Gene Symbol |
Pathway Count |
Pathway List |
STK11 |
11 |
autophagy;
regulation of fatty acid oxidation;
insulin receptor signaling pathway;
protein binding;
protein heterooligomerization;
protein phosphorylation;
cell cycle arrest;
nucleus;
glucose homeostasis;
ATP binding;
cytosol;
|
INS |
10 |
fatty acid homeostasis;
negative regulation of apoptotic process;
insulin receptor signaling pathway;
glucose metabolic process;
protein binding;
positive regulation of cell proliferation;
glucose homeostasis;
negative regulation of lipid catabolic process;
regulation of transcription, DNA-dependent;
positive regulation of glycolysis;
|
TGFBR1 |
10 |
negative regulation of apoptotic process;
signal transduction;
protein binding;
protein phosphorylation;
cell cycle arrest;
positive regulation of cell proliferation;
metal ion binding;
protein kinase activity;
ATP binding;
regulation of transcription, DNA-dependent;
|
MAPK1 |
10 |
response to stress;
insulin receptor signaling pathway;
signal transduction;
activation of MAPK activity;
protein binding;
transcription, DNA-dependent;
nucleus;
positive regulation of cell proliferation;
ATP binding;
cytosol;
|
MAP2K5 |
9 |
negative regulation of apoptotic process;
signal transduction;
activation of MAPK activity;
protein binding;
nucleus;
metal ion binding;
protein kinase activity;
ATP binding;
cytosol;
|
PRKAB2 |
9 |
regulation of fatty acid oxidation;
insulin receptor signaling pathway;
signal transduction;
protein binding;
fatty acid biosynthetic process;
cell cycle arrest;
AMP-activated protein kinase complex;
AMP-activated protein kinase activity;
cytosol;
|
PRKAG3 |
8 |
regulation of fatty acid oxidation;
insulin receptor signaling pathway;
fatty acid biosynthetic process;
cell cycle arrest;
AMP-activated protein kinase complex;
AMP-activated protein kinase activity;
ATP binding;
cytosol;
|
TSC2 |
8 |
insulin receptor signaling pathway;
protein binding;
protein heterooligomerization;
negative regulation of TOR signaling cascade;
cell cycle arrest;
nucleus;
cytosol;
response to hypoxia;
|
ERBB2 |
8 |
signal transduction;
protein binding;
apical plasma membrane;
protein phosphorylation;
transcription, DNA-dependent;
nucleus;
protein C-terminus binding;
ATP binding;
|
CRYAB |
7 |
negative regulation of apoptotic process;
glucose metabolic process;
protein binding;
nucleus;
metal ion binding;
cytosol;
response to hypoxia;
|
PLK1 |
7 |
negative regulation of apoptotic process;
protein binding;
protein phosphorylation;
nucleus;
protein kinase activity;
ATP binding;
cytosol;
|
TFAP2B |
7 |
negative regulation of apoptotic process;
glucose metabolic process;
protein binding;
nucleus;
positive regulation of cell proliferation;
glucose homeostasis;
regulation of transcription, DNA-dependent;
|
ATM |
7 |
negative regulation of apoptotic process;
signal transduction;
protein binding;
histone serine kinase activity;
cell cycle arrest;
ATP binding;
response to hypoxia;
|
MAPK7 |
7 |
negative regulation of apoptotic process;
signal transduction;
protein binding;
nucleus;
cellular response to hydrogen peroxide;
ATP binding;
cytosol;
|
GSK3B |
7 |
negative regulation of apoptotic process;
protein binding;
tau-protein kinase activity;
protein phosphorylation;
nucleus;
ATP binding;
cytosol;
|
SMG1 |
7 |
response to stress;
protein binding;
nucleus;
metal ion binding;
protein kinase activity;
ATP binding;
cytosol;
|
PRKAG2 |
7 |
regulation of fatty acid oxidation;
insulin receptor signaling pathway;
fatty acid biosynthetic process;
cell cycle arrest;
AMP-activated protein kinase complex;
ATP binding;
cytosol;
|
CREBBP |
7 |
cellular response to hypoxia;
signal transduction;
protein binding;
nucleus;
regulation of transcription, DNA-dependent;
chromatin binding;
response to hypoxia;
|
MAPK3 |
7 |
