ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RELA
Previous Symbol	NFKB3
Symbol Alias	p65
Approved Name	v-rel avian reticuloendotheliosis viral oncogene homolog A
Previous Name	"nuclear factor of kappa light polypeptide gene enhancer in B-cells 3"
Location	11q13
Position	chr11:65421067-65430565, -1
External Links	HGNC: 9955 Entrez Gene: 5970 Ensembl: ENSG00000173039 UCSC: uc001ofg.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 77)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 77)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	molecular function	IDA[3091258]	17
GO:0033613	activating transcription factor binding	molecular function	IPI[15489227]	2
GO:0005515	protein binding	molecular function	IPI	1015
GO:0034142	toll-like receptor 4 signaling pathway	biological process	TAS	11
GO:0045084	positive regulation of interleukin-12 biosynthetic process	biological process	IEA	2
GO:0009612	response to mechanical stimulus	biological process	IEA	10
GO:0003677	DNA binding	molecular function	IDA[15790681]	257
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0032570	response to progesterone stimulus	biological process	IEA	7
GO:0051092	positive regulation of NF-kappaB transcription factor activity	biological process	IDA[15790681]; TAS	27
GO:0044212	transcription regulatory region DNA binding	molecular function	IDA[17350185]	28
GO:0009887	organ morphogenesis	biological process	IEA	19
GO:0045087	innate immune response	biological process	TAS	57
GO:0005634	nucleus	cellular component	IDA[15790681]	877
GO:0051607	defense response to virus	biological process	NAS[8717528]	16
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	biological process	IEP[12761501]	28
GO:0043200	response to amino acid stimulus	biological process	IEA	7
GO:0019221	cytokine-mediated signaling pathway	biological process	IDA[15876188]	33
GO:0071356	cellular response to tumor necrosis factor	biological process	IDA[18073330]	9
GO:0003682	chromatin binding	molecular function	IDA[19058135]	50
GO:0046627	negative regulation of insulin receptor signaling pathway	biological process	IEA	5
GO:0042802	identical protein binding	molecular function	IDA[9437432]; IPI[10498867]	77
GO:0007568	aging	biological process	IEA	29
GO:0031293	membrane protein intracellular domain proteolysis	biological process	TAS	2
GO:0032403	protein complex binding	molecular function	IEA	30
GO:0071532	ankyrin repeat binding	molecular function	IEA	1
GO:0048011	nerve growth factor receptor signaling pathway	biological process	TAS	51
GO:0034134	toll-like receptor 2 signaling pathway	biological process	TAS	10
GO:0071347	cellular response to interleukin-1	biological process	IDA[18073330]	3
GO:0042493	response to drug	biological process	IEA	73
GO:0001942	hair follicle development	biological process	IEA	4
GO:0019048	virus-host interaction	biological process	IEA	61
GO:0034130	toll-like receptor 1 signaling pathway	biological process	TAS	10
GO:0051591	response to cAMP	biological process	IEA	12
GO:0008134	transcription factor binding	molecular function	IPI[10849440]	44
GO:0006117	acetaldehyde metabolic process	biological process	IEA	1
GO:0050852	T cell receptor signaling pathway	biological process	TAS	24
GO:0008284	positive regulation of cell proliferation	biological process	IEA	75
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological process	IDA[17350185]; IMP	141
GO:0033590	response to cobalamin	biological process	IEA	1
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IDA[12048232]	148
GO:0005737	cytoplasm	cellular component	IDA[15790681]	781
GO:0043278	response to morphine	biological process	IEA	9
GO:0043565	sequence-specific DNA binding	molecular function	IEA	80
GO:0002224	toll-like receptor signaling pathway	biological process	TAS	10
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	biological process	IDA[12527755]	1
GO:0006968	cellular defense response	biological process	NAS[8717528]	12
GO:0005667	transcription factor complex	cellular component	IDA[12048232]	52
GO:0071222	cellular response to lipopolysaccharide	biological process	IEA	15
GO:0032868	response to insulin stimulus	biological process	IEA	11
GO:0002756	MyD88-independent toll-like receptor signaling pathway	biological process	TAS	9
GO:0014040	positive regulation of Schwann cell differentiation	biological process	IEA	1
GO:0008063	Toll signaling pathway	biological process	TAS	11
GO:0031625	ubiquitin protein ligase binding	molecular function	IPI[12748188]	30
GO:0047485	protein N-terminus binding	molecular function	IPI[7739562]	27
GO:0051059	NF-kappaB binding	molecular function	IPI[8441377]	8
GO:0001889	liver development	biological process	IEA	16
GO:0019901	protein kinase binding	molecular function	IPI[15465828]	59
GO:0042542	response to hydrogen peroxide	biological process	IEA	7
GO:0006954	inflammatory response	biological process	IDA[12924514]	54
GO:0005829	cytosol	cellular component	TAS	485
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	biological process	TAS	10
GO:0010033	response to organic substance	biological process	IDA[10747850]	4
GO:0043066	negative regulation of apoptotic process	biological process	IDA[10747850]; IMP	85
GO:0032332	positive regulation of chondrocyte differentiation	biological process	IEA	3
GO:0032495	response to muramyl dipeptide	biological process	IEA	2
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	biological process	TAS	10
GO:0045893	positive regulation of transcription, DNA-dependent	biological process	IDA[18073330]	89
GO:0042177	negative regulation of protein catabolic process	biological process	IEA	5
