ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ADRBK2
Symbol Alias	GRK3, BARK2
Approved Name	adrenergic, beta, receptor kinase 2
Location	22q11
Position	chr22:25960816-26125261, 1
External Links	HGNC: 290 Entrez Gene: 157 Ensembl: ENSG00000100077 UCSC: uc003abx.4
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Brookes K, 2006	UNPHASED TDT P-value=0.145, global P-value=0.747, WHAP TDT P_sum P-value=0.573, no SNP with nominal P-value<0.05 located in this gene	Non-significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0038032	termination of G-protein coupled receptor signaling pathway	biological process	IEA	11
GO:0004672	protein kinase activity	molecular function	TAS[8427589]	31
GO:0047696	beta-adrenergic receptor kinase activity	molecular function	IEA	2
GO:0004703	G-protein coupled receptor kinase activity	molecular function	IEA	2
GO:0005524	ATP binding	molecular function	IEA	265
GO:0007165	signal transduction	biological process	IEA	189
GO:0031623	receptor internalization	biological process	IDA	10
GO:0005543	phospholipid binding	molecular function	IEA	66

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04740	Olfactory transduction	170

Genes shared at least 5 GO terms with ADRBK2 (count: 1)

Gene Symbol	Pathway Count	Pathway List
ADRBK1	8	termination of G-protein coupled receptor signaling pathway; protein kinase activity; beta-adrenergic receptor kinase activity; G-protein coupled receptor kinase activity; ATP binding; signal transduction; receptor internalization; phospholipid binding;

Genes shared at least 2 KEGG pathways with ADRBK2 (count: 0)

View in gBrowse

Region: chr22:25960816..26125261 View in gBrowse