ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TUBG1
Previous Symbol	TUBG
Symbol Alias	TUBGCP1
Approved Name	tubulin, gamma 1
Previous Name	tubulin, gamma polypeptide
Location	17q21.31
Position	chr17:40761358-40767256, +
External Links	HGNC: 12417 Entrez Gene: 7283 Ensembl: ENSG00000131462 UCSC: uc002ian.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process	TAS[1904010]	39

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000930	gamma-tubulin complex	Cellular Component	TAS[9566969]	3
GO:0000794	condensed nuclear chromosome	Cellular Component		6
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0005525	GTP binding	Molecular Function		53
GO:0005515	protein binding	Molecular Function		910
GO:0005200	structural constituent of cytoskeleton	Molecular Function	TAS[1904010]	14
GO:0003924	GTPase activity	Molecular Function		41
GO:0005829	cytosol	Cellular Component		447
GO:0005827	polar microtubule	Cellular Component	IDA[9566969]	1
GO:0005813	centrosome	Cellular Component		71
GO:0005737	cytoplasm	Cellular Component	IDA[9566969]	690
GO:0051258	protein polymerization	Biological Process		7
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process		29
GO:0000212	meiotic spindle organization	Biological Process		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TUBG1 (count: 29)

Gene Symbol	Pathway Count	Pathway List
CKAP5	7	gamma-tubulin complex; mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
CDK5RAP2	7	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
MAPRE1	7	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
PAFAH1B1	7	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
CENPJ	6	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
CEP164	6	mitotic cell cycle; protein binding; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
CEP57	6	mitotic cell cycle; protein binding; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
CLASP1	6	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
TUBA4A	6	mitotic cell cycle; GTP binding; GTPase activity; cytosol; protein polymerization; G2/M transition of mitotic cell cycle;
TUBGCP2	6	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
RAN	6	microtubule cytoskeleton organization; GTP binding; protein binding; GTPase activity; cytosol; cytoplasm;
UXT	5	gamma-tubulin complex; microtubule cytoskeleton organization; protein binding; centrosome; cytoplasm;
CHEK1	5	condensed nuclear chromosome; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
SMC1A	5	condensed nuclear chromosome; mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytoplasm;
CEP250	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
CEP76	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
CLASP2	5	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; cytoplasm;
CNTRL	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
DCTN3	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
KIF23	5	mitotic cell cycle; microtubule cytoskeleton organization; protein binding; cytosol; centrosome;
NDE1	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
NUMA1	5	mitotic cell cycle; protein binding; cytosol; cytoplasm; G2/M transition of mitotic cell cycle;
PLK1	5	mitotic cell cycle; protein binding; cytosol; centrosome; G2/M transition of mitotic cell cycle;
PRKAR2B	5	mitotic cell cycle; cytosol; centrosome; cytoplasm; G2/M transition of mitotic cell cycle;
TUBGCP4	5	mitotic cell cycle; structural constituent of cytoskeleton; cytosol; centrosome; G2/M transition of mitotic cell cycle;
TUBGCP5	5	mitotic cell cycle; microtubule cytoskeleton organization; cytosol; centrosome; G2/M transition of mitotic cell cycle;
TUBGCP6	5	mitotic cell cycle; microtubule cytoskeleton organization; cytosol; centrosome; G2/M transition of mitotic cell cycle;
APC	5	microtubule cytoskeleton organization; protein binding; cytosol; centrosome; cytoplasm;
TUBA3D	5	GTP binding; protein binding; GTPase activity; cytoplasm; protein polymerization;

Genes shared at least 2 KEGG pathways with TUBG1 (count: 0)

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Region: chr17:40761358..40767256 View in gBrowse