GO:0045892	negative regulation of transcription, DNA-dependent	biological process	IDA[17350185]	77
GO:0032481	positive regulation of type I interferon production	biological process	TAS	2
GO:0050727	regulation of inflammatory response	biological process	ISS	9
GO:0070555	response to interleukin-1	biological process	IGI[15489227]	6
GO:0034138	toll-like receptor 3 signaling pathway	biological process	TAS	11
GO:0010224	response to UV-B	biological process	IDA[15616591]	2
GO:0070491	repressing transcription factor binding	molecular function	IPI[10660609]	3
GO:0042301	phosphate ion binding	molecular function	IDA[10521409]	3

Gene related KEGG pathways (count: 9)

ID	Name	No. of Genes in ADHDgene
hsa05222	Small cell lung cancer	17
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	14
hsa05220	Chronic myeloid leukemia	12
hsa05221	Acute myeloid leukemia	10
hsa04210	Apoptosis	13
hsa04620	Toll-like receptor signaling pathway	14
hsa05215	Prostate cancer	16
hsa05212	Pancreatic cancer	13
hsa04920	Adipocytokine signaling pathway	9

Genes shared at least 5 GO terms with RELA (count: 261)

Gene Symbol	Pathway Count	Pathway List
MAPK1	23	protein binding; toll-like receptor 4 signaling pathway; DNA binding; nucleoplasm; organ morphogenesis; innate immune response; nucleus; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; virus-host interaction; toll-like receptor 1 signaling pathway; transcription factor binding; T cell receptor signaling pathway; positive regulation of cell proliferation; cytoplasm; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; positive regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway;
MAPK9	20	protein binding; toll-like receptor 4 signaling pathway; response to mechanical stimulus; nucleoplasm; innate immune response; cellular response to tumor necrosis factor; toll-like receptor 2 signaling pathway; cellular response to interleukin-1; response to drug; toll-like receptor 1 signaling pathway; transcription factor binding; toll-like receptor signaling pathway; cellular response to lipopolysaccharide; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; positive regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway;
MAPK3	19	protein binding; toll-like receptor 4 signaling pathway; nucleoplasm; organ morphogenesis; innate immune response; nucleus; cytokine-mediated signaling pathway; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; virus-host interaction; toll-like receptor 1 signaling pathway; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway;
UBC	19	protein binding; toll-like receptor 4 signaling pathway; nucleoplasm; positive regulation of NF-kappaB transcription factor activity; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytokine-mediated signaling pathway; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway;
UBB	19	protein binding; toll-like receptor 4 signaling pathway; nucleoplasm; positive regulation of NF-kappaB transcription factor activity; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytokine-mediated signaling pathway; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway;
MAPK7	17	protein binding; toll-like receptor 4 signaling pathway; nucleoplasm; innate immune response; nucleus; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; negative regulation of apoptotic process; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway;
TLR4	16	protein binding; toll-like receptor 4 signaling pathway; positive regulation of interleukin-12 biosynthetic process; positive regulation of NF-kappaB transcription factor activity; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; toll-like receptor signaling pathway; cellular response to lipopolysaccharide; Toll signaling pathway; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway;
MAP2K3	16	protein binding; toll-like receptor 4 signaling pathway; nucleoplasm; innate immune response; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; protein kinase binding; inflammatory response; cytosol; TRIF-dependent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; positive regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway;
GATA6	15	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; chromatin binding; response to drug; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; liver development; protein kinase binding; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent;
IRF7	15	protein binding; toll-like receptor 4 signaling pathway; DNA binding; nucleoplasm; innate immune response; nucleus; cytokine-mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; cytosol; TRIF-dependent toll-like receptor signaling pathway; positive regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway;
GSK3B	13	protein binding; organ morphogenesis; nucleus; nerve growth factor receptor signaling pathway; response to drug; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; ubiquitin protein ligase binding; NF-kappaB binding; protein kinase binding; cytosol; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent;
SREBF1	13	protein binding; DNA binding; response to progesterone stimulus; nucleus; chromatin binding; aging; protein complex binding; response to drug; response to cAMP; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; protein kinase binding;
IL6	13	response to mechanical stimulus; positive regulation of NF-kappaB transcription factor activity; defense response to virus; response to amino acid stimulus; cytokine-mediated signaling pathway; aging; response to drug; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to insulin stimulus; inflammatory response; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent;