insulin receptor signaling pathway;
activation of MAPK activity;
protein binding;
protein phosphorylation;
nucleus;
ATP binding;
cytosol;
|
PDPK1 |
7 |
insulin receptor signaling pathway;
protein binding;
protein phosphorylation;
transcription, DNA-dependent;
ATP binding;
regulation of transcription, DNA-dependent;
cytosol;
|
SREBF1 |
7 |
insulin receptor signaling pathway;
protein binding;
transcription, DNA-dependent;
nucleus;
positive regulation of cholesterol biosynthetic process;
lipid biosynthetic process;
chromatin binding;
|
CSNK1E |
7 |
signal transduction;
protein binding;
protein phosphorylation;
nucleus;
protein kinase activity;
ATP binding;
cytosol;
|
APBB1 |
7 |
signal transduction;
protein binding;
cell cycle arrest;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
chromatin binding;
|
TLE1 |
7 |
signal transduction;
protein binding;
nucleus;
Wnt receptor signaling pathway;
positive regulation of gene expression;
cytosol;
chromatin binding;
|
TNNI3K |
7 |
protein binding;
protein phosphorylation;
nucleus;
metal ion binding;
protein kinase activity;
protein C-terminus binding;
ATP binding;
|
ILK |
7 |
protein binding;
protein heterooligomerization;
protein phosphorylation;
cell cycle arrest;
positive regulation of cell proliferation;
ATP binding;
cytosol;
|
BNIP3 |
6 |
negative regulation of apoptotic process;
cellular response to hypoxia;
protein binding;
nucleus;
cellular response to hydrogen peroxide;
response to hypoxia;
|
VEGFA |
6 |
negative regulation of apoptotic process;
cellular response to hypoxia;
protein binding;
positive regulation of cell proliferation;
positive regulation of gene expression;
response to hypoxia;
|
XRCC5 |
6 |
negative regulation of apoptotic process;
protein binding;
transcription, DNA-dependent;
nucleus;
protein C-terminus binding;
ATP binding;
|
BIRC2 |
6 |
negative regulation of apoptotic process;
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
DAB2 |
6 |
negative regulation of apoptotic process;
protein binding;
apical plasma membrane;
nucleus;
Wnt receptor signaling pathway;
protein C-terminus binding;
|
YAP1 |
6 |
negative regulation of apoptotic process;
protein binding;
nucleus;
positive regulation of cell proliferation;
cytosol;
chromatin binding;
|
RELA |
6 |
negative regulation of apoptotic process;
protein binding;
nucleus;
positive regulation of cell proliferation;
cytosol;
chromatin binding;
|
DNAJA3 |
6 |
negative regulation of apoptotic process;
protein binding;
nucleus;
metal ion binding;
ATP binding;
cytosol;
|
FGF4 |
6 |
negative regulation of apoptotic process;
insulin receptor signaling pathway;
signal transduction;
nucleus;
positive regulation of cell proliferation;
cytosol;
|
TSC1 |
6 |
insulin receptor signaling pathway;
protein binding;
protein heterooligomerization;
negative regulation of TOR signaling cascade;
cell cycle arrest;
cytosol;
|
PRKD1 |
6 |
signal transduction;
protein binding;
nucleus;
metal ion binding;
ATP binding;
cytosol;
|
EEF1D |
6 |
signal transduction;
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
RIPK3 |
6 |
signal transduction;
protein binding;
protein heterooligomerization;
protein kinase activity;
ATP binding;
cytosol;
|
HSPA8 |
6 |
protein binding;
transcription, DNA-dependent;
nucleus;
intracellular;
ATP binding;
cytosol;
|
ETS1 |
6 |
protein binding;
transcription, DNA-dependent;
nucleus;
positive regulation of cell proliferation;
cellular response to hydrogen peroxide;
response to hypoxia;
|
HINFP |
6 |
protein binding;
transcription, DNA-dependent;
nucleus;
positive regulation of gene expression;
regulation of transcription, DNA-dependent;
chromatin binding;
|
CTNND1 |
6 |
protein binding;
transcription, DNA-dependent;
nucleus;
Wnt receptor signaling pathway;
regulation of transcription, DNA-dependent;
