ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0050852
Name T cell receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  24
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 24)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 6p21.3 2(1/1/0) TAS

Genes from other sources Help (count: 23)

Approved Symbol Approved Name Source Evidence[PMID]
UBB ubiquitin B Mapped by significant region TAS
FYB FYN binding protein Mapped by significant region TAS
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region TAS
RNF31 ring finger protein 31 Mapped by significant region IDA
UBC ubiquitin C Mapped by CNV TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region NAS[9295052]
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 Mapped by CNV TAS
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region ISS
CACNB3 calcium channel, voltage-dependent, beta 3 subunit Mapped by PBA pathway IEA
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region TAS
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
NCK1 NCK adaptor protein 1 Mapped by PBA pathway TAS
ITK IL2-inducible T-cell kinase Mapped by significant region ISS; TAS
CD3E CD3e molecule, epsilon (CD3-TCR complex) Mapped by significant region TAS
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 Mapped by CNV TAS
CD3G CD3g molecule, gamma (CD3-TCR complex) Mapped by significant region TAS
THY1 Thy-1 cell surface antigen Mapped by significant region ISS
CD3D CD3d molecule, delta (CD3-TCR complex) Mapped by significant region TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
THEMIS thymocyte selection associated Mapped by significant region ISS
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IDA[15125833]; TAS
CACNB4 calcium channel, voltage-dependent, beta 4 subunit Mapped by PBA pathway IEA