ETS1	12	protein binding; response to mechanical stimulus; DNA binding; nucleus; transcription factor binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex; positive regulation of transcription, DNA-dependent; response to interleukin-1;
HNF1B	11	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; DNA binding; transcription regulatory region DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent;
KDM1A	11	protein binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent;
HMGA1	11	protein binding; DNA binding; nucleoplasm; nucleus; virus-host interaction; transcription factor binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; cytosol; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
PYCARD	11	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleus; defense response to virus; cellular response to tumor necrosis factor; cellular response to interleukin-1; cytoplasm; cellular response to lipopolysaccharide; inflammatory response; cytosol;
HES1	11	protein binding; DNA binding; nucleus; transcription factor binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; liver development; negative regulation of transcription, DNA-dependent;
CREBBP	11	protein binding; nucleoplasm; innate immune response; nucleus; chromatin binding; virus-host interaction; transcription factor binding; sequence-specific DNA binding transcription factor activity; cytoplasm; transcription factor complex; positive regulation of transcription, DNA-dependent;
TIRAP	11	protein binding; toll-like receptor 4 signaling pathway; positive regulation of NF-kappaB transcription factor activity; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; toll-like receptor signaling pathway; Toll signaling pathway; inflammatory response; MyD88-dependent toll-like receptor signaling pathway;
YAP1	11	protein binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; chromatin binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; transcription factor complex; cytosol; negative regulation of apoptotic process;
MEN1	11	protein binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; sequence-specific DNA binding; protein N-terminus binding; cytosol; negative regulation of transcription, DNA-dependent;
FOSL1	11	protein binding; response to mechanical stimulus; response to progesterone stimulus; nucleus; response to drug; response to cAMP; positive regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; cellular defense response; response to hydrogen peroxide; cytosol;
FOXC2	10	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent;
FOXE1	10	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
FOXG1	10	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; DNA binding; nucleus; aging; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription factor complex; negative regulation of transcription, DNA-dependent;
CIITA	10	activating transcription factor binding; protein binding; DNA binding; nucleoplasm; transcription regulatory region DNA binding; cytokine-mediated signaling pathway; protein complex binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
TFAP2B	10	protein binding; DNA binding; nucleus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
TNFAIP3	10	protein binding; DNA binding; innate immune response; nucleus; cytoplasm; cellular response to lipopolysaccharide; inflammatory response; cytosol; negative regulation of apoptotic process; response to muramyl dipeptide;
SNCA	10	protein binding; nucleus; identical protein binding; aging; response to drug; cytoplasm; protein N-terminus binding; cytosol; negative regulation of apoptotic process; response to interleukin-1;
KAT5	10	protein binding; nucleus; protein complex binding; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; cytosol; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; repressing transcription factor binding;
PRKD1	10	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; identical protein binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; inflammatory response; cytosol;
FOXP2	9	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; DNA binding; chromatin binding; transcription factor binding; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; transcription factor complex; negative regulation of transcription, DNA-dependent;
FOXF1	9	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; DNA binding; transcription regulatory region DNA binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription factor complex; positive regulation of transcription, DNA-dependent;
TFAP4	9	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; DNA binding; transcription regulatory region DNA binding; nucleus; sequence-specific DNA binding; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
FOXP1	9	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; nucleus; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; sequence-specific DNA binding; transcription factor complex; negative regulation of transcription, DNA-dependent;
TRIM5	9	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleus; defense response to virus; positive regulation of I-kappaB kinase/NF-kappaB cascade; identical protein binding; virus-host interaction; cytoplasm;
BAD	9	protein binding; response to progesterone stimulus; response to amino acid stimulus; cytokine-mediated signaling pathway; nerve growth factor receptor signaling pathway; response to drug; protein kinase binding; response to hydrogen peroxide; cytosol;
