Gene Symbol |
Pathway Count |
Pathway List |
UBB |
67 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
regulation of apoptotic process;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
T cell receptor signaling pathway;
positive regulation of NF-kappaB transcription factor activity;
egress of virus within host cell;
nerve growth factor receptor signaling pathway;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
stress-activated MAPK cascade;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
nucleotide-binding oligomerization domain containing signaling pathway;
cellular response to hypoxia;
regulation of transcription from RNA polymerase II promoter in response to hypoxia;
epidermal growth factor receptor signaling pathway;
transforming growth factor beta receptor signaling pathway;
Notch signaling pathway;
Notch receptor processing;
I-kappaB kinase/NF-kappaB cascade;
JNK cascade;
Toll signaling pathway;
fibroblast growth factor receptor signaling pathway;
endosome membrane;
gene expression;
viral reproduction;
cellular membrane organization;
RNA metabolic process;
mRNA metabolic process;
cytokine-mediated signaling pathway;
endosomal transport;
negative regulation of transforming growth factor beta receptor signaling pathway;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
endocytic vesicle membrane;
cellular response to stress;
negative regulation of type I interferon production;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
negative regulation of epidermal growth factor receptor signaling pathway;
cell cycle checkpoint;
G1 phase of mitotic cell cycle;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
negative regulation of transcription from RNA polymerase II promoter;
activation of MAPK activity;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
toll-like receptor signaling pathway;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
DNA repair;
plasma membrane;
|
PSMB7 |
23 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
PSMC3 |
23 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
PSMD5 |
23 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
PSMD7 |
23 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
MAPK3 |
22 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
nerve growth factor receptor signaling pathway;
stress-activated MAPK cascade;
epidermal growth factor receptor signaling pathway;
Toll signaling pathway;
fibroblast growth factor receptor signaling pathway;
gene expression;
cytokine-mediated signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
activation of MAPK activity;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
apoptotic process;
|
PSME1 |
22 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
PSME2 |
22 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
MAPK1 |
21 |
innate immune response;
T cell receptor signaling pathway;
nerve growth factor receptor signaling pathway;
stress-activated MAPK cascade;
epidermal growth factor receptor signaling pathway;
Toll signaling pathway;
fibroblast growth factor receptor signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
activation of MAPK activity;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
apoptotic process;
transcription, DNA-dependent;
|
RELA |
19 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
T cell receptor signaling pathway;
positive regulation of NF-kappaB transcription factor activity;
nerve growth factor receptor signaling pathway;
Toll signaling pathway;
cytokine-mediated signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
|
PSMA8 |
19 |
regulation of apoptotic process;
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cell cycle checkpoint;
mitotic cell cycle;
protein polyubiquitination;
M/G1 transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
apoptotic process;
|
MAPK7 |
17 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
nerve growth factor receptor signaling pathway;
stress-activated MAPK cascade;
Toll signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
apoptotic process;
|
TLR4 |
17 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
I-kappaB kinase/NF-kappaB cascade;
Toll signaling pathway;
endosome membrane;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
activation of MAPK activity;
protein binding;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
plasma membrane;
|
MAP2K3 |
15 |
innate immune response;
stress-activated MAPK cascade;
Toll signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
activation of MAPK activity;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
|
MAPK9 |
15 |
innate immune response;
stress-activated MAPK cascade;
JNK cascade;
Toll signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
|
IRF7 |
13 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
Toll signaling pathway;
endosome membrane;
