ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006955
Name immune response
Type biological process
No. of Genes in ADHDgene  51
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 51)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NFIL3 nuclear factor, interleukin 3 regulated 9q22 2(1/1/0) TAS[7565758]
IL16 interleukin 16 15q26.3 1(0/0/1) TAS[9144227]
IL1RN interleukin 1 receptor antagonist 2q14.2 2(1/1/0) NAS[7629520]
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 6p21.3 2(1/1/0) ISS; NAS

Genes from other sources Help (count: 47)

Approved Symbol Approved Name Source Evidence[PMID]
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Mapped by significant region TAS[8876214]
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) Mapped by significant region NAS[10932188]
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 Mapped by significant region IEA
CXCL12 chemokine (C-X-C motif) ligand 12 Mapped by PBA pathway IEA
IGLL1 immunoglobulin lambda-like polypeptide 1 Mapped by CNV NAS[2501791]
TAPBP TAP binding protein (tapasin) Mapped by LD-proxy TAS[9271576]
HLA-DOA major histocompatibility complex, class II, DO alpha Mapped by CNV IEA
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 Mapped by significant region IEA
FYB FYN binding protein Mapped by significant region TAS[9207119]
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) Mapped by CNV TAS[2142460]
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 Mapped by significant region TAS[7920628]
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 Mapped by CNV TAS[2247090]
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 Mapped by CNV NAS[2461352]
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) Mapped by significant region IEA
SUSD2 sushi domain containing 2 Mapped by CNV IEA
IGSF6 immunoglobulin superfamily, member 6 Mapped by significant region TAS[9809579]
CTSG cathepsin G Mapped by significant region TAS[2569462]
TRIM22 tripartite motif containing 22 Mapped by CNV TAS[7797467]
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Mapped by CNV TAS[2138330]
CCL19 chemokine (C-C motif) ligand 19 Mapped by LD-proxy IEA
SPN sialophorin Mapped by CNV TAS[2023632]
PTGDR2 prostaglandin D2 receptor 2 Mapped by significant region TAS[9973380]
IRF8 interferon regulatory factor 8 Mapped by significant region TAS[8861914]
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) Mapped by CNV TAS[2139735]
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) Mapped by CNV NAS[2531080]
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 Mapped by significant region TAS[7515885]
CIITA class II, major histocompatibility complex, transactivator Mapped by significant region TAS[8402893]
CCL28 chemokine (C-C motif) ligand 28 Mapped by significant region IEA
LTB4R leukotriene B4 receptor Mapped by significant region TAS[9177352]
CTSC cathepsin C Mapped by significant region TAS[9092576]
IL18 interleukin 18 (interferon-gamma-inducing factor) Mapped by significant region TAS[8999896]
MR1 major histocompatibility complex, class I-related Mapped by significant region IEA
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway TAS[8639485]
IL7R interleukin 7 receptor Mapped by significant region TAS[9843216]
TLR4 toll-like receptor 4 Mapped by significant region TAS[10426995]
IL32 interleukin 32 Mapped by significant region TAS[1729377]
PRG3 proteoglycan 3 Mapped by significant region IEA
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region TAS[2187191]
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region TAS[9751059]
CTSW cathepsin W Mapped by significant region TAS[9823953]
PTGER4 prostaglandin E receptor 4 (subtype EP4) Mapped by significant region IEP[8862514]
IGHV1OR15-1 immunoglobulin heavy variable 1/OR15-1 (non-functional) Mapped by significant region NAS[2841108]
FTH1 ferritin, heavy polypeptide 1 Mapped by significant region ISS
CCL27 chemokine (C-C motif) ligand 27 Mapped by LD-proxy IEA
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle Mapped by CNV IEA
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 Mapped by significant region IEA
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 Mapped by significant region IEA