MALT1	9	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; T cell receptor signaling pathway; cytoplasm; cytosol; negative regulation of apoptotic process;
HINFP	9	protein binding; DNA binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; chromatin binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
TLE1	9	protein binding; nucleoplasm; organ morphogenesis; nucleus; chromatin binding; transcription factor binding; transcription factor complex; cytosol; negative regulation of transcription, DNA-dependent;
DAXX	9	protein binding; nucleus; virus-host interaction; transcription factor binding; cytoplasm; ubiquitin protein ligase binding; protein N-terminus binding; cytosol; negative regulation of transcription, DNA-dependent;
MED1	9	protein binding; nucleoplasm; nucleus; chromatin binding; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; liver development; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent;
XRCC5	9	protein binding; DNA binding; nucleoplasm; transcription regulatory region DNA binding; nucleus; cytoplasm; ubiquitin protein ligase binding; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent;
SOX8	9	DNA binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
NR5A1	8	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; DNA binding; nucleoplasm; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding;
FOXL1	8	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; DNA binding; organ morphogenesis; nucleus; transcription factor binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex;
RBPJ	8	protein binding; DNA binding; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of transcription, DNA-dependent;
FADD	8	protein binding; innate immune response; defense response to virus; positive regulation of I-kappaB kinase/NF-kappaB cascade; identical protein binding; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter; cytosol;
MTA2	8	protein binding; transcription regulatory region DNA binding; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex;
ATXN1	8	protein binding; DNA binding; nucleoplasm; nucleus; identical protein binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; negative regulation of transcription, DNA-dependent;
NCF2	8	protein binding; response to progesterone stimulus; innate immune response; aging; response to drug; cytoplasm; cellular defense response; cytosol;
CCND1	8	protein binding; nucleoplasm; nucleus; protein complex binding; response to drug; liver development; protein kinase binding; cytosol;
IRF9	8	protein binding; nucleoplasm; nucleus; defense response to virus; cytokine-mediated signaling pathway; sequence-specific DNA binding transcription factor activity; cytoplasm; cytosol;
ARRB1	8	protein binding; transcription regulatory region DNA binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; ubiquitin protein ligase binding; cytosol;
DNAJA3	8	protein binding; nucleus; transcription factor binding; cytoplasm; NF-kappaB binding; protein kinase binding; cytosol; negative regulation of apoptotic process;
HEY2	8	protein binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
BNIP3	8	protein binding; nucleoplasm; nucleus; defense response to virus; identical protein binding; virus-host interaction; cytoplasm; negative regulation of apoptotic process;
STRN3	8	protein binding; nucleoplasm; nucleus; protein complex binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of transcription, DNA-dependent;
AXIN1	8	protein binding; nucleus; identical protein binding; cytoplasm; ubiquitin protein ligase binding; protein kinase binding; cytosol; positive regulation of transcription, DNA-dependent;
FOXD4	7	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor complex;
IRF8	7	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; nucleus; cytokine-mediated signaling pathway; cellular response to lipopolysaccharide; cytosol; positive regulation of transcription, DNA-dependent;
PDPK1	7	protein binding; nucleoplasm; nerve growth factor receptor signaling pathway; T cell receptor signaling pathway; cytoplasm; protein kinase binding; cytosol;
PIK3R1	7	protein binding; nerve growth factor receptor signaling pathway; virus-host interaction; T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cytosol; negative regulation of apoptotic process;
HERC5	7	protein binding; innate immune response; nucleus; defense response to virus; cytokine-mediated signaling pathway; cytoplasm; cytosol;
AATF	7	protein binding; nucleus; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of apoptotic process;
MYB	7	protein binding; DNA binding; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
RAN	7	protein binding; nucleoplasm; chromatin binding; virus-host interaction; cytoplasm; cytosol; positive regulation of transcription, DNA-dependent;
KMT2A	7	protein binding; transcription regulatory region DNA binding; nucleus; identical protein binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent;
PARK2	7	protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; ubiquitin protein ligase binding; protein kinase binding; cytosol;
ZBTB16	7	protein binding; DNA binding; nucleus; identical protein binding; positive regulation of chondrocyte differentiation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
POU2F3	7	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; transcription factor complex;
ARHGEF2	7	protein binding; positive regulation of NF-kappaB transcription factor activity; cellular response to tumor necrosis factor; nerve growth factor receptor signaling pathway; transcription factor binding; cytosol; negative regulation of apoptotic process;