cytokine-mediated signaling pathway;
toll-like receptor 4 signaling pathway;
toll-like receptor 3 signaling pathway;
TRIF-dependent toll-like receptor signaling pathway;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
MyD88-independent toll-like receptor signaling pathway;
|
TIRAP |
12 |
innate immune response;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
I-kappaB kinase/NF-kappaB cascade;
Toll signaling pathway;
toll-like receptor 2 signaling pathway;
toll-like receptor 1 signaling pathway;
toll-like receptor 4 signaling pathway;
protein binding;
MyD88-dependent toll-like receptor signaling pathway;
toll-like receptor signaling pathway;
plasma membrane;
|
XPO1 |
11 |
transforming growth factor beta receptor signaling pathway;
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
negative regulation of transforming growth factor beta receptor signaling pathway;
mitotic cell cycle;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
|
MEN1 |
10 |
positive regulation of transcription from RNA polymerase II promoter;
transforming growth factor beta receptor signaling pathway;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
DNA repair;
|
MALT1 |
9 |
innate immune response;
regulation of apoptotic process;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
T cell receptor signaling pathway;
positive regulation of NF-kappaB transcription factor activity;
protease binding;
cytosol;
protein binding;
plasma membrane;
|
E2F5 |
9 |
positive regulation of transcription from RNA polymerase II promoter;
transforming growth factor beta receptor signaling pathway;
gene expression;
G1 phase of mitotic cell cycle;
mitotic cell cycle;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
|
CDC26 |
9 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
cell cycle checkpoint;
mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
|
NEDD4L |
9 |
transforming growth factor beta receptor signaling pathway;
gene expression;
negative regulation of transforming growth factor beta receptor signaling pathway;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
|
SKP2 |
9 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
G1 phase of mitotic cell cycle;
mitotic cell cycle;
protein polyubiquitination;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
|
PRKD1 |
8 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
cytosol;
protein binding;
apoptotic process;
plasma membrane;
|
PIK3R1 |
8 |
positive regulation of transcription from RNA polymerase II promoter;
T cell receptor signaling pathway;
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
BAD |
8 |
nerve growth factor receptor signaling pathway;
cellular response to hypoxia;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytokine-mediated signaling pathway;
cytosol;
protein binding;
apoptotic process;
|
ANAPC4 |
8 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
cell cycle checkpoint;
mitotic cell cycle;
cytosol;
nucleoplasm;
|
PLK1 |
8 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
mitotic cell cycle;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
|
TCEB1 |
8 |
cellular response to hypoxia;
regulation of transcription from RNA polymerase II promoter in response to hypoxia;
gene expression;
viral reproduction;
cellular response to stress;
cytosol;
nucleoplasm;
protein binding;
|
NCOR1 |
8 |
transforming growth factor beta receptor signaling pathway;
Notch signaling pathway;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
|
NCOR2 |
8 |
transforming growth factor beta receptor signaling pathway;
Notch signaling pathway;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
|
HSPA8 |
8 |
gene expression;
cellular membrane organization;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
transcription, DNA-dependent;
plasma membrane;
|
FADD |
7 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
protease binding;
cytosol;
protein binding;
apoptotic process;
|
TNFAIP3 |
7 |
innate immune response;
nucleotide-binding oligomerization domain containing signaling pathway;
negative regulation of type I interferon production;
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;
protease binding;
cytosol;
protein binding;
|
TXN |
7 |
innate immune response;
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
|
GSK3B |
7 |
positive regulation of transcription from RNA polymerase II promoter;
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
NR4A2 |
7 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
cellular response to stress;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
transcription, DNA-dependent;
|
RBPJ |
7 |
positive regulation of transcription from RNA polymerase II promoter;
Notch signaling pathway;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
SNW1 |
7 |
positive regulation of transcription from RNA polymerase II promoter;
