ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NDN
Symbol Alias	HsT16328, PWCR
Approved Name	necdin homolog (mouse)
Previous Name	necdin (mouse) homolog
Location	15q11-q12
Position	chr15:23930554-23932450, -
External Links	HGNC: 7675 Entrez Gene: 4692 Ensembl: ENSG00000182636 UCSC: uc001ywk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_46	chr15:21016722-25902239 (NCBI Build 36.1 (hg18))	4933636	15q11.2-15q13.1	Gain

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
15q11.2-13.3	chr15:20700000-33600000	1 (1/0/0)

Gene related GO terms (count: 22)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001764	neuron migration	Biological Process		21
GO:0003677	DNA binding	Molecular Function		220
GO:0003016	respiratory system process	Biological Process		2
GO:0005634	nucleus	Cellular Component		770
GO:0005813	centrosome	Cellular Component		71
GO:0005829	cytosol	Cellular Component		447
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0007399	nervous system development	Biological Process	TAS[9630521]	54
GO:0007413	axonal fasciculation	Biological Process		3
GO:0007417	central nervous system development	Biological Process		22
GO:0048011	nerve growth factor receptor signaling pathway	Biological Process		42
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS[9630521]	59
GO:0048871	multicellular organismal homeostasis	Biological Process		1
GO:0008347	glial cell migration	Biological Process		1
GO:0071514	genetic imprinting	Biological Process		1
GO:0009791	post-embryonic development	Biological Process		16
GO:0019233	sensory perception of pain	Biological Process		17
GO:0040008	regulation of growth	Biological Process		5
GO:0042995	cell projection	Cellular Component		12
GO:0043015	gamma-tubulin binding	Molecular Function		5
GO:0043204	perikaryon	Cellular Component		12

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NDN (count: 5)

Gene Symbol	Pathway Count	Pathway List
MAPK1	7	DNA binding; nucleus; cytosol; transcription, DNA-dependent; nerve growth factor receptor signaling pathway; sensory perception of pain; perikaryon;
HMGA1	6	DNA binding; nucleus; cytosol; transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of cell proliferation;
EEF1D	5	DNA binding; nucleus; cytosol; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
MAP1S	5	DNA binding; nucleus; cytosol; nervous system development; cell projection;
ZBTB16	5	DNA binding; nucleus; transcription, DNA-dependent; central nervous system development; negative regulation of cell proliferation;

Genes shared at least 2 KEGG pathways with NDN (count: 0)

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Region: chr15:23930554..23932450 View in gBrowse