ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol IL1RN
Symbol Alias IL1RA, ICIL-1RA, IL1F3, IRAP, IL-1RN, MGC10430
Approved Name interleukin 1 receptor antagonist
Name Alias "interleukin-1 receptor antagonist protein", "intracellular interleukin-1 receptor antagonist"
Location 2q14.2
Position chr2:113864791-113891593, 1
External Links HGNC: 6000
Entrez Gene: 3557
Ensembl: ENSG00000136689
UCSC: uc002tjb.3
No. of Studies 2 (significant: 1; non-significant: 1; trend: 0)
Source Literature-origin

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Misener VL, 2004 (b) TDT results for the intron 2 86bp VNTR polymorphism did not support a role for the IL1RN gene in ADHD Non-significant
Segman RH, 2002 Results support a small but significant contribution of the IL-1Ra VNTR to susceptibility to ADHD. Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 1)

Gene related regions (count: 0)

Gene related GO terms (count: 29)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 29)


Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with IL1RN (count: 8)

Genes shared at least 2 KEGG pathways with IL1RN (count: 0)

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Region: chr2:113864791..113891593 View in gBrowse
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