Notch signaling pathway;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
SQSTM1 |
7 |
positive regulation of transcription from RNA polymerase II promoter;
nerve growth factor receptor signaling pathway;
endosomal transport;
cytosol;
nucleoplasm;
protein binding;
apoptotic process;
|
BCAR1 |
7 |
regulation of apoptotic process;
T cell receptor signaling pathway;
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
PRKCB |
7 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
cytosol;
protein binding;
apoptotic process;
transcription, DNA-dependent;
plasma membrane;
|
EGLN3 |
7 |
cellular response to hypoxia;
regulation of transcription from RNA polymerase II promoter in response to hypoxia;
cellular response to stress;
cytosol;
nucleoplasm;
protein binding;
apoptotic process;
|
NCBP1 |
7 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
RQCD1 |
7 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytokine-mediated signaling pathway;
cytosol;
protein binding;
transcription, DNA-dependent;
|
CDC45 |
7 |
cell cycle checkpoint;
mitotic cell cycle;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
protein binding;
|
CCND1 |
7 |
G1 phase of mitotic cell cycle;
mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
|
CDT1 |
7 |
mitotic cell cycle;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
|
CASP1 |
6 |
innate immune response;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;
cytosol;
protein binding;
apoptotic process;
|
NCF2 |
6 |
innate immune response;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
cytosol;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
|
RIPK3 |
6 |
innate immune response;
positive regulation of NF-kappaB transcription factor activity;
I-kappaB kinase/NF-kappaB cascade;
cytosol;
protein binding;
plasma membrane;
|
ARRB1 |
6 |
positive regulation of transcription from RNA polymerase II promoter;
Notch signaling pathway;
cellular membrane organization;
cytosol;
protein binding;
plasma membrane;
|
GATA6 |
6 |
positive regulation of transcription from RNA polymerase II promoter;
cellular response to hypoxia;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
apoptotic process;
|
MAML1 |
6 |
positive regulation of transcription from RNA polymerase II promoter;
Notch signaling pathway;
gene expression;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
MED1 |
6 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
VEGFA |
6 |
positive regulation of transcription from RNA polymerase II promoter;
cellular response to hypoxia;
regulation of transcription from RNA polymerase II promoter in response to hypoxia;
cellular response to stress;
negative regulation of transcription from RNA polymerase II promoter;
protein binding;
|
YAP1 |
6 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
cytosol;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
TGFBR1 |
6 |
regulation of apoptotic process;
transforming growth factor beta receptor signaling pathway;
negative regulation of transforming growth factor beta receptor signaling pathway;
protein binding;
apoptotic process;
plasma membrane;
|
BIRC2 |
6 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
protein polyubiquitination;
cytosol;
protein binding;
apoptotic process;
transcription, DNA-dependent;
|
PAK1 |
6 |
T cell receptor signaling pathway;
cellular response to stress;
cytosol;
protein binding;
apoptotic process;
plasma membrane;
|
ADRBK1 |
6 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
PRKAR2B |
6 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
mitotic cell cycle;
cytosol;
plasma membrane;
|
CBL |
6 |
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
negative regulation of epidermal growth factor receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
CNOT6 |
6 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
transcription, DNA-dependent;
|
POLR2G |
6 |
gene expression;
viral reproduction;
nucleoplasm;
apoptotic process;
transcription initiation from RNA polymerase II promoter;
DNA repair;
|
RPL13 |
6 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
RPL14 |
6 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
RPS3 |
6 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
RPS9 |
6 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
SMC1A |
6 |
gene expression;
cell cycle checkpoint;
mitotic cell cycle;
nucleoplasm;
protein binding;
DNA repair;
|
SMG1 |
6 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
DNA repair;
|
CAMK2D |
6 |
cytokine-mediated signaling pathway;
endocytic vesicle membrane;
G1/S transition of mitotic cell cycle;
cytosol;
nucleoplasm;
plasma membrane;
|
POLE |
6 |
mitotic cell cycle;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
DNA repair;
|
CYBA |
5 |
innate immune response;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
|
HERC5 |
5 |
