ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	AKAP7
Symbol Alias	AKAP18, AKAP15
Approved Name	A kinase (PRKA) anchor protein 7
Location	6q23.2
Position	chr6:131456806-131604675, 1
External Links	HGNC: 377 Entrez Gene: 9465 Ensembl: ENSG00000118507 UCSC: uc003qck.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 24)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 24)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016529	sarcoplasmic reticulum	cellular component	IEA	12
GO:0008022	protein C-terminus binding	molecular function	IEA	42
GO:0016324	apical plasma membrane	cellular component	IDA[10613906]; IEA	52
GO:0019904	protein domain specific binding	molecular function	IEA	43
GO:0003824	catalytic activity	molecular function	IEA	15
GO:0008150	biological_process	biological process	ND	127
GO:0010738	regulation of protein kinase A signaling cascade	biological process	IEA	2
GO:0005829	cytosol	cellular component	IDA[10613906]	485
GO:0032947	protein complex scaffold	molecular function	IEA	7
GO:0030315	T-tubule	cellular component	IEA	12
GO:0016208	AMP binding	molecular function	IEA	3
GO:0070382	exocytic vesicle	cellular component	IEA	3
GO:0034237	protein kinase A regulatory subunit binding	molecular function	IEA	2
GO:0043234	protein complex	cellular component	IEA	47
GO:0008104	protein localization	biological process	IC[9545239]	12
GO:0016328	lateral plasma membrane	cellular component	IDA[10613906]	10
GO:0005886	plasma membrane	cellular component	TAS[10613906]	839
GO:0016070	RNA metabolic process	biological process	IEA	54
GO:0035556	intracellular signal transduction	biological process	TAS[10613906]	52
GO:0019901	protein kinase binding	molecular function	IEA	59
GO:0051018	protein kinase A binding	molecular function	IDA[9545239]; TAS[10613906]	2
GO:0005634	nucleus	cellular component	IEA	877
GO:0006811	ion transport	biological process	TAS[9545239]	32
GO:0005515	protein binding	molecular function	IPI[17244820]	1015

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AKAP7 (count: 30)

Gene Symbol	Pathway Count	Pathway List
AXIN1	8	protein C-terminus binding; cytosol; protein complex scaffold; lateral plasma membrane; plasma membrane; protein kinase binding; nucleus; protein binding;
CAV3	6	protein C-terminus binding; protein complex scaffold; T-tubule; protein localization; plasma membrane; protein binding;
CEP250	6	protein C-terminus binding; cytosol; protein complex; protein localization; protein kinase binding; protein binding;
TJP1	6	protein C-terminus binding; protein domain specific binding; cytosol; plasma membrane; nucleus; protein binding;
ARRB2	6	protein domain specific binding; cytosol; protein complex scaffold; plasma membrane; nucleus; protein binding;
APC	6	cytosol; lateral plasma membrane; plasma membrane; protein kinase binding; nucleus; protein binding;
GSK3B	6	cytosol; plasma membrane; intracellular signal transduction; protein kinase binding; nucleus; protein binding;
RYR2	5	sarcoplasmic reticulum; protein kinase A regulatory subunit binding; protein complex; plasma membrane; protein binding;
ERBB2	5	protein C-terminus binding; apical plasma membrane; plasma membrane; nucleus; protein binding;
PRKAA1	5	protein C-terminus binding; apical plasma membrane; cytosol; nucleus; protein binding;
SLC9A3R2	5	protein C-terminus binding; apical plasma membrane; plasma membrane; nucleus; protein binding;
CORO1A	5	protein C-terminus binding; protein complex; plasma membrane; nucleus; protein binding;
BAIAP2	5	protein C-terminus binding; cytosol; plasma membrane; nucleus; protein binding;
STXBP3	5	apical plasma membrane; cytosol; plasma membrane; nucleus; protein binding;
THY1	5	apical plasma membrane; cytosol; plasma membrane; protein kinase binding; protein binding;
SLC3A2	5	apical plasma membrane; catalytic activity; plasma membrane; ion transport; protein binding;
SNCA	5	protein domain specific binding; cytosol; plasma membrane; nucleus; protein binding;
NCK1	5	protein domain specific binding; cytosol; plasma membrane; nucleus; protein binding;
CTNND1	5	protein domain specific binding; cytosol; plasma membrane; nucleus; protein binding;
AIP	5	regulation of protein kinase A signaling cascade; cytosol; plasma membrane; nucleus; protein binding;
MALT1	5	cytosol; protein complex; plasma membrane; nucleus; protein binding;
HSPA8	5	cytosol; plasma membrane; RNA metabolic process; nucleus; protein binding;
ROCK2	5	cytosol; plasma membrane; intracellular signal transduction; nucleus; protein binding;
PARN	5	cytosol; RNA metabolic process; protein kinase binding; nucleus; protein binding;
PAK1	5	cytosol; protein complex; plasma membrane; protein kinase binding; protein binding;
SQSTM1	5	cytosol; protein localization; intracellular signal transduction; protein kinase binding; protein binding;
RPS3	5	cytosol; RNA metabolic process; protein kinase binding; nucleus; protein binding;
CLNS1A	5	cytosol; plasma membrane; RNA metabolic process; nucleus; protein binding;
ILK	5	cytosol; protein complex; plasma membrane; protein kinase binding; protein binding;
PDPK1	5	cytosol; plasma membrane; intracellular signal transduction; protein kinase binding; protein binding;

Genes shared at least 2 KEGG pathways with AKAP7 (count: 0)

View in gBrowse

Region: chr6:131456806..131604675 View in gBrowse