ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007200
Name phospholipase C-activating G-protein coupled receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  13
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 13)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) ISS
ADRA1A adrenoceptor alpha 1A 8p21.2 3(2/1/0) IEA

Genes from other sources Help (count: 11)

Approved Symbol Approved Name Source Evidence[PMID]
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region IDA[10438939]
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 Mapped by significant region TAS[8670200]
CCKAR cholecystokinin A receptor Mapped by CNV TAS[8343165]
GNG13 guanine nucleotide binding protein (G protein), gamma 13 Mapped by significant region IEA
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway IDA[11022047]
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 Mapped by significant region TAS[8159738]
NTSR2 neurotensin receptor 2 Mapped by significant region IEA
NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) Mapped by significant region IEA
GPR139 G protein-coupled receptor 139 Mapped by significant region IEA
LTB4R leukotriene B4 receptor Mapped by significant region TAS[8702478]
CCKBR cholecystokinin B receptor Mapped by CNV; Mapped by PBA pathway TAS[8455720]