ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TRNT1
Symbol Alias	MtCCA, CGI-47, CCA1
Approved Name	tRNA nucleotidyl transferase, CCA-adding, 1
Location	3p25.1
Position	chr3:3168600-3192563, +
External Links	HGNC: 17341 Entrez Gene: 51095 Ensembl: ENSG00000072756 UCSC: uc003bpp.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_15	chr3:2969491-4461303 (NCBI Build 36.1 (hg18))	1538470	3p26.3-3p26.2	Loss

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0052927	CTP:tRNA cytidylyltransferase activity	Molecular Function		1
GO:0052928	CTP:3'-cytidine-tRNA cytidylyltransferase activity	Molecular Function		1
GO:0052929	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	Molecular Function		1
GO:0001680	tRNA 3'-terminal CCA addition	Biological Process		1
GO:0000049	tRNA binding	Molecular Function	IDA[11504732]	7
GO:0006626	protein targeting to mitochondrion	Biological Process	TAS[11504732]	7
GO:0005813	centrosome	Cellular Component		71
GO:0042780	tRNA 3'-end processing	Biological Process	IDA[11504732]	1
GO:0009022	tRNA nucleotidyltransferase activity	Molecular Function		1
GO:0005524	ATP binding	Molecular Function	TAS[11504732]	228
GO:0004810	tRNA adenylyltransferase activity	Molecular Function	IDA[11504732]	1
GO:0005739	mitochondrion	Cellular Component		183
GO:0005622	intracellular	Cellular Component		67

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03013	RNA transport	15	RNA transport from the nucleus to the cytoplasm is fundamen...... RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation. More...

Genes shared at least 5 GO terms with TRNT1 (count: 0)

Genes shared at least 2 KEGG pathways with TRNT1 (count: 0)

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Region: chr3:3168600..3192563 View in gBrowse