innate immune response;
cytokine-mediated signaling pathway;
negative regulation of type I interferon production;
cytosol;
protein binding;
|
MAVS |
5 |
innate immune response;
positive regulation of transcription from RNA polymerase II promoter;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
negative regulation of type I interferon production;
protein binding;
|
PYCARD |
5 |
innate immune response;
positive regulation of NF-kappaB transcription factor activity;
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;
cytosol;
protein binding;
|
TAX1BP1 |
5 |
innate immune response;
negative regulation of type I interferon production;
cytosol;
protein binding;
apoptotic process;
|
UBE2L6 |
5 |
innate immune response;
cytokine-mediated signaling pathway;
negative regulation of type I interferon production;
cytosol;
protein binding;
|
ESRRA |
5 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
KAT5 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
negative regulation of transcription from RNA polymerase II promoter;
cytosol;
protein binding;
transcription, DNA-dependent;
|
KDM1A |
5 |
positive regulation of transcription from RNA polymerase II promoter;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
|
MAML2 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
Notch signaling pathway;
gene expression;
nucleoplasm;
transcription initiation from RNA polymerase II promoter;
|
MCF2L |
5 |
positive regulation of transcription from RNA polymerase II promoter;
nerve growth factor receptor signaling pathway;
cytosol;
apoptotic process;
plasma membrane;
|
MYB |
5 |
positive regulation of transcription from RNA polymerase II promoter;
negative regulation of transcription from RNA polymerase II promoter;
G1/S transition of mitotic cell cycle;
protein binding;
transcription, DNA-dependent;
|
NCK1 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
T cell receptor signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
NCOA6 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
DNA repair;
|
NR5A1 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
RORA |
5 |
positive regulation of transcription from RNA polymerase II promoter;
gene expression;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
STRN3 |
5 |
positive regulation of transcription from RNA polymerase II promoter;
negative regulation of transcription from RNA polymerase II promoter;
nucleoplasm;
protein binding;
plasma membrane;
|
WWOX |
5 |
positive regulation of transcription from RNA polymerase II promoter;
cytosol;
protein binding;
apoptotic process;
plasma membrane;
|
RTN4 |
5 |
regulation of apoptotic process;
nerve growth factor receptor signaling pathway;
protein binding;
apoptotic process;
plasma membrane;
|
TRAF1 |
5 |
regulation of apoptotic process;
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
protein binding;
apoptotic process;
|
EEF1D |
5 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
gene expression;
cytosol;
protein binding;
transcription, DNA-dependent;
|
GJA1 |
5 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
cellular membrane organization;
protein binding;
apoptotic process;
plasma membrane;
|
NUP62 |
5 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
viral reproduction;
cytokine-mediated signaling pathway;
protein binding;
transcription, DNA-dependent;
|
RNF31 |
5 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
T cell receptor signaling pathway;
positive regulation of NF-kappaB transcription factor activity;
protein polyubiquitination;
protein binding;
|
TERF2IP |
5 |
positive regulation of I-kappaB kinase/NF-kappaB cascade;
positive regulation of NF-kappaB transcription factor activity;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
|
ARHGEF2 |
5 |
positive regulation of NF-kappaB transcription factor activity;
nerve growth factor receptor signaling pathway;
cytosol;
protein binding;
apoptotic process;
|
VPS37C |
5 |
egress of virus within host cell;
endosome membrane;
viral reproduction;
cellular membrane organization;
endosomal transport;
|
VPS37D |
5 |
egress of virus within host cell;
endosome membrane;
viral reproduction;
cellular membrane organization;
endosomal transport;
|
ADAM17 |
5 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
Notch signaling pathway;
protein binding;
plasma membrane;
|
ADCY4 |
5 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
protein binding;
plasma membrane;
|
FURIN |
5 |
nerve growth factor receptor signaling pathway;
transforming growth factor beta receptor signaling pathway;
Notch signaling pathway;
protease binding;
plasma membrane;
|
MAPKAP1 |
5 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytosol;
plasma membrane;
|
RICTOR |
5 |
nerve growth factor receptor signaling pathway;
epidermal growth factor receptor signaling pathway;
