ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0004672
Name protein kinase activity
Type molecular function
No. of Genes in ADHDgene  31
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DCLK1 doublecortin-like kinase 1 13q13.3 1(1/0/0) TAS[9747029]
CSNK1E casein kinase 1, epsilon 22q13.1 2(1/1/0) ISS
ADRBK2 adrenergic, beta, receptor kinase 2 22q11 1(0/1/0) TAS[8427589]
MAP2K5 mitogen-activated protein kinase kinase 5 15q22.31 1(1/0/0) TAS[7759517]
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) ISS
TNNI3K TNNI3 interacting kinase 1p31.1 1(0/1/0) IDA[12721663]

Genes from other sources Help (count: 25)

Approved Symbol Approved Name Source Evidence[PMID]
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region TAS[8183572]
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) Mapped by significant region IEA
CCND1 cyclin D1 Mapped by significant region IEA
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 Mapped by significant region IEA
MLKL mixed lineage kinase domain-like Mapped by significant region IEA
FASTKD3 FAST kinase domains 3 Mapped by significant region IEA
AURKC aurora kinase C Mapped by LD-proxy IDA[15670791]
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region IDA[17028174]
EEF2K eukaryotic elongation factor-2 kinase Mapped by CNV; Mapped by significant region TAS[9144159]
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase Mapped by significant region TAS[14636577]
FASTKD5 FAST kinase domains 5 Mapped by CNV IEA
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 Mapped by significant region TAS[9001210]
RIPK3 receptor-interacting serine-threonine kinase 3 Mapped by significant region TAS[10358032]
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA
SYK spleen tyrosine kinase Mapped by significant region NAS[12885943]
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[19736306]
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region IDA[9852149]
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) Mapped by CNV TAS[9000130]
PLK1 polo-like kinase 1 Mapped by significant region IDA[17146433]
CDK12 cyclin-dependent kinase 12 Mapped by LD-proxy IDA[11683387]
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region TAS[9804755]
POLR2G polymerase (RNA) II (DNA directed) polypeptide G Mapped by significant region IDA[9852112]
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa Mapped by CNV IDA[9852112]
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Mapped by CNV TAS[19376709]
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway IEA