SQSTM1	7	protein binding; nucleoplasm; identical protein binding; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding; cytosol;
MAVS	7	protein binding; innate immune response; defense response to virus; positive regulation of I-kappaB kinase/NF-kappaB cascade; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding;
CDK5RAP2	7	protein binding; transcription regulatory region DNA binding; protein complex binding; cytoplasm; protein kinase binding; cytosol; positive regulation of transcription, DNA-dependent;
BIRC2	7	protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein N-terminus binding; cytosol; negative regulation of apoptotic process; regulation of inflammatory response;
NUP62	7	protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytokine-mediated signaling pathway; chromatin binding; cytoplasm; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent;
SLC6A3	7	protein binding; aging; protein complex binding; response to drug; response to cAMP; cytoplasm; protein N-terminus binding;
CRYAB	7	protein binding; nucleus; aging; cytoplasm; response to hydrogen peroxide; cytosol; negative regulation of apoptotic process;
NCOA6	7	protein binding; nucleoplasm; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; positive regulation of transcription, DNA-dependent;
APC	7	protein binding; nucleus; hair follicle development; cytoplasm; protein kinase binding; cytosol; negative regulation of apoptotic process;
SOCS1	7	protein binding; nucleus; cytokine-mediated signaling pathway; negative regulation of insulin receptor signaling pathway; cytoplasm; protein kinase binding; cytosol;
TBX1	7	DNA binding; nucleus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent;
SPI1	6	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
STK11	6	protein binding; nucleus; identical protein binding; protein complex binding; cytoplasm; cytosol;
TP53BP1	6	protein binding; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; positive regulation of transcription, DNA-dependent;
ID2	6	protein binding; nucleus; cytoplasm; cytosol; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
BCAR1	6	protein binding; nerve growth factor receptor signaling pathway; T cell receptor signaling pathway; cytoplasm; protein kinase binding; cytosol;
CCR5	6	protein binding; virus-host interaction; cytoplasm; cellular defense response; cellular response to lipopolysaccharide; inflammatory response;
HOXA5	6	protein binding; DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
SMARCD3	6	protein binding; nucleoplasm; nucleus; transcription factor binding; cytoplasm; positive regulation of transcription, DNA-dependent;
TERF2IP	6	protein binding; nucleoplasm; positive regulation of NF-kappaB transcription factor activity; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm;
PIK3CG	6	protein binding; innate immune response; cytoplasm; inflammatory response; cytosol; negative regulation of apoptotic process;
ILK	6	protein binding; positive regulation of cell proliferation; cytoplasm; protein kinase binding; cytosol; positive regulation of transcription, DNA-dependent;
APBB1	6	protein binding; nucleus; chromatin binding; transcription factor binding; cytoplasm; positive regulation of transcription, DNA-dependent;
UBE2I	6	protein binding; nucleus; virus-host interaction; transcription factor binding; cytoplasm; negative regulation of transcription, DNA-dependent;
SSRP1	6	protein binding; DNA binding; nucleoplasm; nucleus; chromatin binding; cytoplasm;
CREBZF	6	protein binding; DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
NR4A2	6	protein binding; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; sequence-specific DNA binding;
ADAM17	6	protein binding; membrane protein intracellular domain proteolysis; nerve growth factor receptor signaling pathway; response to drug; positive regulation of cell proliferation; cytoplasm;
UBE3A	6	protein binding; nucleus; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; cytosol;
SNW1	6	protein binding; nucleoplasm; nucleus; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
ESRRA	6	protein binding; DNA binding; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding;
RIPK3	6	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; identical protein binding; cytosol; positive regulation of type I interferon production;
IL12B	6	protein binding; defense response to virus; identical protein binding; cytoplasm; cellular response to lipopolysaccharide; response to UV-B;
PGR	6	protein binding; DNA binding; nucleoplasm; nucleus; cytoplasm; sequence-specific DNA binding;
GSTP1	6	protein binding; nucleus; cytoplasm; cellular response to lipopolysaccharide; cytosol; negative regulation of apoptotic process;
MKL2	6	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; liver development;
MEIS2	6	protein binding; nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
RPS3	6	protein binding; nucleus; cytoplasm; NF-kappaB binding; protein kinase binding; cytosol;
TRIM32	6	protein binding; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleus; cytoplasm; negative regulation of apoptotic process;
SYK	6	protein binding; organ morphogenesis; innate immune response; virus-host interaction; protein kinase binding; cytosol;
VEGFA	6	protein binding; identical protein binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; negative regulation of apoptotic process;
MAP2K5	6	protein binding; nucleus; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cytosol; negative regulation of apoptotic process;