fibroblast growth factor receptor signaling pathway;
cytosol;
protein binding;
|
PRKAA1 |
5 |
cellular response to hypoxia;
activation of MAPK activity;
cytosol;
protein binding;
transcription, DNA-dependent;
|
ERBB2 |
5 |
epidermal growth factor receptor signaling pathway;
endosome membrane;
protein binding;
transcription, DNA-dependent;
plasma membrane;
|
PLCE1 |
5 |
epidermal growth factor receptor signaling pathway;
activation of MAPK activity;
cytosol;
protein binding;
plasma membrane;
|
ARRB2 |
5 |
transforming growth factor beta receptor signaling pathway;
Notch signaling pathway;
cytosol;
protein binding;
plasma membrane;
|
CTGF |
5 |
fibroblast growth factor receptor signaling pathway;
gene expression;
cytosol;
transcription initiation from RNA polymerase II promoter;
plasma membrane;
|
CLNS1A |
5 |
gene expression;
RNA metabolic process;
cytosol;
protein binding;
plasma membrane;
|
DCPS |
5 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
DDX6 |
5 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
FAU |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
GTF2H3 |
5 |
gene expression;
viral reproduction;
nucleoplasm;
transcription initiation from RNA polymerase II promoter;
DNA repair;
|
LSM4 |
5 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
PATL1 |
5 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
RAN |
5 |
gene expression;
viral reproduction;
cytosol;
nucleoplasm;
protein binding;
|
RPL12 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPL35 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPL37 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPL37A |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPL38 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPS12 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPS15A |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
RPS25 |
5 |
gene expression;
viral reproduction;
RNA metabolic process;
mRNA metabolic process;
cytosol;
|
SEC61B |
5 |
gene expression;
antigen processing and presentation of exogenous peptide antigen via MHC class I;
protein binding;
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;
antigen processing and presentation of peptide antigen via MHC class I;
|
SMG7 |
5 |
gene expression;
RNA metabolic process;
mRNA metabolic process;
cytosol;
protein binding;
|
SNRPB |
5 |
gene expression;
RNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
SNRPD1 |
5 |
gene expression;
RNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
SNRPD2 |
5 |
gene expression;
RNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
SNRPD3 |
5 |
gene expression;
RNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
SNRPG |
5 |
gene expression;
RNA metabolic process;
cytosol;
nucleoplasm;
protein binding;
|
SSRP1 |
5 |
gene expression;
viral reproduction;
nucleoplasm;
protein binding;
DNA repair;
|
TAF10 |
5 |
gene expression;
viral reproduction;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
TAF13 |
5 |
gene expression;
viral reproduction;
nucleoplasm;
protein binding;
transcription initiation from RNA polymerase II promoter;
|
CUL5 |
5 |
viral reproduction;
G1/S transition of mitotic cell cycle;
cytosol;
protein binding;
plasma membrane;
|
HMGA1 |
5 |
viral reproduction;
cytosol;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
|
XRCC5 |
5 |
viral reproduction;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
DNA repair;
|
PTTG1 |
5 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
mitotic cell cycle;
cytosol;
protein binding;
DNA repair;
|
WASL |
5 |
endocytic vesicle membrane;
cytosol;
protein binding;
transcription, DNA-dependent;
plasma membrane;
|
ATM |
5 |
cell cycle checkpoint;
nucleoplasm;
protein binding;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
DNA repair;
|
CHEK1 |
5 |
cell cycle checkpoint;
cytosol;
nucleoplasm;
protein binding;
DNA repair;
|
RBBP8 |
5 |
cell cycle checkpoint;
negative regulation of transcription from RNA polymerase II promoter;
G1/S transition of mitotic cell cycle;
protein binding;
DNA repair;
|
RFWD2 |
5 |
cell cycle checkpoint;
cytosol;
nucleoplasm;
protein binding;
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
|
FEN1 |
5 |
mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
protein binding;
DNA repair;
|
POLA2 |
5 |
mitotic cell cycle;
M/G1 transition of mitotic cell cycle;
G1/S transition of mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
|
POLD3 |
5 |
mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
protein binding;
DNA repair;
|
POLD4 |
5 |
mitotic cell cycle;
S phase of mitotic cell cycle;
nucleoplasm;
protein binding;
DNA repair;
|
RRM2 |
5 |
mitotic cell cycle;
G1/S transition of mitotic cell cycle;
cytosol;
nucleoplasm;
protein binding;
|
HINFP |
5 |
G1/S transition of mitotic cell cycle;
nucleoplasm;
protein binding;
transcription, DNA-dependent;
DNA repair;
|