ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TRIM22
Symbol Alias	STAF50, GPSTAF50, RNF94
Approved Name	tripartite motif containing 22
Previous Name	tripartite motif-containing 22
Location	11p15
Position	chr11:5710919-5758319, +
External Links	HGNC: 16379 Entrez Gene: 10346 Ensembl: ENSG00000132274 UCSC: uc001mbr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_29	chr11:5582423-7488751 (NCBI Build 36.1 (hg18))	1859865	11p15.4	Loss	De novo

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0070206	protein trimerization	Biological Process	IDA[17156811]	5
GO:0051607	defense response to virus	Biological Process		15
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0019048	virus-host interaction	Biological Process		54
GO:0016874	ligase activity	Molecular Function		12
GO:0016607	nuclear speck	Cellular Component		34
GO:0016567	protein ubiquitination	Biological Process		41
GO:0015030	Cajal body	Cellular Component		11
GO:0008270	zinc ion binding	Molecular Function		323
GO:0009615	response to virus	Biological Process	TAS[7797467]	21
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS[7797467]	158
GO:0006955	immune response	Biological Process	TAS[7797467]	45
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	TAS[7797467]	132
GO:0003714	transcription corepressor activity	Molecular Function	TAS[7797467]	29

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TRIM22 (count: 44)

Gene Symbol	Pathway Count	Pathway List
TRIM5	7	protein trimerization; defense response to virus; virus-host interaction; zinc ion binding; Golgi apparatus; nucleus; cytoplasm;
DPF2	6	intracellular membrane-bounded organelle; zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
HMGA1	6	virus-host interaction; response to virus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
IL16	6	virus-host interaction; regulation of transcription, DNA-dependent; immune response; transcription, DNA-dependent; nucleus; cytoplasm;
RFWD2	6	ligase activity; nuclear speck; protein ubiquitination; zinc ion binding; nucleus; cytoplasm;
RREB1	6	nuclear speck; zinc ion binding; regulation of transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
CBL	6	protein ubiquitination; zinc ion binding; regulation of transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
HINFP	6	Cajal body; zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
BCL11A	6	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm; transcription corepressor activity;
ZNF263	6	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
RELA	5	defense response to virus; virus-host interaction; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
ELK3	5	intracellular membrane-bounded organelle; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity; transcription corepressor activity;
MTA3	5	intracellular membrane-bounded organelle; zinc ion binding; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
SLU7	5	intracellular membrane-bounded organelle; nuclear speck; zinc ion binding; nucleus; cytoplasm;
DAXX	5	virus-host interaction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
MAPK1	5	virus-host interaction; Golgi apparatus; transcription, DNA-dependent; nucleus; cytoplasm;
NEDD4L	5	virus-host interaction; protein ubiquitination; transcription, DNA-dependent; nucleus; cytoplasm;
APBB1	5	nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
PSPC1	5	nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
RCHY1	5	nuclear speck; protein ubiquitination; zinc ion binding; nucleus; cytoplasm;
ZBTB16	5	nuclear speck; protein ubiquitination; zinc ion binding; transcription, DNA-dependent; nucleus;
NEUROD2	5	protein ubiquitination; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity; transcription corepressor activity;
NPAT	5	Cajal body; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity; transcription corepressor activity;
IGHMBP2	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
IKZF1	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
LMX1B	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
LPXN	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
PHF1	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
PRDM1	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
SF1	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; transcription corepressor activity;
ZFP37	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
ZNF169	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
ZNF215	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
ZNF367	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
ZNF396	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
ZNF397	5	zinc ion binding; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
ZNF70	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity;
ZNF77	5	zinc ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm;
GRHL1	5	regulation of transcription, DNA-dependent; Golgi apparatus; transcription, DNA-dependent; nucleus; cytoplasm;
HOXB1	5	regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
SCAI	5	regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm; transcription corepressor activity;
SCYL1	5	regulation of transcription, DNA-dependent; Golgi apparatus; transcription, DNA-dependent; nucleus; cytoplasm;
TFEB	5	regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity;
NCOR1	5	transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity; transcription corepressor activity;

Genes shared at least 2 KEGG pathways with TRIM22 (count: 0)

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Region: chr11:5710919..5758319 View in gBrowse