ARRB2	6	protein binding; nucleus; protein complex binding; cytoplasm; ubiquitin protein ligase binding; cytosol;
NCK1	6	protein binding; nucleus; T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; cytosol;
INPPL1	6	protein binding; negative regulation of insulin receptor signaling pathway; response to drug; cytoplasm; response to insulin stimulus; cytosol;
ZNF24	6	protein binding; DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
XPO1	6	protein binding; nucleoplasm; response to drug; virus-host interaction; cytoplasm; cytosol;
NEDD4L	6	protein binding; nucleoplasm; nucleus; virus-host interaction; cytoplasm; cytosol;
E4F1	6	protein binding; DNA binding; nucleoplasm; virus-host interaction; sequence-specific DNA binding transcription factor activity; cytoplasm;
ZFPM1	6	protein binding; DNA binding; nucleoplasm; transcription factor binding; cytoplasm; transcription factor complex;
CBL	6	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; cytosol; negative regulation of apoptotic process;
PAK1	6	protein binding; identical protein binding; T cell receptor signaling pathway; cytoplasm; protein kinase binding; cytosol;
BIRC3	6	protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; negative regulation of apoptotic process; regulation of inflammatory response;
PRKAA1	6	protein binding; nucleus; chromatin binding; positive regulation of cell proliferation; cytosol; negative regulation of apoptotic process;
DDB1	6	protein binding; DNA binding; nucleoplasm; nucleus; virus-host interaction; cytoplasm;
CYBA	6	protein binding; innate immune response; cellular response to tumor necrosis factor; response to drug; inflammatory response; response to interleukin-1;
HOXA9	6	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; transcription factor complex;
PLK1	6	protein binding; nucleoplasm; nucleus; protein kinase binding; cytosol; negative regulation of apoptotic process;
USP7	6	protein binding; nucleus; virus-host interaction; transcription factor binding; ubiquitin protein ligase binding; cytosol;
PSMC3	6	protein binding; nucleoplasm; nucleus; virus-host interaction; cytoplasm; cytosol;
RPS6KA4	6	protein binding; positive regulation of NF-kappaB transcription factor activity; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; inflammatory response;
ATM	6	protein binding; DNA binding; nucleoplasm; protein complex binding; protein N-terminus binding; negative regulation of apoptotic process;
NCOR2	6	protein binding; DNA binding; nucleoplasm; nucleus; chromatin binding; protein N-terminus binding;
RREB1	6	DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
NFATC4	6	DNA binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; transcription factor complex; inflammatory response; cytosol;
HOXB1	6	DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding;
ETV5	6	DNA binding; transcription regulatory region DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent;
HOXA13	6	DNA binding; transcription regulatory region DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
TAF4B	6	DNA binding; nucleoplasm; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; NF-kappaB binding;
IKZF1	6	DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding;
TLR9	6	positive regulation of NF-kappaB transcription factor activity; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; inflammatory response;
GLIS2	6	transcription regulatory region DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
KLF4	6	transcription regulatory region DNA binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
TFEB	6	transcription regulatory region DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; transcription factor complex;
LHX1	6	organ morphogenesis; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
ONECUT2	6	organ morphogenesis; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; liver development;
MTA3	6	nucleus; chromatin binding; positive regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding;
HOXA7	6	nucleus; transcription factor binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
BSX	6	nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; transcription factor complex;
ISL1	6	nucleus; chromatin binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm;
ARG1	6	response to amino acid stimulus; response to drug; cytoplasm; cellular response to lipopolysaccharide; liver development; cytosol;
HOXA11	6	sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding; transcription factor complex; positive regulation of chondrocyte differentiation; positive regulation of transcription, DNA-dependent;
TLE4	5	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; nucleoplasm; nucleus; chromatin binding; repressing transcription factor binding;
GATAD2A	5	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; negative regulation of transcription, DNA-dependent;
PRC1	5	protein binding; nucleus; identical protein binding; cytoplasm; protein kinase binding;
TRAF1	5	protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; ubiquitin protein ligase binding;
PALB2	5	protein binding; DNA binding; nucleoplasm; organ morphogenesis; negative regulation of apoptotic process;
MAML1	5	protein binding; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding;
GREM1	5	protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent;
NIPBL	5	protein binding; nucleus; chromatin binding; protein N-terminus binding; negative regulation of transcription, DNA-dependent;
GEMIN2	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