cytosol;
|
LATS2 |
6 |
protein binding;
protein phosphorylation;
nucleus;
metal ion binding;
ATP binding;
cytosol;
|
PAK1 |
6 |
protein binding;
protein phosphorylation;
protein kinase activity;
ATP binding;
cytosol;
response to hypoxia;
|
MARK2 |
6 |
protein binding;
tau-protein kinase activity;
protein phosphorylation;
nucleus;
Wnt receptor signaling pathway;
ATP binding;
|
MEN1 |
6 |
protein binding;
cell cycle arrest;
transcription, DNA-dependent;
nucleus;
cytosol;
chromatin binding;
|
ROCK2 |
6 |
protein binding;
protein phosphorylation;
nucleus;
metal ion binding;
ATP binding;
cytosol;
|
CNOT6 |
6 |
protein binding;
transcription, DNA-dependent;
nucleus;
metal ion binding;
regulation of transcription, DNA-dependent;
cytosol;
|
GATA6 |
5 |
negative regulation of apoptotic process;
cellular response to hypoxia;
protein binding;
nucleus;
chromatin binding;
|
BARD1 |
5 |
negative regulation of apoptotic process;
protein binding;
kinase binding;
cell cycle arrest;
nucleus;
|
PIK3R1 |
5 |
negative regulation of apoptotic process;
insulin receptor signaling pathway;
protein binding;
protein phosphorylation;
cytosol;
|
APC |
5 |
negative regulation of apoptotic process;
protein binding;
cell cycle arrest;
nucleus;
cytosol;
|
PIK3CG |
5 |
negative regulation of apoptotic process;
protein binding;
protein kinase activity;
ATP binding;
cytosol;
|
FLT4 |
5 |
negative regulation of apoptotic process;
protein binding;
nucleus;
positive regulation of cell proliferation;
ATP binding;
|
MED1 |
5 |
negative regulation of apoptotic process;
protein binding;
nucleus;
positive regulation of gene expression;
chromatin binding;
|
GSTP1 |
5 |
negative regulation of apoptotic process;
protein binding;
nucleus;
intracellular;
cytosol;
|
TNFAIP3 |
5 |
negative regulation of apoptotic process;
protein binding;
kinase binding;
nucleus;
cytosol;
|
CBL |
5 |
negative regulation of apoptotic process;
protein binding;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
HSPA5 |
5 |
negative regulation of apoptotic process;
protein binding;
cellular response to glucose starvation;
nucleus;
ATP binding;
|
KDM1A |
5 |
negative regulation of apoptotic process;
protein binding;
transcription, DNA-dependent;
nucleus;
chromatin binding;
|
SQSTM1 |
5 |
autophagy;
response to stress;
protein binding;
protein heterooligomerization;
cytosol;
|
MAPK9 |
5 |
response to stress;
protein binding;
positive regulation of gene expression;
ATP binding;
cytosol;
|
ATF6 |
5 |
response to stress;
signal transduction;
protein binding;
transcription, DNA-dependent;
nucleus;
|
ERN2 |
5 |
response to stress;
protein phosphorylation;
cell cycle arrest;
transcription, DNA-dependent;
ATP binding;
|
FLCN |
5 |
response to stress;
protein binding;
negative regulation of TOR signaling cascade;
nucleus;
positive regulation of gene expression;
|
BAD |
5 |
cellular response to hypoxia;
protein binding;
positive regulation of autophagy;
glucose homeostasis;
cytosol;
|
UBB |
5 |
cellular response to hypoxia;
activation of MAPK activity;
protein binding;
transcription, DNA-dependent;
cytosol;
|
UBC |
5 |
cellular response to hypoxia;
activation of MAPK activity;
protein binding;
transcription, DNA-dependent;
cytosol;
|
EGLN3 |
5 |
cellular response to hypoxia;
protein binding;
nucleus;
cytosol;
response to hypoxia;
|
PMAIP1 |
5 |
cellular response to hypoxia;
protein binding;
cellular response to glucose starvation;
nucleus;
cytosol;
|
RPTOR |
5 |
insulin receptor signaling pathway;
protein binding;
cell cycle arrest;
cellular response to nutrient levels;
cytosol;
|
PIK3C3 |
5 |
insulin receptor signaling pathway;
protein binding;
protein kinase activity;
ATP binding;
cytosol;
|
SIK2 |
5 |
insulin receptor signaling pathway;
protein binding;
protein phosphorylation;
nucleus;
ATP binding;
