ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005813
Name centrosome
Type cellular component
No. of Genes in ADHDgene  78
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 78)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 7p22 1(0/1/0) NAS[9546394]
POC5 POC5 centriolar protein 5q13.3 1(0/1/0) IDA
IL1RN interleukin 1 receptor antagonist 2q14.2 2(1/1/0) IDA
DISC1 disrupted in schizophrenia 1 1q42.1 1(1/0/0) IDA[18955030]
CEP112 centrosomal protein 112kDa 17q24.2 1(0/0/1) IDA
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) IDA

Genes from other sources Help (count: 72)

Approved Symbol Approved Name Source Evidence[PMID]
TUBGCP4 tubulin, gamma complex associated protein 4 Mapped by LD-proxy IDA
TUBGCP5 tubulin, gamma complex associated protein 5 Mapped by significant region; Mapped by PBA pathway IDA
CEP72 centrosomal protein 72kDa Mapped by significant region IDA
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 Mapped by significant region IDA[17498979]
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region IDA[12529434]
FLII flightless I homolog (Drosophila) Mapped by significant region IDA
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV IDA
ANKRD32 ankyrin repeat domain 32 Mapped by LD-proxy IEA
FBXL7 F-box and leucine-rich repeat protein 7 Mapped by significant region ISS
DCTN3 dynactin 3 (p22) Mapped by LD-proxy IDA
TUBGCP6 tubulin, gamma complex associated protein 6 Mapped by PBA pathway IDA
MZT2B mitotic spindle organizing protein 2B Mapped by significant region IDA
CENPJ centromere protein J Mapped by PBA pathway IDA
DPF2 D4, zinc and double PHD fingers family 2 Mapped by significant region IDA
CDC45 cell division cycle 45 Mapped by CNV IDA
CLASP1 cytoplasmic linker associated protein 1 Mapped by PBA pathway IDA
FOPNL FGFR1OP N-terminal like Mapped by CNV; Mapped by significant region IDA
PLK1 polo-like kinase 1 Mapped by significant region IDA
DCTN5 dynactin 5 (p25) Mapped by significant region IDA
KIF23 kinesin family member 23 Mapped by PBA pathway IDA
KIAA1731 KIAA1731 Mapped by significant region IDA
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) Mapped by significant region IEA
CEP164 centrosomal protein 164kDa Mapped by significant region IDA
PPP4C protein phosphatase 4, catalytic subunit Mapped by CNV NAS
HYLS1 hydrolethalus syndrome 1 Mapped by significant region IDA
RABGAP1 RAB GTPase activating protein 1 Mapped by significant region TAS[10202141]
CHEK1 checkpoint kinase 1 Mapped by significant region IDA[15311285]
MARK4 MAP/microtubule affinity-regulating kinase 4 Mapped by PBA pathway IDA[14594945]
MIB1 mindbomb E3 ubiquitin protein ligase 1 Mapped by significant region IDA
CDC25B cell division cycle 25B Mapped by CNV IDA[15908796]
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway IDA
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) Mapped by CNV IDA
CNTRL centriolin Mapped by significant region IDA[15337773]
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase Mapped by PBA pathway TAS[11237715]
USP2 ubiquitin specific peptidase 2 Mapped by significant region IEA
B9D1 B9 protein domain 1 Mapped by significant region IDA[19208769]
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IDA[11283619]
C2CD3 C2 calcium-dependent domain containing 3 Mapped by significant region IDA
MZT2A mitotic spindle organizing protein 2A Mapped by CNV; Mapped by significant region IDA; ISS
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) Mapped by significant region IDA
CKAP5 cytoskeleton associated protein 5 Mapped by PBA pathway IDA[14718566]
NDE1 nudE neurodevelopment protein 1 Mapped by CNV; Mapped by significant region IDA
TUBGCP2 tubulin, gamma complex associated protein 2 Mapped by Literature SNP; Mapped by CNV; Mapped by PBA pathway IDA
UXT ubiquitously-expressed, prefoldin-like chaperone Mapped by PBA pathway IDA[16221885]
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 Mapped by CNV IDA
KATNB1 katanin p80 (WD repeat containing) subunit B 1 Mapped by PBA pathway IEA
CCDC85B coiled-coil domain containing 85B Mapped by significant region IDA[17014843]
HOOK3 hook microtubule-tethering protein 3 Mapped by PBA pathway IDA; ISS
RAB11FIP3 RAB11 family interacting protein 3 (class II) Mapped by significant region IDA
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway IDA; ISS
ARL2 ADP-ribosylation factor-like 2 Mapped by significant region IDA[16525022]
CEP76 centrosomal protein 76kDa Mapped by CNV IDA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IDA
C10orf90 chromosome 10 open reading frame 90 Mapped by CNV IDA
SAC3D1 SAC3 domain containing 1 Mapped by significant region IEA
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region IDA
CEP57 centrosomal protein 57kDa Mapped by significant region IDA
RANBP1 RAN binding protein 1 Mapped by CNV IEA
CCP110 centriolar coiled coil protein 110kDa Mapped by significant region IDA
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) Mapped by significant region IDA
MAPRE1 microtubule-associated protein, RP/EB family, member 1 Mapped by PBA pathway IDA
CEP250 centrosomal protein 250kDa Mapped by PBA pathway IDA
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) Mapped by significant region IDA
TUBG1 tubulin, gamma 1 Mapped by PBA pathway IDA
CEP85L centrosomal protein 85kDa-like Mapped by significant region TAS
AHI1 Abelson helper integration site 1 Mapped by significant region IDA[18633336]
RAB6C RAB6C, member RAS oncogene family Mapped by significant region IDA
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 Mapped by significant region IDA[17015463]
NDN necdin, melanoma antigen (MAGE) family member Mapped by CNV; Mapped by significant region IEA
CCDC15 coiled-coil domain containing 15 Mapped by significant region IDA
AATF apoptosis antagonizing transcription factor Mapped by CNV IDA
KIAA0368 KIAA0368 Mapped by significant region IDA[15496406]