EREG	5	protein binding; organ morphogenesis; cytokine-mediated signaling pathway; positive regulation of cell proliferation; negative regulation of transcription, DNA-dependent;
CHP2	5	protein binding; nucleus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; cytoplasm;
TSC1	5	protein binding; cytoplasm; response to insulin stimulus; protein N-terminus binding; cytosol;
MIF	5	protein binding; innate immune response; cytoplasm; inflammatory response; negative regulation of apoptotic process;
TNFRSF11A	5	protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cell proliferation; response to interleukin-1;
RNF31	5	protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; T cell receptor signaling pathway; cytoplasm;
RCC1	5	protein binding; nucleoplasm; nucleus; chromatin binding; cytoplasm;
MAP1S	5	protein binding; DNA binding; nucleus; identical protein binding; cytosol;
PRPF19	5	protein binding; DNA binding; nucleus; identical protein binding; cytoplasm;
PAFAH1B1	5	protein binding; nucleus; protein complex binding; cytoplasm; cytosol;
CUL5	5	protein binding; nucleus; virus-host interaction; ubiquitin protein ligase binding; cytosol;
BRMS1	5	protein binding; nucleus; cytoplasm; NF-kappaB binding; negative regulation of transcription, DNA-dependent;
BASP1	5	protein binding; transcription regulatory region DNA binding; nucleus; cytoplasm; negative regulation of transcription, DNA-dependent;
CREB5	5	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent;
NEK6	5	protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; protein kinase binding;
CBFA2T3	5	protein binding; nucleoplasm; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity;
HSPA8	5	protein binding; nucleus; virus-host interaction; cytosol; negative regulation of transcription, DNA-dependent;
BAIAP2	5	protein binding; nucleus; identical protein binding; cytoplasm; cytosol;
FYB	5	protein binding; nucleus; protein complex binding; T cell receptor signaling pathway; cytosol;
RNPS1	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
NCBP1	5	protein binding; DNA binding; nucleoplasm; nucleus; cytosol;
DHX9	5	protein binding; DNA binding; nucleoplasm; nucleus; cytoplasm;
RAD9A	5	protein binding; nucleoplasm; nucleus; cytoplasm; protein kinase binding;
RORA	5	protein binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
TAF10	5	protein binding; nucleoplasm; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm;
SART1	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
ZNF423	5	protein binding; DNA binding; nucleus; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
EED	5	protein binding; nucleus; chromatin binding; identical protein binding; negative regulation of transcription, DNA-dependent;
SMARCB1	5	protein binding; nucleoplasm; nucleus; virus-host interaction; positive regulation of transcription from RNA polymerase II promoter;
ATG5	5	protein binding; innate immune response; response to drug; cytoplasm; negative regulation of apoptotic process;
TSC2	5	protein binding; nucleus; nerve growth factor receptor signaling pathway; cytoplasm; cytosol;
AIP	5	protein binding; nucleus; transcription factor binding; cytoplasm; cytosol;
TCF25	5	protein binding; DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm;
TH	5	protein binding; organ morphogenesis; nucleus; cytoplasm; cytosol;
SMC3	5	protein binding; nucleoplasm; nucleus; chromatin binding; cytoplasm;
PKD1	5	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; protein kinase binding;
MAP3K5	5	protein binding; innate immune response; identical protein binding; virus-host interaction; protein kinase binding;
TCEB1	5	protein binding; nucleoplasm; protein complex binding; virus-host interaction; cytosol;
UBN1	5	protein binding; DNA binding; nucleus; virus-host interaction; sequence-specific DNA binding transcription factor activity;
TAF13	5	protein binding; DNA binding; nucleoplasm; nucleus; sequence-specific DNA binding transcription factor activity;
HOXA1	5	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
DAB2	5	protein binding; nucleus; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
BCLAF1	5	protein binding; DNA binding; nucleus; cytoplasm; negative regulation of transcription, DNA-dependent;
RSF1	5	protein binding; nucleoplasm; nucleus; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
FLT4	5	protein binding; nucleus; positive regulation of cell proliferation; cytoplasm; negative regulation of apoptotic process;
BANF1	5	protein binding; DNA binding; nucleoplasm; virus-host interaction; cytosol;
DEAF1	5	protein binding; DNA binding; nucleus; cytoplasm; transcription factor complex;
PARN	5	protein binding; nucleus; cytoplasm; protein kinase binding; cytosol;
KAT8	5	protein binding; nucleus; transcription factor binding; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
TJP1	5	protein binding; nucleus; response to drug; cytoplasm; cytosol;
CDT1	5	protein binding; DNA binding; nucleoplasm; nucleus; cytosol;
WWOX	5	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; cytosol;
GRB10	5	protein binding; negative regulation of insulin receptor signaling pathway; cytoplasm; response to insulin stimulus; cytosol;
NUMA1	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
ATF6	5	protein binding; nucleoplasm; nucleus; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
BLMH	5	protein binding; nucleus; response to drug; cytoplasm; cytosol;
FUS	5	protein binding; DNA binding; nucleoplasm; nucleus; cytoplasm;
SMC1A	5	protein binding; nucleoplasm; nucleus; chromatin binding; cytoplasm;