|
IGF2 |
5 |
insulin receptor signaling pathway;
glucose metabolic process;
protein binding;
positive regulation of cell proliferation;
regulation of transcription, DNA-dependent;
|
BAIAP2 |
5 |
insulin receptor signaling pathway;
protein binding;
nucleus;
protein C-terminus binding;
cytosol;
|
PHKG2 |
5 |
glucose metabolic process;
tau-protein kinase activity;
protein phosphorylation;
ATP binding;
cytosol;
|
CTNND2 |
5 |
signal transduction;
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
|
LPXN |
5 |
signal transduction;
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
|
NR4A2 |
5 |
signal transduction;
protein binding;
transcription, DNA-dependent;
nucleus;
response to hypoxia;
|
NEK6 |
5 |
signal transduction;
protein binding;
protein phosphorylation;
nucleus;
ATP binding;
|
FYB |
5 |
signal transduction;
protein binding;
protein phosphorylation;
nucleus;
cytosol;
|
PRKG1 |
5 |
signal transduction;
protein binding;
protein phosphorylation;
ATP binding;
cytosol;
|
TXN |
5 |
signal transduction;
response to activity;
protein binding;
transcription, DNA-dependent;
cytosol;
|
MAP2K3 |
5 |
signal transduction;
activation of MAPK activity;
protein binding;
ATP binding;
cytosol;
|
SMC3 |
5 |
signal transduction;
protein binding;
nucleus;
ATP binding;
chromatin binding;
|
ITK |
5 |
signal transduction;
protein binding;
metal ion binding;
ATP binding;
cytosol;
|
ADRA2A |
5 |
signal transduction;
protein binding;
positive regulation of cell proliferation;
glucose homeostasis;
negative regulation of lipid catabolic process;
|
ADRBK1 |
5 |
signal transduction;
protein binding;
protein kinase activity;
ATP binding;
cytosol;
|
TH |
5 |
response to activity;
protein binding;
nucleus;
cytosol;
response to hypoxia;
|
MAP3K11 |
5 |
activation of MAPK activity;
protein binding;
protein phosphorylation;
protein kinase activity;
ATP binding;
|
STXBP3 |
5 |
protein binding;
protein heterooligomerization;
apical plasma membrane;
nucleus;
cytosol;
|
HABP4 |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
HMGA1 |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
CCND1 |
5 |
protein binding;
nucleus;
protein kinase activity;
intracellular;
cytosol;
|
JMJD1C |
5 |
protein binding;
transcription, DNA-dependent;
metal ion binding;
intracellular;
regulation of transcription, DNA-dependent;
|
SYK |
5 |
protein binding;
protein phosphorylation;
protein kinase activity;
ATP binding;
cytosol;
|
RQCD1 |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
DAXX |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
WASL |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
regulation of transcription, DNA-dependent;
cytosol;
|
KAT5 |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
metal ion binding;
cytosol;
|
AKAP7 |
5 |
protein binding;
apical plasma membrane;
nucleus;
protein C-terminus binding;
cytosol;
|
NEDD4L |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
intracellular;
cytosol;
|
FRK |
5 |
protein binding;
protein phosphorylation;
nucleus;
intracellular;
ATP binding;
|
RPS6KA4 |
5 |
protein binding;
protein phosphorylation;
nucleus;
ATP binding;
regulation of transcription, DNA-dependent;
|
ACACA |
5 |
protein binding;
fatty acid biosynthetic process;
metal ion binding;
ATP binding;
cytosol;
|
IGHMBP2 |
5 |
protein binding;
transcription, DNA-dependent;
nucleus;
ATP binding;
regulation of transcription, DNA-dependent;
|
IL18 |
5 |
apical plasma membrane;
cellular response to hydrogen peroxide;
positive regulation of gene expression;
cytosol;
response to hypoxia;
|
RNASEL |
5 |
protein phosphorylation;
metal ion binding;
protein kinase activity;
ATP binding;
cytosol;
|
HBP1 |
5 |
cell cycle arrest;
transcription, DNA-dependent;
nucleus;
Wnt receptor signaling pathway;
regulation of transcription, DNA-dependent;
|