ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LTB4R
Previous Symbol	P2RY7, GPR16, CMKRL1
Symbol Alias	BLTR, P2Y7, LTB4R1
Approved Name	leukotriene B4 receptor
Location	14q11.2-q12
Position	chr14:24780705-24787242, +
External Links	HGNC: 6713 Entrez Gene: 1241 Ensembl: ENSG00000213903 UCSC: uc001wos.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006955	immune response	Biological Process	TAS[9177352]	45
GO:0006954	inflammatory response	Biological Process		51
GO:0006936	muscle contraction	Biological Process	TAS[8702478]	18
GO:0006928	cellular component movement	Biological Process	TAS[9177352]	16
GO:0005887	integral to plasma membrane	Cellular Component	TAS[9177352]	220
GO:0005886	plasma membrane	Cellular Component		772
GO:0004974	leukotriene receptor activity	Molecular Function	TAS[9177352]	2
GO:0001632	leukotriene B4 receptor activity	Molecular Function		1
GO:0000166	nucleotide binding	Molecular Function	TAS[8702478]	73
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	TAS[9177352]	72
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological Process	TAS[8702478]	12

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04080	Neuroactive ligand-receptor interaction	93

Genes shared at least 5 GO terms with LTB4R (count: 1)

Gene Symbol	Pathway Count	Pathway List
CCR5	5	immune response; inflammatory response; integral to plasma membrane; plasma membrane; G-protein coupled receptor signaling pathway;

Genes shared at least 2 KEGG pathways with LTB4R (count: 0)

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Region: chr14:24780705..24787242 View in gBrowse