PTTG1	5	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; cytosol;
RNF20	5	protein binding; nucleus; chromatin binding; ubiquitin protein ligase binding; positive regulation of transcription, DNA-dependent;
FANCC	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
NPAT	5	protein binding; nucleus; sequence-specific DNA binding transcription factor activity; protein N-terminus binding; positive regulation of transcription, DNA-dependent;
CFL1	5	protein binding; nucleus; response to amino acid stimulus; cytoplasm; negative regulation of apoptotic process;
IGHMBP2	5	protein binding; DNA binding; nucleus; transcription factor binding; cytoplasm;
RNF40	5	protein binding; nucleus; protein complex binding; cytoplasm; ubiquitin protein ligase binding;
EGLN3	5	protein binding; nucleoplasm; nucleus; cytoplasm; cytosol;
INS	5	protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of cell proliferation; negative regulation of apoptotic process; negative regulation of protein catabolic process;
RPTOR	5	protein binding; protein complex binding; cytoplasm; protein kinase binding; cytosol;
ADORA2A	5	protein binding; nerve growth factor receptor signaling pathway; response to drug; cellular defense response; inflammatory response;
PDCD4	5	protein binding; nucleus; cytoplasm; cytosol; negative regulation of transcription, DNA-dependent;
DRD3	5	protein binding; response to drug; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to morphine;
FLCN	5	protein binding; nucleus; protein complex binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm;
GHR	5	protein binding; nucleus; response to morphine; protein kinase binding; response to interleukin-1;
PDCD10	5	protein binding; positive regulation of cell proliferation; protein N-terminus binding; cytosol; negative regulation of apoptotic process;
EEF1D	5	protein binding; DNA binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytosol;
BARX2	5	DNA binding; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex;
PKNOX2	5	DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding;
OASL	5	DNA binding; defense response to virus; cytokine-mediated signaling pathway; cytoplasm; cytosol;
ZNF263	5	DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of transcription, DNA-dependent;
NPAS2	5	DNA binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; cytosol;
DRAP1	5	DNA binding; nucleus; transcription factor binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding;
ARID3C	5	DNA binding; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; cytoplasm;
RCOR2	5	DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; negative regulation of transcription, DNA-dependent;
MED12	5	nucleoplasm; nucleus; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent;
MED17	5	nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; positive regulation of transcription, DNA-dependent;
WNT11	5	transcription regulatory region DNA binding; cytoplasm; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent;
ZNF174	5	transcription regulatory region DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; cytoplasm; negative regulation of transcription, DNA-dependent;
HMGCS1	5	nucleus; response to drug; cytoplasm; liver development; cytosol;
LPIN1	5	nucleus; positive regulation of transcription from RNA polymerase II promoter; cytoplasm; transcription factor complex; cytosol;
MAF	5	nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; sequence-specific DNA binding;
TRIM22	5	nucleus; defense response to virus; virus-host interaction; sequence-specific DNA binding transcription factor activity; cytoplasm;
FGF4	5	nucleus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; cytosol; negative regulation of apoptotic process;
CLOCK	5	nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; cytosol;
LHX2	5	nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; positive regulation of transcription, DNA-dependent;
ALDH3A1	5	aging; response to drug; response to cAMP; positive regulation of cell proliferation; cytosol;
HTR2A	5	aging; protein complex binding; response to drug; positive regulation of cell proliferation; cytosol;

Genes shared at least 2 KEGG pathways with RELA (count: 13)

Gene Symbol	Pathway Count	Pathway List
PIK3CG	7	Small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Apoptosis; Toll-like receptor signaling pathway; Prostate cancer; Pancreatic cancer;
PIK3R1	7	Small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Apoptosis; Toll-like receptor signaling pathway; Prostate cancer; Pancreatic cancer;
CCND1	5	Small cell lung cancer; Chronic myeloid leukemia; Acute myeloid leukemia; Prostate cancer; Pancreatic cancer;
MAPK1	5	Chronic myeloid leukemia; Acute myeloid leukemia; Toll-like receptor signaling pathway; Prostate cancer; Pancreatic cancer;
BAD	5	Chronic myeloid leukemia; Acute myeloid leukemia; Apoptosis; Prostate cancer; Pancreatic cancer;
MAPK3	5	Chronic myeloid leukemia; Acute myeloid leukemia; Toll-like receptor signaling pathway; Prostate cancer; Pancreatic cancer;
MAPK9	4	Epithelial cell signaling in Helicobacter pylori infection; Toll-like receptor signaling pathway; Pancreatic cancer; Adipocytokine signaling pathway;
CYCS	2	Small cell lung cancer; Apoptosis;
BIRC3	2	Small cell lung cancer; Apoptosis;
BIRC2	2	Small cell lung cancer; Apoptosis;
TGFBR1	2	Chronic myeloid leukemia; Pancreatic cancer;
FADD	2	Apoptosis; Toll-like receptor signaling pathway;
ERBB2	2	Prostate cancer; Pancreatic cancer;

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Region: chr11:65421067..65430565 View in gBrowse