ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GAK
Approved Name	cyclin G associated kinase
Location	4p16
Position	chr4:843064-926174, -
External Links	HGNC: 4113 Entrez Gene: 2580 Ensembl: ENSG00000178950 UCSC: uc003gbm.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 4)

rs_ID	Location	Functional Annotation
rs8093	Chr4:843695(Fwd)	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant
rs2306248	Chr4:860146(Fwd)	intron_variant; nc_transcript_variant; splice_region_variant
rs4690332	Chr4:910520(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant
rs7663192	Chr4:923947(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 9)

ID	Name	Type	No. of Genes in ADHDgene
GO:0004674	protein serine/threonine kinase activity	Molecular Function	61
GO:0031072	heat shock protein binding	Molecular Function	10
GO:0048471	perinuclear region of cytoplasm	Cellular Component	87
GO:0005925	focal adhesion	Cellular Component	26
GO:0007049	cell cycle	Biological Process	31
GO:0005737	cytoplasm	Cellular Component	690
GO:0005794	Golgi apparatus	Cellular Component	157
GO:0005515	protein binding	Molecular Function	910
GO:0005524	ATP binding	Molecular Function	228

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GAK (count: 7)

Gene Symbol	Pathway Count	Pathway List
MAPK1	7	protein serine/threonine kinase activity; focal adhesion; cell cycle; cytoplasm; Golgi apparatus; protein binding; ATP binding;
PAK1	6	protein serine/threonine kinase activity; focal adhesion; cytoplasm; Golgi apparatus; protein binding; ATP binding;
GSK3B	5	protein serine/threonine kinase activity; perinuclear region of cytoplasm; cytoplasm; protein binding; ATP binding;
ILK	5	protein serine/threonine kinase activity; focal adhesion; cytoplasm; protein binding; ATP binding;
PRKD1	5	protein serine/threonine kinase activity; cytoplasm; Golgi apparatus; protein binding; ATP binding;
SIK2	5	protein serine/threonine kinase activity; cytoplasm; Golgi apparatus; protein binding; ATP binding;
MAPK3	5	focal adhesion; cell cycle; Golgi apparatus; protein binding; ATP binding;

Genes shared at least 2 KEGG pathways with GAK (count: 0)

View in gBrowse

Region: chr4:843064..926174 View in gBrowse