
GO:0051693	actin filament capping	Biological Process	3
GO:0005737	cytoplasm	Cellular Component	690
GO:0005515	protein binding	Molecular Function	910
GO:0005886	plasma membrane	Cellular Component	772
GO:0005856	cytoskeleton	Cellular Component	54
GO:0003779	actin binding	Molecular Function	46
GO:0001726	ruffle	Cellular Component	14

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04810	Regulation of actin cytoskeleton	48

Genes shared at least 5 GO terms with RDX (count: 11)

Gene Symbol	Pathway Count	Pathway List
NF2	7	cleavage furrow; extrinsic to membrane; lamellipodium; cytoplasm; protein binding; plasma membrane; cytoskeleton;
VIL1	6	filopodium; lamellipodium; actin filament capping; cytoplasm; protein binding; ruffle;
BAIAP2	5	filopodium; cytoplasm; protein binding; plasma membrane; ruffle;
ARPC2	5	focal adhesion; cytoplasm; protein binding; plasma membrane; actin binding;
BCAR1	5	focal adhesion; cytoplasm; protein binding; plasma membrane; ruffle;
ILK	5	focal adhesion; lamellipodium; cytoplasm; protein binding; plasma membrane;
PAK1	5	focal adhesion; cytoplasm; protein binding; plasma membrane; ruffle;
TNS1	5	focal adhesion; cytoplasm; protein binding; cytoskeleton; actin binding;
CTTN	5	lamellipodium; cytoplasm; protein binding; cytoskeleton; ruffle;
INPPL1	5	lamellipodium; cytoplasm; protein binding; plasma membrane; actin binding;
FLNC	5	cytoplasm; protein binding; plasma membrane; cytoskeleton; actin binding;

Genes shared at least 2 KEGG pathways with RDX (count: 0)

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Region: chr11:110045605..110167447 View in gBrowse